PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gh_A05G2341
Organism
Gossypium hirsutum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family C2H2
Protein Properties Length: 359aa    MW: 41166.9 Da    PI: 8.3322
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gh_A05G2341genomeNAU-NBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H219.82.1e-066081223
                 EETTTTEEESSHHHHHHHHHHT CS
      zf-C2H2  2 kCpdCgksFsrksnLkrHirtH 23
                 +C+ Cg sF+ + +Lk+H+++H
  Gh_A05G2341 60 TCEECGASFKKPAYLKQHLQSH 81
                 6*******************99 PP
2zf-C2H217.21.4e-0587111123
                  EEET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                  ++C+  dC+ s++rk++L+rH+  H
  Gh_A05G2341  87 FVCSveDCHASYRRKDHLNRHLLQH 111
                  89*******************9887 PP
3zf-C2H214.88.2e-05116141123
                  EEET..TTTEEESSHHHHHHHHHH.T CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                  +kC   +C++ F  + n+krHi+  H
  Gh_A05G2341 116 FKCLieNCNREFAFQGNMKRHIKEfH 141
                  799999*****************988 PP
4zf-C2H217.41.3e-05156180123
                  EEET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                  y+C+   Cgk+F   s Lk+H  +H
  Gh_A05G2341 156 YVCQevGCGKVFEFASKLKKHEDSH 180
                  99*******************9888 PP
5zf-C2H217.51.1e-05248272223
                  EET..TTTEEESSHHHHHHHHHH.T CS
      zf-C2H2   2 kCp..dCgksFsrksnLkrHirt.H 23 
                  kC    C  +Fs+ksnL++Hi+  H
  Gh_A05G2341 248 KCDfeGCLHTFSTKSNLRQHIKAvH 272
                  688889***************9888 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM00355201840IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015713.365986IPR007087Zinc finger, C2H2
SMARTSM003550.0145981IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.606.4E-76080IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576675.14E-1060111No hitNo description
PROSITE patternPS0002806181IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.607.3E-1281113IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.55687116IPR007087Zinc finger, C2H2
SMARTSM003550.006587111IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028089111IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.605.9E-5114143IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576673.47E-6114142No hitNo description
PROSITE profilePS5015710.658116146IPR007087Zinc finger, C2H2
SMARTSM003550.083116141IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280118141IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.0E-7152180IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576677.72E-5153180No hitNo description
PROSITE profilePS5015710.824156185IPR007087Zinc finger, C2H2
SMARTSM003550.019156180IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280158180IPR007087Zinc finger, C2H2
SMARTSM003550.6188213IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280190213IPR007087Zinc finger, C2H2
SMARTSM0035518216237IPR015880Zinc finger, C2H2-like
SuperFamilySSF576672.88E-8229285No hitNo description
PROSITE profilePS5015711.676247277IPR007087Zinc finger, C2H2
SMARTSM003550.0018247272IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.603.7E-6248272IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280249272IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.604.0E-4273300IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003558.7278304IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280280304IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 359 aa     Download sequence    Send to blast
MEEEKKVGGA IFKDIRRYYC EFCGICRSKK SLINSHILTH HTDEVNKRGK EEEGASSSNT  60
CEECGASFKK PAYLKQHLQS HSLERPFVCS VEDCHASYRR KDHLNRHLLQ HQGKLFKCLI  120
ENCNREFAFQ GNMKRHIKEF HDEESSDLDA GSQKQYVCQE VGCGKVFEFA SKLKKHEDSH  180
VKLDSLEAFC SEPGCMKYFT NEQCLKAHVQ SSHAYINCQI CGAKQLKKNI KRHLRSHEPG  240
GVESERIKCD FEGCLHTFST KSNLRQHIKA VHEELKPFAC SFFGCGMRFS YKHVRDNHEK  300
SGCHVYTPGN FLETDEQFCS KPRGGRKRTC PTVEMLVRKR VTPPQMDAMM DLGPSPACS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1tf6_A1e-166321519162PROTEIN (TRANSCRIPTION FACTOR IIIA)
1tf6_D1e-166321519162PROTEIN (TRANSCRIPTION FACTOR IIIA)
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Ghi.144210.0ovule
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Both isoforms 1 and 2 transcripts are expressed in seedlings and both TFIIIA and TFIIIA-C are present at similar ratios in 10-day-old seedlings (at protein level). In correlation with the reorganization of 5S rDNA chromatin to a mature state, full-length isoform 1 protein TFIIIA with transcriptional activity accumulates and permits de novo transcription of 5S rRNA. Isoforms 1 and 2 transcripts accumulate in various tissues of the reproductive phase, including flowers and siliques, but only isoform 2 is present in mature seeds. In flowers, both TFIIIA and TFIIIA-C are present at similar ratios (at protein level). Very low amounts of TFIIIA are found in extracts from fresh siliques compared to TFIIIA-C. The amount of full-length TFIIIA protein progressively increases from fresh siliques to seeds concomitant with lower proportions of the shorter TFIIIA-C protein (at protein level) thus leading to 5S rRNA accumulation in the seed. {ECO:0000269|PubMed:22353599}.
UniprotTISSUE SPECIFICITY: Expressed in seedlings, flowers, siliques and seeds. {ECO:0000269|PubMed:22353599}.
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (PubMed:22353599). Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599). Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599). {ECO:0000269|PubMed:12711688, ECO:0000269|PubMed:22353599}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016748492.10.0PREDICTED: transcription factor IIIA-like isoform X1
SwissprotQ84MZ41e-149TF3A_ARATH; Transcription factor IIIA
TrEMBLA0A1U8PBC80.0A0A1U8PBC8_GOSHI; transcription factor IIIA-like isoform X1
STRINGGorai.009G288800.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM47142852
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G72050.21e-151transcription factor IIIA