PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gh_A03G0276
Organism
Gossypium hirsutum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family HD-ZIP
Protein Properties Length: 845aa    MW: 92738.7 Da    PI: 6.1091
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gh_A03G0276genomeNAU-NBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox57.42.5e-182785357
                 --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
     Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
                 k  ++t+eq+e+Le++++++++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  Gh_A03G0276 27 KYVRYTAEQVEALERVYAECPKPSSLRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 85
                 56789****************************************************97 PP
2START155.44.7e-491663742205
                  HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EEEEEEEEX CS
        START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..galqlmvae 97 
                  +aee+++e+++ka+ ++  Wv+++ +++g++ + +f+ s+++sg a+ra+g+v  +++   +e+l+d++ W ++++  e+      g  g+++l +++
  Gh_A03G0276 166 IAEETLAEFLSKATGTAVDWVQMPGMKPGPDLVGIFAISQSCSGVAARACGLVSLEPT-KIAEILKDRPSWLRDCRNLEVFTMFPAGsgGTIELVYTQ 262
                  7899******************************************************.7777777777*******9999999999888********* PP

                  XTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHHHHHHHHHH CS
        START  98 lqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrslvksglae 191
                  + a+++l+p Rdf+++Ry+ +l+ g++v++++S++     p+    +++vRae+lpSg+li+p+++g+s +++v+h +l+++ ++++lr+l++s+ + 
  Gh_A03G0276 263 MFAPTTLAPaRDFWTLRYTTTLENGSFVVCERSLSGSGAGPStaaAAQFVRAEVLPSGYLIRPCEGGGSIIHIVDHLNLEAWNVPEVLRPLYESSKVI 360
                  ***********************************88888877999**************************************************** PP

                  HHHHHHHHTXXXXX CS
        START 192 gaktwvatlqrqce 205
                  ++k++ a+l++ ++
  Gh_A03G0276 361 AQKMTIAALRYVKQ 374
                  *********99876 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007115.3372286IPR001356Homeobox domain
SuperFamilySSF466892.18E-162388IPR009057Homeodomain-like
SMARTSM003891.7E-152490IPR001356Homeobox domain
CDDcd000864.82E-162787No hitNo description
PfamPF000467.5E-162885IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.603.0E-182985IPR009057Homeodomain-like
CDDcd146864.89E-679118No hitNo description
PROSITE profilePS5084827.25156384IPR002913START domain
CDDcd088751.66E-67160376No hitNo description
SuperFamilySSF559612.88E-33165377No hitNo description
SMARTSM002348.9E-40165375IPR002913START domain
Gene3DG3DSA:3.30.530.201.3E-19165370IPR023393START-like domain
PfamPF018529.6E-47166374IPR002913START domain
SuperFamilySSF559612.88E-5406500No hitNo description
SuperFamilySSF559612.88E-5535602No hitNo description
PfamPF086702.1E-49701844IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009855Biological Processdetermination of bilateral symmetry
GO:0009944Biological Processpolarity specification of adaxial/abaxial axis
GO:0009956Biological Processradial pattern formation
GO:0010014Biological Processmeristem initiation
GO:0010051Biological Processxylem and phloem pattern formation
GO:0010089Biological Processxylem development
GO:0030154Biological Processcell differentiation
GO:0005634Cellular Componentnucleus
GO:0008289Molecular Functionlipid binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 845 aa     Download sequence    Send to blast
MAMAVAQHRV STSGSSSINK HLDASGKYVR YTAEQVEALE RVYAECPKPS SLRRQQLIRE  60
CPILSNIEPK QIKVWFQNRR CREKQRKESS RLQTVNRKLS AMNKLLMEEN DRLQKQVSQL  120
VCENGYMRQQ LHTVNASATD ASCDSVVTTP QHSLRDPNNP AGLLSIAEET LAEFLSKATG  180
TAVDWVQMPG MKPGPDLVGI FAISQSCSGV AARACGLVSL EPTKIAEILK DRPSWLRDCR  240
NLEVFTMFPA GSGGTIELVY TQMFAPTTLA PARDFWTLRY TTTLENGSFV VCERSLSGSG  300
AGPSTAAAAQ FVRAEVLPSG YLIRPCEGGG SIIHIVDHLN LEAWNVPEVL RPLYESSKVI  360
