PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gh_D10G0038
Organism
Gossypium hirsutum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family HD-ZIP
Protein Properties Length: 853aa    MW: 93770.9 Da    PI: 6.0305
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gh_D10G0038genomeNAU-NBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox58.61e-181977357
                 --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
     Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
                 k  ++t+eq+e+Le++++++++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  Gh_D10G0038 19 KYVRYTPEQVEALERVYNECPKPSSLRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 77
                 6789*****************************************************97 PP
2START170.61e-531693762204
                  HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EEEEEEEEX CS
        START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..galqlmvae 97 
                  +aee+++e+++ka+ ++  Wv++  +++g++++ +++ s+++sg a+ra+g+v  +++  v+e+l+d++ W ++++ +++l  i ++  g+++l++++
  Gh_D10G0038 169 IAEETLAEFLSKATGTAVDWVQMIGMKPGPDSIGIVAVSRNCSGVAARACGLVSLEPT-KVAEILKDRPSWYRDCRCIDVLSIIPTAngGTIELIYMQ 265
                  7899******************************************************.8888888888****************9999********* PP

                  XTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHHHHHHHHHH CS
        START  98 lqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrslvksglae 191
                  ++a+++l++ Rdf+++Ry+ +l++g +vi+++S++s +  p+   + s+vRae+lpSg+li+p+++g+s +++v+hvdl+ ++++++lr+l++s+ + 
  Gh_D10G0038 266 TYAPTTLAAaRDFWTLRYTTSLEDGNLVICERSLTSSTGGPTgppTTSFVRAEMLPSGFLIRPCDGGGSIIHIVDHVDLDVWSVPEVLRPLYESSKIL 363
                  *************************************99999999***************************************************** PP

                  HHHHHHHHTXXXX CS
        START 192 gaktwvatlqrqc 204
                  ++k++ a+l++ +
  Gh_D10G0038 364 AQKMTIAALRHIR 376
                  ********99865 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.601.2E-18477IPR009057Homeodomain-like
PROSITE profilePS5007115.7581478IPR001356Homeobox domain
SMARTSM003891.6E-151682IPR001356Homeobox domain
PfamPF000462.7E-161977IPR001356Homeobox domain
CDDcd000868.29E-171979No hitNo description
SuperFamilySSF466891.75E-161981IPR009057Homeodomain-like
CDDcd146861.81E-671110No hitNo description
PROSITE profilePS5084826.539159387IPR002913START domain
CDDcd088752.43E-66163379No hitNo description
SMARTSM002345.4E-50168378IPR002913START domain
Gene3DG3DSA:3.30.530.209.1E-23168373IPR023393START-like domain
PfamPF018523.0E-51169376IPR002913START domain
SuperFamilySSF559611.51E-37169380No hitNo description
SuperFamilySSF559618.52E-6416501No hitNo description
SuperFamilySSF559618.52E-6529602No hitNo description
PfamPF086703.0E-48705852IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009855Biological Processdetermination of bilateral symmetry
GO:0009944Biological Processpolarity specification of adaxial/abaxial axis
GO:0010072Biological Processprimary shoot apical meristem specification
GO:0080060Biological Processintegument development
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 853 aa     Download sequence    Send to blast
MALSMHKESL NNKQMDSSKY VRYTPEQVEA LERVYNECPK PSSLRRQQLI RECPILSNIE  60
PKQIKVWFQN RRCREKQRKE ASRLQTVNRK LTAMNKLLME ENDRLQKQVS HLVYENGYMK  120
QQLQTASVTT TDNNSCESVV VSGQHQQQQN PTPRHPQRDA NNPAGLLTIA EETLAEFLSK  180
ATGTAVDWVQ MIGMKPGPDS IGIVAVSRNC SGVAARACGL VSLEPTKVAE ILKDRPSWYR  240
DCRCIDVLSI IPTANGGTIE LIYMQTYAPT TLAAARDFWT LRYTTSLEDG NLVICERSLT  300
SSTGGPTGPP TTSFVRAEML PSGFLIRPCD GGGSIIHIVD HVDLDVWSVP EVLRPLYESS  360
KILAQKMTIA ALRHIRQIAQ ETNGEIQYGG GRQPAVLRTF SQRLCRGFND AVNGFVDDGW  420
SLMGSDGVED VTIMINSSPG KFFGSQYNTS MVPSFGGGVL CAKASMLLQS VPPALLVRFL  480
REHRSEWADY GIDTYSAACL KPNPYTVPCA RPSGFPSSQV ILPLAHTVEH EEFLEVVRLE  540
GQAFTPEDVA LARDMYLLQL CSGIDENAVG ACAQLVFAPI DESFADNAPL LPSGFRVIPL  600
DSKPVMDGPG AARTLDLAST LEVGPGSNRS TGDGEPNSYN LRSVLTIAFQ FTFENHLRDD  660
