PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Gh_A01G0217

Organism

Gossypium hirsutum

Taxonomic ID

3635

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

ARR-B

Protein Properties

Length: 678aa MW: 74794 Da PI: 6.0179

Description

ARR-B family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_A01G0217	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	G2-like	90.9	1.1e-28	216	269	1	55
G2-like 1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 kpr++W+ eLH++Fv av+qL G++kA+Pk+ilelm+v+gLt+e+v+SHLQkYRl Gh_A01G0217 216 KPRVVWSIELHQQFVAAVNQL-GIDKAVPKKILELMNVPGLTRENVASHLQKYRL 269 79*****************.******************************8 PP
2	Response_reg	75.2	2.5e-25	38	146	1	109
EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHHHHTTES CS Response_reg 1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalealkaGak 95 vl+vdD+p+ + +l+++l++ y +v+ + +e al +l+e++ +D+i+ D+ mp+mdG++ll++i e +lp+i+++a + ++ + + + Ga Gh_A01G0217 38 VLVVDDDPTCLIILEKMLRNCSY-DVTKCNRAETALLKLRENRngFDIIISDVHMPDMDGFKLLEHIGLEM-DLPVIMMSADDGKDVVMKGVTHGAC 132 89*******************.***********99999*******************6654.8******************** PP EEEESS--HHHHHH CS Response_reg 96 dflsKpfdpeelvk 109 d+l Kp+ +e+l + Gh_A01G0217 133 DYLIKPVRIEALKN 146 ********9986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PIRSF	PIRSF036392	1.5E-173	12	670	IPR017053	Response regulator B-type, plant
Gene3D	G3DSA:3.40.50.2300	1.5E-41	35	174	No hit	No description
SuperFamily	SSF52172	1.71E-35	35	160	IPR011006	CheY-like superfamily
SMART	SM00448	2.1E-29	36	148	IPR001789	Signal transduction response regulator, receiver domain
PROSITE profile	PS50110	42.177	37	152	IPR001789	Signal transduction response regulator, receiver domain
Pfam	PF00072	1.7E-22	38	146	IPR001789	Signal transduction response regulator, receiver domain
CDD	cd00156	3.14E-26	39	151	No hit	No description
SuperFamily	SSF46689	5.38E-20	213	273	IPR009057	Homeodomain-like
PROSITE profile	PS51294	10.775	213	272	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	5.2E-30	215	274	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	1.3E-24	216	269	IPR006447	Myb domain, plants
Pfam	PF00249	3.4E-7	218	268	IPR001005	SANT/Myb domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0000160	Biological Process	phosphorelay signal transduction system
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 678 aa Download sequence Send to blast
MKNSIGGKGS MSTASSITTW KAGDVVSVPD QFPAGLRVLV VDDDPTCLII LEKMLRNCSY 60 DVTKCNRAET ALLKLRENRN GFDIIISDVH MPDMDGFKLL EHIGLEMDLP VIMMSADDGK 120 DVVMKGVTHG ACDYLIKPVR IEALKNIWQH VVRKRKNEWK DLEQSGSVEE GDRQPKQSED 180 ADYSSSVNEG NWKSSKKRKD DEDETDDRDD TSTLKKPRVV WSIELHQQFV AAVNQLGIDK 240 AVPKKILELM NVPGLTRENV ASHLQKYRLY LRRLSGVSPH SCNPNNSFMN PQDETFGPLS 300 SVHGFDLQTL TATGQLPAQC LATLQAAVLG RSTAKSSIPM PLVNQRNIFS FENPKLRFGE 360 GQQQHVNNNN KQVNLLHGIP TTMESKQLTS LRHTSQSIGN LNMQVAPHGA QSRQNNSSLI 420 EMGQPLSRVQ ILNDSTVPLS VGQPIVPNGI AANVSTRNGI PENIRAPGYN LVSQTSSILN 480 FPMNHASELP VDTFSLRSTP GMSDHTSKGA FHEDFNSEIK GSGGFLPSYD VFNDYQYKSQ 540 NWELQNAGMI LDDSQHSNSL QGNLDLTQSV LVQQGFPSGQ INGQNRSVPI VSKAMFSAGD 600 STEPGNLLNV NHHLNTIRAD NTVRVKSESV ADGNPSNLFT DHFGQEDLMI ALLKQQQGIA 660 PVENEFDFDG YSLDNIPV

