PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

bHLH

Protein Properties

Length: 679aa MW: 75979.8 Da PI: 4.7967

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_A08G2365	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	38.7	1.8e-12	480	526	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h +ErrR +++N++f Lr+l+P +K++Ka+iL ++eY+k+L+ Gh_A08G2365 480 NHVLAERRRSEKLNERFIILRSLVPFV-----TKMDKASILGDTIEYVKQLR 526 7999********************8.....8***************95 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF14215	1.7E-52	9	186	IPR025610	Transcription factor MYC/MYB N-terminal
PROSITE profile	PS50888	16.596	476	525	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	5.5E-18	476	544	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	4.50E-13	480	530	No hit	No description
Gene3D	G3DSA:4.10.280.10	7.3E-18	480	542	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	4.9E-10	480	525	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	2.7E-15	482	531	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 679 aa Download sequence Send to blast
MAAPPSSRLQ KMLQAAVQSV QWTYSLFWQI CPQQGILIWS DGYYNGAIKT RKTVQPMEVS 60 TEEASLQRSQ QLRELYDSLS SGDTNQPARR PSAALSPEDL TESEWFYLMC VSFSFPPGVG 120 LPGKAYARRQ HVWLTGANEV DSKTFSRAIL AKTVLCIPIL DGVLELGYTE KVQEDLGLVQ 180 HVKTFFNDGQ APNPPPPKPA LSEHSTSNPA ASSDYTRFHS PSVPLVYAAA DPPVTADQGE 240 NNNVDEEEEE EEDDDDEEGD EEPESYSAET GRNTQQVPTE NTLAVVAAEE PSELMQLDMS 300 EDIKLGSPDD ASNNLDSDFN MLAVSQSGNP TVNQRRAALF RDESNRRWQM LQEPSCSSLQ 360 PLSTGPQPMD EMSQEDTHYS QTVSTILQAQ PARWTEPPST VNAATYSTQS AFAKWTTHSD 420 HHLHSAVVEG TSQWLLKYIL FTVPFLHNKY RDENSPKSRD AVAAAARFRK GTPNEDLSAN 480 HVLAERRRSE KLNERFIILR SLVPFVTKMD KASILGDTIE YVKQLRKKIQ DLETRNKQME 540 ADNDRPRSAD SMQRNSSSKD QRSGLTTRSS GPDKKKMRIA EATKQKTVEP PPQTEETSVE 600 VSIIESDALL ELQCGYREGL LLDIMQMLRE KLRIEITAVQ SSLNNGFFTA ELRAKVKDNM 660 NGKKVSIMEV KRAINQIIP

Sequence ? help Back to Top

Protein Sequence Length: 679 aa Download sequence Send to blast

MAAPPSSRLQ KMLQAAVQSV QWTYSLFWQI CPQQGILIWS DGYYNGAIKT RKTVQPMEVS  60
TEEASLQRSQ QLRELYDSLS SGDTNQPARR PSAALSPEDL TESEWFYLMC VSFSFPPGVG  120
LPGKAYARRQ HVWLTGANEV DSKTFSRAIL AKTVLCIPIL DGVLELGYTE KVQEDLGLVQ  180
HVKTFFNDGQ APNPPPPKPA LSEHSTSNPA ASSDYTRFHS PSVPLVYAAA DPPVTADQGE  240
NNNVDEEEEE EEDDDDEEGD EEPESYSAET GRNTQQVPTE NTLAVVAAEE PSELMQLDMS  300
EDIKLGSPDD ASNNLDSDFN MLAVSQSGNP TVNQRRAALF RDESNRRWQM LQEPSCSSLQ  360
PLSTGPQPMD EMSQEDTHYS QTVSTILQAQ PARWTEPPST VNAATYSTQS AFAKWTTHSD  420
HHLHSAVVEG TSQWLLKYIL FTVPFLHNKY RDENSPKSRD AVAAAARFRK GTPNEDLSAN  480
HVLAERRRSE KLNERFIILR SLVPFVTKMD KASILGDTIE YVKQLRKKIQ DLETRNKQME  540
ADNDRPRSAD SMQRNSSSKD QRSGLTTRSS GPDKKKMRIA EATKQKTVEP PPQTEETSVE  600
VSIIESDALL ELQCGYREGL LLDIMQMLRE KLRIEITAVQ SSLNNGFFTA ELRAKVKDNM  660
NGKKVSIMEV KRAINQIIP

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4rqw_A	3e-21	9	187	9	193	Transcription factor MYC3
4rqw_B	3e-21	9	187	9	193	Transcription factor MYC3
4rs9_A	3e-21	9	187	9	193	Transcription factor MYC3
4yz6_A	3e-21	9	187	9	193	Transcription factor MYC3
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Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Ghi.9746	0.0	ovule

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the control of flavonoid pigmentation. {ECO:0000269\|PubMed:20949001}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KP698861	0.0	KP698861.1 Gossypium hirsutum basic helix-loop-helix protein 064A (bHLH064A) gene, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017623495.1	0.0	PREDICTED: basic helix-loop-helix protein A-like
Swissprot	E3SXU4	0.0	BHLHW_PEA; Basic helix-loop-helix protein A
TrEMBL	A0A0G2US55	0.0	A0A0G2US55_GOSHI; Basic helix-loop-helix protein 064A
STRING	Gorai.004G215900.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM9422	28	36

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G09820.1	7e-91	bHLH family protein

Publications ? help Back to Top
Hellens RP, et al. Identification of Mendel's white flower character. PLoS ONE, 2010. 5(10): p. e13230 [PMID:20949001] Yan Q, et al. The Basic/Helix-Loop-Helix Protein Family in Gossypium: Reference Genes and Their Evolution during Tetraploidization. PLoS ONE, 2015. 10(5): p. e0126558 [PMID:25992947]