PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID GSVIVT01028862001
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; rosids incertae sedis; Vitales; Vitaceae; Vitis
Family C2H2
Protein Properties Length: 120aa    MW: 13606.7 Da    PI: 10.1376
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
GSVIVT01028862001genomeGenoscopeView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.80.000373049118
                       EEET..TTTEEESSHHHHHH CS
            zf-C2H2  1 ykCp..dCgksFsrksnLkr 18
                       ++Cp  dC+ s++rk +L+r
  GSVIVT01028862001 30 FTCPvgDCHSSYRRKVHLTR 49
                       89****************86 PP

2zf-C2H214.30.000125984123
                       EEET..TTTEEESSHHHHHHHHHH.T CS
            zf-C2H2  1 ykCp..dCgksFsrksnLkrHirt.H 23
                       ++Cp  +C+ +F  +s+ krH +  H
  GSVIVT01028862001 59 FTCPvqNCNSRFAFQSSIKRHVKEfH 84
                       89********************9988 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.609.0E-52756IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM00355283054IPR015880Zinc finger, C2H2-like
SuperFamilySSF576671.3E-55785No hitNo description
Gene3DG3DSA:3.30.160.602.1E-55786IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.7835989IPR007087Zinc finger, C2H2
SMARTSM003550.175984IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002806184IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 120 aa     Download sequence    Send to blast
MLNGLVSGGE LPEKLHQVAS SHTTCFERPF TCPVGDCHSS YRRKVHLTRL LLKHQGKLFT  60
CPVQNCNSRF AFQSSIKRHV KEFHDESPPN NVGSKQQTIR MLRNWVWKGV QICFKVADA*
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Both isoforms 1 and 2 transcripts are expressed in seedlings and both TFIIIA and TFIIIA-C are present at similar ratios in 10-day-old seedlings (at protein level). In correlation with the reorganization of 5S rDNA chromatin to a mature state, full-length isoform 1 protein TFIIIA with transcriptional activity accumulates and permits de novo transcription of 5S rRNA. Isoforms 1 and 2 transcripts accumulate in various tissues of the reproductive phase, including flowers and siliques, but only isoform 2 is present in mature seeds. In flowers, both TFIIIA and TFIIIA-C are present at similar ratios (at protein level). Very low amounts of TFIIIA are found in extracts from fresh siliques compared to TFIIIA-C. The amount of full-length TFIIIA protein progressively increases from fresh siliques to seeds concomitant with lower proportions of the shorter TFIIIA-C protein (at protein level) thus leading to 5S rRNA accumulation in the seed. {ECO:0000269|PubMed:22353599}.
UniprotTISSUE SPECIFICITY: Expressed in seedlings, flowers, siliques and seeds. {ECO:0000269|PubMed:22353599}.
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (PubMed:22353599). Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599). Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599). {ECO:0000269|PubMed:12711688, ECO:0000269|PubMed:22353599}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAM4521311e-148AM452131.2 Vitis vinifera contig VV78X126810.14, whole genome shotgun sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002278827.12e-33PREDICTED: transcription factor IIIA
SwissprotQ84MZ42e-19TF3A_ARATH; Transcription factor IIIA
TrEMBLF6H6C75e-74F6H6C7_VITVI; Uncharacterized protein
STRINGVIT_16s0050g01100.t018e-75(Vitis vinifera)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP29811627
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G72050.28e-22transcription factor IIIA