PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

HSF

Protein Properties

Length: 503aa MW: 55489.7 Da PI: 5.7894

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_A08G2299	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	112.4	3.2e-35	25	116	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 Fl+k+y++++d+++++++sws+ +nsfvv++ efa+++LpkyFkh+nf+SFvRQLn+YgF+kv+ ++ weF+++ F +g+k+ll++i Gh_A08G2299 25 FLSKTYDVVNDPSTDSVVSWSSGNNSFVVWKVPEFARDLLPKYFKHNNFSSFVRQLNTYGFRKVDPDR---------WEFANEGFLRGQKHLLKTIS 112 9**************************************************************999.........****************** PP XXXX CS HSF_DNA-bind 99 rkks 102 r+k Gh_A08G2299 113 RRKP 116 *985 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	2.1E-38	15	109	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	3.67E-34	20	114	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	2.1E-59	21	114	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Pfam	PF00447	9.1E-31	25	114	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	1.5E-19	25	48	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	1.5E-19	63	75	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	64	88	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	1.5E-19	76	88	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 503 aa Download sequence Send to blast
MDSLHDSISA ANAAATANGN TVPPFLSKTY DVVNDPSTDS VVSWSSGNNS FVVWKVPEFA 60 RDLLPKYFKH NNFSSFVRQL NTYGFRKVDP DRWEFANEGF LRGQKHLLKT ISRRKPPNVQ 120 SNQQPQVQNS SVGACIEVGK FGLEEEVERL KRDKNVLMQE LVRLRQQQQT TDSQLQTVGQ 180 RVQVMEQRQQ QMMSFLAKAM QSPSFLGQLV QQQNESNRRI TGANKKRRLP RQDEENLAGE 240 NGAVSAKGQI VKFQPSLNEA AKAMLHQIMK MNTSPRLDPS INNSGSFLID GVPPSNAPDS 300 RSSSSRISGV TLSEVQPASA RSYLQAESGF PDTCLSAAAH LTSDHTNADQ ISRINEHKSQ 360 KHGVIPNVSQ MQGTMPDGTV GLTDRSLAGS ERGSAEYLDP LLDVLDGTMP VETDDFSADH 420 DMDILLNGSP ELPAINDVFW EKFLATSPLT GDTDEISSSS LENGANLEQQ QAPVRQESGW 480 DGIHHMNHLT EQMGLLSSNG QTR

Sequence ? help Back to Top

Protein Sequence Length: 503 aa Download sequence Send to blast

MDSLHDSISA ANAAATANGN TVPPFLSKTY DVVNDPSTDS VVSWSSGNNS FVVWKVPEFA  60
RDLLPKYFKH NNFSSFVRQL NTYGFRKVDP DRWEFANEGF LRGQKHLLKT ISRRKPPNVQ  120
SNQQPQVQNS SVGACIEVGK FGLEEEVERL KRDKNVLMQE LVRLRQQQQT TDSQLQTVGQ  180
RVQVMEQRQQ QMMSFLAKAM QSPSFLGQLV QQQNESNRRI TGANKKRRLP RQDEENLAGE  240
NGAVSAKGQI VKFQPSLNEA AKAMLHQIMK MNTSPRLDPS INNSGSFLID GVPPSNAPDS  300
RSSSSRISGV TLSEVQPASA RSYLQAESGF PDTCLSAAAH LTSDHTNADQ ISRINEHKSQ  360
KHGVIPNVSQ MQGTMPDGTV GLTDRSLAGS ERGSAEYLDP LLDVLDGTMP VETDDFSADH  420
DMDILLNGSP ELPAINDVFW EKFLATSPLT GDTDEISSSS LENGANLEQQ QAPVRQESGW  480
DGIHHMNHLT EQMGLLSSNG QTR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	7e-27	15	114	19	129	Heat shock factor protein 1
5d5v_B	7e-27	15	114	19	129	Heat shock factor protein 1
5d5v_D	7e-27	15	114	19	129	Heat shock factor protein 1
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Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Ghi.2764	0.0	boll\| ovule

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: DNA-binding capacity is reduced by HSBP in vitro. {ECO:0000269\|PubMed:20388662}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KJ702452	0.0	KJ702452.1 Gossypium hirsutum heat shock transcription factor (HSF10) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016729185.1	0.0	PREDICTED: heat stress transcription factor A-1e-like
Swissprot	O81821	1e-163	HFA1B_ARATH; Heat stress transcription factor A-1b
TrEMBL	A0A2P5X6P6	0.0	A0A2P5X6P6_GOSBA; Uncharacterized protein
STRING	Gorai.004G257000.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2236	23	71

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G16820.2	1e-139	heat shock factor 3

Publications ? help Back to Top
Hsu SF,Jinn TL AtHSBP functions in seed development and the motif is required for subcellular localization and interaction with AtHSFs. Plant Signal Behav, 2010. 5(8): p. 1042-4 [PMID:20657173] Bechtold U, et al. Arabidopsis HEAT SHOCK TRANSCRIPTION FACTORA1b overexpression enhances water productivity, resistance to drought, and infection. J. Exp. Bot., 2013. 64(11): p. 3467-81 [PMID:23828547] Guan Q,Yue X,Zeng H,Zhu J The protein phosphatase RCF2 and its interacting partner NAC019 are critical for heat stress-responsive gene regulation and thermotolerance in Arabidopsis. Plant Cell, 2014. 26(1): p. 438-53 [PMID:24415771]