PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

ERF

Protein Properties

Length: 181aa MW: 20976.2 Da PI: 6.8056

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_A12G2541	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	52.7	1e-16	80	129	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 +y+GVr+++ +g+ +AeIrdp+ r +r++lg+f+tae Aa+a+++a+ +++g Gh_A12G2541 80 RYRGVRQRP-WGKRAAEIRDPK----RaARVWLGTFDTAEAAARAYDRAAIRFRG 129 8******.8998**83....57**********************997 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	1.54E-17	79	139	No hit	No description
SuperFamily	SSF54171	7.85E-21	80	139	IPR016177	DNA-binding domain
Pfam	PF00847	5.9E-11	80	129	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	2.4E-30	80	138	IPR001471	AP2/ERF domain
SMART	SM00380	9.9E-36	80	143	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	23.92	80	137	IPR001471	AP2/ERF domain
PRINTS	PR00367	6.5E-11	81	92	IPR001471	AP2/ERF domain
PRINTS	PR00367	6.5E-11	103	119	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 181 aa Download sequence Send to blast
MWVQFDSENT HYVMDNYNRN QSRALTLTRE QEYDIMVSTL LHVINGGQSA TSNNGFCFNS 60 HFPPIQPARV PLPTTTNRKR YRGVRQRPWG KRAAEIRDPK RAARVWLGTF DTAEAAARAY 120 DRAAIRFRGD KAKINFPLSD YEMRGEEEKQ SGEEGESSND NENGWKIFSE EEFRELMMVD 180 S

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2gcc_A	4e-24	79	138	4	64	ATERF1
3gcc_A	4e-24	79	138	4	64	ATERF1
Search in ModeBase

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	109867054	3e-73

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed during the S phase of the cell cycle. {ECO:0000269\|PubMed:23616605}.
Uniprot	TISSUE SPECIFICITY: Strongly expressed in proliferating cells. Detected in root tips, stipules, shoot apex, floral tissues, young siliques and abscission zones. {ECO:0000269\|PubMed:23616605}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator of cell proliferation and axillary bud outgrowth. Involved in maintaining the structure of the shoot apical meristem as well as plastochron and phyllotaxy. Activates several genes involved in cell cycle regulation and dormancy breaking, including CYCD3-3, DPA, and BARD1. Strongly down-regulates DRM1, DRMH1, MARD1 and several genes encoding different types of cell wall-remodeling proteins. {ECO:0000269\|PubMed:23616605}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Transiently up-regulated 6 to 15 hours after decapitation. {ECO:0000269\|PubMed:23616605}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016711433.1	1e-133	PREDICTED: ethylene-responsive transcription factor ERF114-like
Swissprot	Q9FH54	1e-32	EF114_ARATH; Ethylene-responsive transcription factor ERF114
TrEMBL	A0A1U8LDJ1	1e-132	A0A1U8LDJ1_GOSHI; ethylene-responsive transcription factor ERF114-like
STRING	Gorai.008G075600.1	1e-111	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM18345	4	9

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G61890.1	5e-25	ERF family protein

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kong X, et al. PHB3 Maintains Root Stem Cell Niche Identity through ROS-Responsive AP2/ERF Transcription Factors in Arabidopsis. Cell Rep, 2018. 22(5): p. 1350-1363 [PMID:29386120]