PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

ERF

Protein Properties

Length: 257aa MW: 28649.2 Da PI: 7.5474

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_A13G1833	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	57.8	2.8e-18	19	68	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 ++ GVr+++ +g+WvAeI+d + ++ r +lg+f taeeAa+a+++a+ l+g Gh_A13G1833 19 KFVGVRQRP-SGKWVAEIKDTT---QKIRMWLGTFETAEEAARAYDEAACLLRG 68 799****.7*****32...35********************99987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF54171	1.37E-19	19	77	IPR016177	DNA-binding domain
CDD	cd00018	8.68E-33	19	78	No hit	No description
Pfam	PF00847	8.8E-13	19	68	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.6E-28	19	77	IPR001471	AP2/ERF domain
SMART	SM00380	2.8E-37	19	82	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	19.823	19	76	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.2E-8	20	31	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.2E-8	42	58	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 257 aa Download sequence Send to blast
MEHQVQTQQK GKFKERRNKF VGVRQRPSGK WVAEIKDTTQ KIRMWLGTFE TAEEAARAYD 60 EAACLLRGSN TRTNFATHVP TDSHLSLKIR NLLNHKKSLR QGKNNNSNST TNSNKITIKA 120 STIVGSNDSI NSSISNAGTH SFMCNSLVFD GAYRPELSGF VGELGPDPSQ LGQSWMIPTG 180 FDQIPLSQGL ELPQEVGVLP QGIDQELMEF ERLKVERQVS ATLYAMNGVN EYLQSAAFDP 240 NDAIWDLPTL CHLFCQS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	6e-15	20	79	3	63	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the symbiotic nodule signaling pathway in response to rhizobial stimulation. Functions as a transcriptional regulator required for root infection by symbiotic rhizobia, infection thread (IT) formation, and nodule development. May coordinate these processes (PubMed:28503742, PubMed:28028038, PubMed:28068194). Functions downstream of the CCAMK-CYCLOPS complex (PubMed:28503742, PubMed:28028038). Probably not involved in arbuscular mycorrhizal (AM) symbiosis (PubMed:28068194). {ECO:0000269\|PubMed:28028038, ECO:0000269\|PubMed:28068194, ECO:0000269\|PubMed:28503742}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced in nodules 7 days after rhizobial inoculation. {ECO:0000269\|PubMed:28028038, ECO:0000269\|PubMed:28503742}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AM466283	4e-42	AM466283.1 Vitis vinifera, whole genome shotgun sequence, contig VV78X245563.19, clone ENTAV 115.
GenBank	FQ396586	4e-42	FQ396586.1 Vitis vinifera clone SS0AEB9YH10.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016733556.1	0.0	PREDICTED: ethylene-responsive transcription factor RAP2-11-like
Swissprot	A0A1X9PY88	9e-81	ERN1_LOTJA; Ethylene-responsive transcription factor ERN1
TrEMBL	A0A1U8N391	0.0	A0A1U8N391_GOSHI; ethylene-responsive transcription factor RAP2-11-like
STRING	Gorai.013G244500.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM7526	26	41

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G19790.1	2e-56	related to AP2 11

Publications ? help Back to Top
Yano K, et al. Function and evolution of a Lotus japonicus AP2/ERF family transcription factor that is required for development of infection threads. DNA Res., 2017. 24(2): p. 193-203 [PMID:28028038] Kawaharada Y,James EK,Kelly S,Sandal N,Stougaard J The Ethylene Responsive Factor Required for Nodulation 1 (ERN1) Transcription Factor Is Required for Infection-Thread Formation in Lotus japonicus. Mol. Plant Microbe Interact., 2017. 30(3): p. 194-204 [PMID:28068194] Cerri MR, et al. The ERN1 transcription factor gene is a target of the CCaMK/CYCLOPS complex and controls rhizobial infection in Lotus japonicus. New Phytol., 2017. 215(1): p. 323-337 [PMID:28503742]