VASMARQYVR SVVGSVQRVA MAIAPSRISP GLGPKSLPGS PEALTLARWI CRSYRIHTGG  720
ELLRADSQSG DTLLEQLWNH SDAIMCCSLK TNASPVFTFA NQAGLDMLET TLVALQDIML  780
DKILDEAGRK SLCTEFSKIM QQGFAHLPAG ICVSSMGRPL SYEQAIVWKV VDDDNDDAAN  840
HCLGLMFVNW SFV
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Ghi.117470.0boll| ovule| root
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed at the youngest stages of ovule development, predominantly to the adaxial side of the ovule primordium. Later, expression becomes restricted to a region in the distal chalaza. When the integuments initiate, expressed in the inner integument, with highest expression in the inner layer of the inner integument. Expressed in the vegetative shoot apical meristem (SAM) and initially throughout the presumptive cotyledons. At the globular stage, just before cotyledon outgrowth, expressed at high levels in cotyledon adaxial domains. Expression is lost from the SAM of torpedo stage embryos but is regained late in embryogenesis, extending to young primordia after germination, and becoming progressively restricted to the adaxial domain and the vasculature. Preferentially expressed in the adaxial domain of the developing leaf. Expressed throughout the plastochron 0 (P0) leaf primordium and expression increases in P1 to become preferentially localized to the adaxial leaf domain by the P2 stage (polar expression). {ECO:0000269|PubMed:11395776, ECO:0000269|PubMed:15328016}.
UniprotTISSUE SPECIFICITY: Expressed in the center of the meristem and on the adaxial side of the leaves. {ECO:0000269|PubMed:11395776}.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the determination of adaxial-abaxial polarity in ovule primordium. Specifies adaxial leaf fates. {ECO:0000269|PubMed:11395776, ECO:0000269|PubMed:15328016, ECO:0000269|PubMed:15598805}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR165 and miR166. {ECO:0000269|PubMed:14999284, ECO:0000269|PubMed:16033795, ECO:0000269|PubMed:17237362}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016717554.10.0PREDICTED: homeobox-leucine zipper protein ATHB-14-like isoform X1
RefseqXP_016717555.10.0PREDICTED: homeobox-leucine zipper protein ATHB-14-like isoform X2
SwissprotO042910.0ATB14_ARATH; Homeobox-leucine zipper protein ATHB-14
TrEMBLA0A1U8LWC60.0A0A1U8LWC6_GOSHI; homeobox-leucine zipper protein ATHB-14-like isoform X1
STRINGGorai.011G004200.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM42562653
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G34710.10.0HD-ZIP family protein
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  3. Müller CJ, et al.
    PHABULOSA Mediates an Auxin Signaling Loop to Regulate Vascular Patterning in Arabidopsis.
    Plant Physiol., 2016. 170(2): p. 956-70
    [PMID:26637548]
  4. Yamada T,Sasaki Y,Hashimoto K,Nakajima K,Gasser CS
    CORONA, PHABULOSA and PHAVOLUTA collaborate with BELL1 to confine WUSCHEL expression to the nucellus in Arabidopsis ovules.
    Development, 2016. 143(3): p. 422-6
    [PMID:26700684]
  5. Kim ES, et al.
    HAWAIIAN SKIRT regulates the quiescent center-independent meristem activity in Arabidopsis roots.
    Physiol Plant, 2016. 157(2): p. 221-33
    [PMID:26968317]
  6. Husbands AY,Aggarwal V,Ha T,Timmermans MC
    In Planta Single-Molecule Pull-Down Reveals Tetrameric Stoichiometry of HD-ZIPIII:LITTLE ZIPPER Complexes.
    Plant Cell, 2016. 28(8): p. 1783-94
    [PMID:27385814]
  7. Di Ruocco G, et al.
    Differential spatial distribution of miR165/6 determines variability in plant root anatomy.
    Development, 2018.
    [PMID:29158439]
  8. Wójcik AM,Nodine MD,Gaj MD
    miR160 and miR166/165 Contribute to the LEC2-Mediated Auxin Response Involved in the Somatic Embryogenesis Induction in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 2024
    [PMID:29321785]
  9. Hashimoto K,Miyashima S,Sato-Nara K,Yamada T,Nakajima K
    Functionally Diversified Members of the MIR165/6 Gene Family Regulate Ovule Morphogenesis in Arabidopsis thaliana.
    Plant Cell Physiol., 2018. 59(5): p. 1017-1026
    [PMID:29462472]