PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gh_A12G1884
Organism
Gossypium hirsutum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family HSF
Protein Properties Length: 511aa    MW: 56227.5 Da    PI: 4.7963
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gh_A12G1884genomeNAU-NBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind114.95e-36451362102
                   HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS
  HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 
                   Fl+k+y++++d++++ ++sws ++nsfvv+++ efa+++LpkyFkh+nf+SFvRQLn+YgF+kv+ ++         weF+++ F +g+k+ll++i 
   Gh_A12G1884  45 FLSKTYDMVDDPATDAIVSWSPTNNSFVVWNPPEFARDLLPKYFKHNNFSSFVRQLNTYGFRKVDPDR---------WEFANEGFLRGQKHLLRNIS 132
                   9********************999*****************************************999.........******************** PP

                   XXXX CS
  HSF_DNA-bind  99 rkks 102
                   r+k 
   Gh_A12G1884 133 RRKP 136
                   *986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF467851.31E-3640134IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004159.7E-6641134IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene3DG3DSA:1.10.10.102.6E-4041134IPR011991Winged helix-turn-helix DNA-binding domain
PRINTSPR000561.1E-204568IPR000232Heat shock factor (HSF)-type, DNA-binding
PfamPF004471.6E-3245134IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.1E-208395IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS00434084108IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.1E-2096108IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 511 aa     Download sequence    Send to blast
MDGVSSSSNN QTDASTSGGG TQTATQPQPM PQPVAGHSAN GPPPFLSKTY DMVDDPATDA  60
IVSWSPTNNS FVVWNPPEFA RDLLPKYFKH NNFSSFVRQL NTYGFRKVDP DRWEFANEGF  120
LRGQKHLLRN ISRRKPAHGH GHQQTQQPHG QSSSMGACVE VGKFGLEEEV ERLKRDKNVL  180
MQELVRLRQQ QQTTDNQLQN MVQRLQGMEQ RQQQMMSFLA KAVQSPSFFA QFVHQQNESN  240
RRISETNKKR RLKQDGIIDK DHSTASDGQI VKYQPLMNDA KAMLMQMMKG DASPRLDSFN  300
NSNEHTLIGD GSSSSSGLDG GNSSSRVSGV TLQEVSPTSG ISGHCPSAAI SEIQSSPCTT  360
SSERITTAEL PDVSALIGAE KPPSVSVTQT DVIMPDLSQI LEMVPESIVD IPTEMGNDGL  420
IDPDTLAVNG LLSIELDDIG SDPDIDALLV NSPFFHDLFP SPVCEEIEST SMEGKSKENE  480
GQAMDDGWDK YQHMDKLTEQ MGLLRSENKG I
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5d5u_B2e-293013412129Heat shock factor protein 1
5d5v_B2e-293013412129Heat shock factor protein 1
5d5v_D2e-293013412129Heat shock factor protein 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1246253NKKRRLKQ
2247252KKRRLK
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Ghi.34280.0boll| ovule
Functional Description ? help Back to Top
Source Description
UniProtDNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. {ECO:0000250}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKR0674060.0KR067406.1 Gossypium hirsutum HSF25 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016736699.10.0PREDICTED: heat shock factor protein HSF8-like isoform X1
SwissprotQ401520.0HSF8_SOLLC; Heat shock factor protein HSF8
TrEMBLA0A1U8NFU50.0A0A1U8NFU5_GOSHI; heat shock factor protein HSF8-like isoform X1
STRINGGorai.008G225200.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM64702440
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G32330.11e-126heat shock transcription factor A1D
Publications ? help Back to Top
  1. Zhu B, et al.
    Identification and characterization of a novel heat shock transcription factor gene, GmHsfA1, in soybeans (Glycine max).
    J. Plant Res., 2006. 119(3): p. 247-56
    [PMID:16570125]
  2. Wang J,Sun N,Deng T,Zhang L,Zuo K
    Genome-wide cloning, identification, classification and functional analysis of cotton heat shock transcription factors in cotton (Gossypium hirsutum).
    BMC Genomics, 2014. 15: p. 961
    [PMID:25378022]
  3. Cai SY, et al.
    HsfA1a upregulates melatonin biosynthesis to confer cadmium tolerance in tomato plants.
    J. Pineal Res., 2017.
    [PMID:28095626]
  4. Zhou J, et al.
    Heat Shock Factor HsfA1a Is Essential for R Gene-Mediated Nematode Resistance and Triggers H2O2 Production1.
    Plant Physiol., 2018. 176(3): p. 2456-2471
    [PMID:29339397]