AQKMTIAALR YVKQIAQETS GEVVYSMGRQ PAVLRTFSQR LSRGFNDAIN GFNDDGWSIM  420
NCDGNEDVII AINSSKSFSC TSNPNNALPF VGGVLCAKAS MLLQNVPPAV LVRFLREHRS  480
EWADFNVDAY TAASLKAGTY AYPGMRPTRF TGSQIIMPLG HTIEHEEILE VIRLEGHSLV  540
QEDAFVSRDI HLLQICSGID ENAVGACSEL VFAPIDEMFP DDAPLIPSGF RIIPLESKPS  600
DTKDSLTTNR TLDLTSSLEV GPATNHSSGD VPSSQNSRSV LTIAFQFPFD SSLQDNVATM  660
ARQYVRSVIS SVQRVAMAIS PSGLSMAVGP KLSPGSPEAL TLAQWIYQSY SYHIGAELLR  720
SESLGSDSIL KNLWQHQDAI LCCSLKSLPV FIFANQAGLD MLETTLVSLQ DITLDKIFDE  780
PGRKALCSDF AKLMQQGYAY FPAGICMSTM GRHVSYEQAV AWKVLEADES TVHCLAFSFV  840
NWSFV
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Ghi.136630.0ovule
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed at the earliest stages and throughout LSM initiation and development. In embryo development, expressed at the heart stage until the 'walking stick' stage in the adaxial portion of the cotyledon primordia, the shoot apical meristem (SAM) and the vascular precursor cells of the hypocotyl and root. In developing flowers, expressed first at stage 1 in the center of L3 layer and then expands to the center of L2 and L1 layers. Expressed in the center of flower meristem through stages 4 and 5. At stage 6, expressed in the adaxial side of the carpel primordia and then on the adaxial carpel face. {ECO:0000269|PubMed:11169198}.
UniprotTISSUE SPECIFICITY: Expressed in the interfascicular regions of stem and vascular bundles of young roots and leaves. {ECO:0000269|PubMed:10559440}.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of interfascicular fiber (cortical cells) and secondary xylem differentiation in the inflorescence stems. Required for lateral shoot meristems (LSMs) and flower meristems (FMs) initiation. May be involved in the determination of vascular patterning and organ polarity (PubMed:10559440, PubMed:11169198, PubMed:11402186, PubMed:15111711, PubMed:15598805, PubMed:7555701). Directly regulates the expression of AGO10, ZPR1, ZPR2, ZPR3 and ZPR4 (PubMed:22781836). Required to regulate adaxial-abaxial polarity and leaf axial patterning (PubMed:20807212). {ECO:0000269|PubMed:10559440, ECO:0000269|PubMed:11169198, ECO:0000269|PubMed:11402186, ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:15598805, ECO:0000269|PubMed:20807212, ECO:0000269|PubMed:22781836, ECO:0000269|PubMed:7555701}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by ZPR and miR165. Induced by DOF5.1 (PubMed:20807212). {ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:17237362, ECO:0000269|PubMed:20807212}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016755877.10.0PREDICTED: homeobox-leucine zipper protein REVOLUTA-like isoform X2
SwissprotQ9SE430.0REV_ARATH; Homeobox-leucine zipper protein REVOLUTA
TrEMBLA0A1U8PXK70.0A0A1U8PXK7_GOSHI; homeobox-leucine zipper protein REVOLUTA-like isoform X2
STRINGGorai.003G142200.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM47792754
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G60690.10.0HD-ZIP family protein
Publications ? help Back to Top
  1. Lian H,Li X,Liu Z,He Y
    HYL1 is required for establishment of stamen architecture with four microsporangia in Arabidopsis.
    J. Exp. Bot., 2013. 64(11): p. 3397-410
    [PMID:23918970]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Baima S, et al.
    Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module.
    Mol Plant, 2014. 7(6): p. 1006-1025
    [PMID:24777988]
  4. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  5. Roodbarkelari F,Du F,Truernit E,Laux T
    ZLL/AGO10 maintains shoot meristem stem cells during Arabidopsis embryogenesis by down-regulating ARF2-mediated auxin response.
    BMC Biol., 2015. 13: p. 74
    [PMID:26358077]
  6. Shi B, et al.
    Two-Step Regulation of a Meristematic Cell Population Acting in Shoot Branching in Arabidopsis.
    PLoS Genet., 2016. 12(7): p. e1006168
    [PMID:27398935]