Sequence ? help Back to Top

Protein Sequence Length: 678 aa Download sequence Send to blast

MKNSIGGKGS MSTASSITTW KAGDVVSVPD QFPAGLRVLV VDDDPTCLII LEKMLRNCSY  60
DVTKCNRAET ALLKLRENRN GFDIIISDVH MPDMDGFKLL EHIGLEMDLP VIMMSADDGK  120
DVVMKGVTHG ACDYLIKPVR IEALKNIWQH VVRKRKNEWK DLEQSGSVEE GDRQPKQSED  180
ADYSSSVNEG NWKSSKKRKD DEDETDDRDD TSTLKKPRVV WSIELHQQFV AAVNQLGIDK  240
AVPKKILELM NVPGLTRENV ASHLQKYRLY LRRLSGVSPH SCNPNNSFMN PQDETFGPLS  300
SVHGFDLQTL TATGQLPAQC LATLQAAVLG RSTAKSSIPM PLVNQRNIFS FENPKLRFGE  360
GQQQHVNNNN KQVNLLHGIP TTMESKQLTS LRHTSQSIGN LNMQVAPHGA QSRQNNSSLI  420
EMGQPLSRVQ ILNDSTVPLS VGQPIVPNGI AANVSTRNGI PENIRAPGYN LVSQTSSILN  480
FPMNHASELP VDTFSLRSTP GMSDHTSKGA FHEDFNSEIK GSGGFLPSYD VFNDYQYKSQ  540
NWELQNAGMI LDDSQHSNSL QGNLDLTQSV LVQQGFPSGQ INGQNRSVPI VSKAMFSAGD  600
STEPGNLLNV NHHLNTIRAD NTVRVKSESV ADGNPSNLFT DHFGQEDLMI ALLKQQQGIA  660
PVENEFDFDG YSLDNIPV

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1irz_A	5e-22	215	275	4	64	ARR10-B
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Ghi.22703	0.0	boll

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed only from 5 days post germination onward, when the fixed meristem cell number is established. {ECO:0000269\|PubMed:17363254}.
Uniprot	TISSUE SPECIFICITY: Detected in the whole plant. Expressed at the root transition zone (PubMed:17363254). {ECO:0000269\|PubMed:15173562, ECO:0000269\|PubMed:17363254, ECO:0000269\|PubMed:9891419}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Regulates SHY2 by binding to its promoter (PubMed:19039136). Involved in the root-meristem size determination through the regulation of cell differentiation (PubMed:17363254). {ECO:0000269\|PubMed:11574878, ECO:0000269\|PubMed:11691951, ECO:0000269\|PubMed:17363254, ECO:0000269\|PubMed:19039136}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated by gibberellin. {ECO:0000269\|PubMed:20605455}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017642772.1	0.0	PREDICTED: two-component response regulator ARR2
Swissprot	Q940D0	0.0	ARR1_ARATH; Two-component response regulator ARR1
TrEMBL	A0A0B0M7N9	0.0	A0A0B0M7N9_GOSAR; Two-component response regulator
STRING	Gorai.002G029200.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2403	27	73

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G16857.2	0.0	response regulator 1

