PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; rosids incertae sedis; Vitales; Vitaceae; Vitis

Family

C2H2

Protein Properties

Length: 388aa MW: 43061.8 Da PI: 8.5963

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
GSVIVT01011587001	genome	Genoscope	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	18.8	4.4e-06	58	80	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 y+C++C++ F r nL+ H r+H GSVIVT01011587001 58 YVCEICNQGFQRDQNLQMHRRRH 80 9*********************9 PP
2	zf-C2H2	16.3	2.8e-05	135	157	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k + +s++k H++t+ GSVIVT01011587001 135 WVCEKCSKGYAVQSDYKAHLKTC 157 58*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	1.5E-5	57	80	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	1.89E-5	57	80	No hit	No description
PROSITE profile	PS50157	10.97	58	80	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0052	58	80	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	60	80	IPR007087	Zinc finger, C2H2
SMART	SM00355	130	99	129	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	3.9E-4	126	156	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	1.89E-5	130	155	No hit	No description
SMART	SM00355	60	135	162	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009630	Biological Process	gravitropism
GO:0009965	Biological Process	leaf morphogenesis
GO:0010601	Biological Process	positive regulation of auxin biosynthetic process
GO:0048444	Biological Process	floral organ morphogenesis
GO:2000012	Biological Process	regulation of auxin polar transport
GO:2000904	Biological Process	regulation of starch metabolic process
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043621	Molecular Function	protein self-association
GO:0044212	Molecular Function	transcription regulatory region DNA binding
GO:0046872	Molecular Function	metal ion binding
GO:0046982	Molecular Function	protein heterodimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 388 aa Download sequence Send to blast
MLENTAAAST APSSSSDAFT SLENGVCNKR KRRPAGTPDP DAEVVSLSPK TLLESDRYVC 60 EICNQGFQRD QNLQMHRRRH KVPWKLLKRE TQEVKKRVFV CPEPSCLHHD PLHALGDLVG 120 IKKHFRRKHS NHKQWVCEKC SKGYAVQSDY KAHLKTCGTR GHSCDCGRVF SRVESFIEHQ 180 DACAVRQVRP ELQTLQPACS SRTASSTSPS SDNNFSRVQL PGLTLPKPAE TVFLCLERNN 240 PSPSDLQHNL ELRLLPSPNT SSPREMNTAE PALAASRLKE LASEQLKLAM AEKASAEEAR 300 REAKRQIELA ELEFANARRI RQQAQAELEK AQILKEQAIK KVSSTILQIT CHACKHQFQA 360 TAAGAPSDET SLAMSYMSSA LTEGEGE*

Sequence ? help Back to Top

Protein Sequence Length: 388 aa Download sequence Send to blast

MLENTAAAST APSSSSDAFT SLENGVCNKR KRRPAGTPDP DAEVVSLSPK TLLESDRYVC  60
EICNQGFQRD QNLQMHRRRH KVPWKLLKRE TQEVKKRVFV CPEPSCLHHD PLHALGDLVG  120
IKKHFRRKHS NHKQWVCEKC SKGYAVQSDY KAHLKTCGTR GHSCDCGRVF SRVESFIEHQ  180
DACAVRQVRP ELQTLQPACS SRTASSTSPS SDNNFSRVQL PGLTLPKPAE TVFLCLERNN  240
PSPSDLQHNL ELRLLPSPNT SSPREMNTAE PALAASRLKE LASEQLKLAM AEKASAEEAR  300
REAKRQIELA ELEFANARRI RQQAQAELEK AQILKEQAIK KVSSTILQIT CHACKHQFQA  360
TAAGAPSDET SLAMSYMSSA LTEGEGE*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	4e-18	133	183	5	55	Zinc finger protein JACKDAW
5b3h_F	4e-18	133	183	5	55	Zinc finger protein JACKDAW
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in cotyledons and the vasculature of reosette leaves. Weak expression in hypocotyls and floral organs, but not detected in roots and inflorescence stems. {ECO:0000269\|PubMed:24039602}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor regulating starch metabolism by binding directly to the promoter of QQS (PubMed:21556057). The IDD14beta isoform attenuates the transcription factor activity by competitively forming heterodimers with reduced DNA-binding capacity(PubMed:21556057). Regulates lateral organ morphogenesis and gravitropic responses (PubMed:24039602). Has a redundant role with IDD16 in directing leaf and floral organ morphogenesis (PubMed:24039602). Involved in the establishment of auxin gradients through the regulation of auxin biosynthesis and transport (PubMed:24039602). {ECO:0000269\|PubMed:21556057, ECO:0000269\|PubMed:24039602}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not regulated by auxin. {ECO:0000269\|PubMed:24039602}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AM423719	0.0	AM423719.2 Vitis vinifera contig VV78X143442.4, whole genome shotgun sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002285189.1	0.0	PREDICTED: protein SHOOT GRAVITROPISM 5
Swissprot	Q9C9X7	1e-151	IDD14_ARATH; Protein indeterminate-domain 14
TrEMBL	A0A438DGK4	0.0	A0A438DGK4_VITVI; Protein SHOOT GRAVITROPISM 5
TrEMBL	A5ADE6	0.0	A5ADE6_VITVI; Uncharacterized protein
STRING	VIT_01s0011g06400.t01	0.0	(Vitis vinifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Representative plant	OGRP95	16	242

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G68130.1	1e-136	indeterminate(ID)-domain 14

Link Out ? help Back to Top
Phytozome	GSVIVT01011587001
Entrez Gene	100262958

Publications ? help Back to Top
Velasco R, et al. A high quality draft consensus sequence of the genome of a heterozygous grapevine variety. PLoS ONE, 2007. 2(12): p. e1326 [PMID:18094749] Arendsee ZW,Li L,Wurtele ES Coming of age: orphan genes in plants. Trends Plant Sci., 2014. 19(11): p. 698-708 [PMID:25151064] Qu Y, et al. Peroxisomal CuAOζ and its product H2O2 regulate the distribution of auxin and IBA-dependent lateral root development in Arabidopsis. J. Exp. Bot., 2017. 68(17): p. 4851-4867 [PMID:28992128]