PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

ERF

Protein Properties

Length: 235aa MW: 26018.4 Da PI: 9.3805

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_A12G1761	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	61.2	2.3e-19	54	103	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 +y+GVr+++ +g+W+AeIrdp+ + +r++lg+f tae Aa a++ a+++++g Gh_A12G1761 54 HYRGVRQRP-WGKWAAEIRDPK----KaARVWLGTFETAEAAALAYDDAALRFKG 103 7******.******94....45*********************9987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.730.10	8.9E-33	53	112	IPR001471	AP2/ERF domain
SMART	SM00380	3.4E-37	54	117	IPR001471	AP2/ERF domain
CDD	cd00018	2.27E-19	54	112	No hit	No description
Pfam	PF00847	3.2E-13	54	103	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	6.54E-22	54	112	IPR016177	DNA-binding domain
PROSITE profile	PS51032	24.935	54	111	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.4E-11	55	66	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.4E-11	77	93	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 235 aa Download sequence Send to blast
MNAMVHALAQ VIGNNNSNPL LQLHDDQHPN PTAQQNQSHQ QPQPQDQGNA RRRHYRGVRQ 60 RPWGKWAAEI RDPKKAARVW LGTFETAEAA ALAYDDAALR FKGSKAKLNF PERVQGRLES 120 SYLTTTRQEL ERTEAPPHPP PTYPNISQYA QLLSGGLPNT AFNYAMPSGA AYGSWPAFTT 180 NSHSASSSSS SSSTTLTSQQ QGYMGGFSLH FGGSSPTSDH TNNMGDYDYY YSRDR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2gcc_A	2e-27	50	114	1	66	ATERF1
3gcc_A	2e-27	50	114	1	66	ATERF1
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed during the S phase of the cell cycle. {ECO:0000269\|PubMed:23616605}.
Uniprot	TISSUE SPECIFICITY: Strongly expressed in proliferating cells. Detected in root tips, stipules, shoot apex, floral tissues, young siliques and abscission zones. {ECO:0000269\|PubMed:23616605}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator of cell proliferation and axillary bud outgrowth. Involved in maintaining the structure of the shoot apical meristem as well as plastochron and phyllotaxy. Activates several genes involved in cell cycle regulation and dormancy breaking, including CYCD3-3, DPA, and BARD1. Strongly down-regulates DRM1, DRMH1, MARD1 and several genes encoding different types of cell wall-remodeling proteins. {ECO:0000269\|PubMed:23616605}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Transiently up-regulated 6 to 15 hours after decapitation. {ECO:0000269\|PubMed:23616605}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	JX589428	3e-73	JX589428.1 Gossypium hirsutum clone NBRI_GE24128 microsatellite sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016736869.1	1e-175	PREDICTED: ethylene-responsive transcription factor ERF114-like
Swissprot	Q9FH54	6e-51	EF114_ARATH; Ethylene-responsive transcription factor ERF114
TrEMBL	A0A1U8NGD8	1e-173	A0A1U8NGD8_GOSHI; ethylene-responsive transcription factor ERF114-like
STRING	Gorai.008G210600.1	1e-122	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM22135	4	5

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G61890.1	4e-34	ERF family protein

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kong X, et al. PHB3 Maintains Root Stem Cell Niche Identity through ROS-Responsive AP2/ERF Transcription Factors in Arabidopsis. Cell Rep, 2018. 22(5): p. 1350-1363 [PMID:29386120]