Publications ? help Back to Top
Bürkle L,Meyer S,Dortay H,Lehrach H,Heyl A In vitro recombination cloning of entire cDNA libraries in Arabidopsis thaliana and its application to the yeast two-hybrid system. Funct. Integr. Genomics, 2005. 5(3): p. 175-83 [PMID:15714319] Moubayidin L, et al. Spatial coordination between stem cell activity and cell differentiation in the root meristem. Dev. Cell, 2013. 26(4): p. 405-15 [PMID:23987513] Takahashi N, et al. Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots. Curr. Biol., 2013. 23(18): p. 1812-7 [PMID:24035544] Kurepa J,Li Y,Perry SE,Smalle JA Ectopic expression of the phosphomimic mutant version of Arabidopsis response regulator 1 promotes a constitutive cytokinin response phenotype. BMC Plant Biol., 2014. 14: p. 28 [PMID:24423196] Cortleven A, et al. A novel protective function for cytokinin in the light stress response is mediated by the Arabidopsis histidine kinase2 and Arabidopsis histidine kinase3 receptors. Plant Physiol., 2014. 164(3): p. 1470-83 [PMID:24424319] Marín-de la Rosa N, et al. Genome Wide Binding Site Analysis Reveals Transcriptional Coactivation of Cytokinin-Responsive Genes by DELLA Proteins. PLoS Genet., 2015. 11(7): p. e1005337 [PMID:26134422] D'Alessandro S,Golin S,Hardtke CS,Lo Schiavo F,Zottini M The co-chaperone p23 controls root development through the modulation of auxin distribution in the Arabidopsis root meristem. J. Exp. Bot., 2015. 66(16): p. 5113-22 [PMID:26163704] Jiang L, et al. Strigolactones spatially influence lateral root development through the cytokinin signaling network. J. Exp. Bot., 2016. 67(1): p. 379-89 [PMID:26519957] Moubayidin L, et al. A SCARECROW-based regulatory circuit controls Arabidopsis thaliana meristem size from the root endodermis. Planta, 2016. 243(5): p. 1159-68 [PMID:26848984] Muraro D, et al. A multi-scale model of the interplay between cell signalling and hormone transport in specifying the root meristem of Arabidopsis thaliana. J. Theor. Biol., 2016. 404: p. 182-205 [PMID:27157127] Cortleven A, et al. Cytokinin Regulates the Etioplast-Chloroplast Transition through the Two-Component Signaling System and Activation of Chloroplast-Related Genes. Plant Physiol., 2016. 172(1): p. 464-78 [PMID:27388681] Kobayashi K, et al. Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling. Plant Physiol., 2017. 173(4): p. 2340-2355 [PMID:28193764] Zhang TQ, et al. A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration. Plant Cell, 2017. 29(5): p. 1073-1087 [PMID:28389585] Kushwah S,Laxmi A The interaction between glucose and cytokinin signaling in controlling Arabidopsis thaliana seedling root growth and development. Plant Signal Behav, 2017. 12(5): p. e1312241 [PMID:28467152] Meng WJ, et al. Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL. Plant Cell, 2017. 29(6): p. 1357-1372 [PMID:28576846] Kobayashi K,Iwase A Simultaneous but spatially different regulation of non-photosynthetic callus formation and photosynthetic root development after shoot removal. Plant Signal Behav, 2017. 12(6): p. e1338999 [PMID:28594268] Liu B,De Storme N,Geelen D Cold interferes with male meiotic cytokinesis in Arabidopsis thaliana independently of the AHK2/3-AHP2/3/5 cytokinin signaling module. Cell Biol. Int., 2017. 41(8): p. 879-889 [PMID:28618065] Zhang F,May A,Irish VF Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL. Trends Plant Sci., 2017. 22(10): p. 815-817 [PMID:28886911] Yan Z, et al. Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1. Plant Physiol., 2017. 175(3): p. 1438-1454 [PMID:28931628] Rong XF, et al. Type-B ARRs Control Carpel Regeneration Through Mediating AGAMOUS Expression in Arabidopsis. Plant Cell Physiol., 2018. 59(4): p. 756-764 [PMID:29186581] Bustillo-Avendaño E, et al. Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis. Plant Physiol., 2018. 176(2): p. 1709-1727 [PMID:29233938] Waldie T,Leyser O Cytokinin Targets Auxin Transport to Promote Shoot Branching. Plant Physiol., 2018. 177(2): p. 803-818 [PMID:29717021]