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PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Home TFext BLAST Prediction Download Help About Links PlantRegMap |
Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | GSBRNA2T00141838001 | ||||||||
Common Name | GSBRNA2T00141838001 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
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Family | E2F/DP | ||||||||
Protein Properties | Length: 465aa MW: 50710.4 Da PI: 4.6582 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 76.5 | 2.5e-24 | 147 | 212 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+k ++l++++e+g+++ln++a+ L +v ++RRiYDi+NVLe+++liek kn+i wkg GSBRNA2T00141838001 147 RYDSSLGLLTKKCVNLIKQAEDGMLDLNKAAEVL---EV--QKRRIYDITNVLEGIDLIEKPFKNRILWKG 212 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 4.1E-26 | 143 | 214 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 2.45E-15 | 147 | 210 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.1E-29 | 147 | 212 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 3.0E-21 | 149 | 212 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF144074 | 1.73E-32 | 225 | 329 | No hit | No description |
CDD | cd14660 | 3.56E-48 | 225 | 329 | No hit | No description |
Pfam | PF16421 | 5.0E-33 | 228 | 327 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 465 aa Download sequence Send to blast |
MSGGVRPSPG HSQPPPSSSN PVVPPIRRHL AFASTKPPFH PSDYRRFTPS YDSSSLCGIV 60 DREEDAVVLR SPSRKRKSMM DVVTTNSNGF TSSGSTSIHN SPCHTPVSAK GGRVNTKSRA 120 KGTQSVPQTP ISNAGSPATL TPSGSCRYDS SLGLLTKKCV NLIKQAEDGM LDLNKAAEVL 180 EVQKRRIYDI TNVLEGIDLI EKPFKNRILW KGVDASRPGD VDADVAVLQA EIENLNLEEQ 240 ALDSQIRETE ERLRDLSENE KNQKWLFVTE EDIKSLPGFQ NQTLIAVKAP HGTTLEVPDP 300 DEAGDVPQRR YRIILRSTMG PIDVYLVSEF ENTNGSVAPP ACLPPIASCS GSTENHDIEA 360 LTRDNTETAI EHQMSQDHAH AQPGDTSDLN YLQEQVGGML KITPSDIEND DTDYWLLSNA 420 EISMTDIWNT DSGIDWDYGI ADVSTPPPVM GEEIAPSAID SKPR* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 5e-21 | 142 | 213 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Nucleic Localization Signal ? help Back to Top | |||
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No. | Start | End | Sequence |
1 | 72 | 77 | SRKRKS |
Expression -- Description ? help Back to Top | ||||||
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Source | Description | |||||
Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}. | |||||
Uniprot | TISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}. |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | GSBRNA2T00141838001 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_013734331.1 | 0.0 | transcription factor E2FA-like isoform X1 | ||||
Swissprot | Q9FNY0 | 0.0 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | A0A398A3I8 | 0.0 | A0A398A3I8_BRACM; Uncharacterized protein | ||||
STRING | Bra023047.1-P | 0.0 | (Brassica rapa) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM808 | 28 | 121 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.1 | 0.0 | E2F transcription factor 3 |
Publications ? help Back to Top | |||
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