![]() |
PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
|
Home TFext BLAST Prediction Download Help About Links PlantRegMap |
Transcription Factor Information
Basic Information? help Back to Top | |||||||||
---|---|---|---|---|---|---|---|---|---|
TF ID | GSBRNA2T00141197001 | ||||||||
Common Name | GSBRNA2T00141197001, LOC106445598 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
|
||||||||
Family | E2F/DP | ||||||||
Protein Properties | Length: 483aa MW: 52511.6 Da PI: 4.7007 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
|
Signature Domain? help Back to Top | |||||||
---|---|---|---|---|---|---|---|
No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 82.2 | 4.3e-26 | 160 | 225 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++++g+++ln++a++L +v ++RRiYDi+NVLe+++liek kn+i wkg GSBRNA2T00141197001 160 RYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETL---EV--QKRRIYDITNVLEGIDLIEKPLKNRILWKG 225 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 6.4E-28 | 156 | 227 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 2.9E-32 | 160 | 225 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.9E-16 | 160 | 223 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 7.6E-23 | 162 | 225 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 1.46E-48 | 238 | 342 | No hit | No description |
SuperFamily | SSF144074 | 8.89E-33 | 238 | 342 | No hit | No description |
Pfam | PF16421 | 6.1E-33 | 242 | 340 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
---|---|---|---|---|---|---|
GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
---|
Protein Sequence Length: 483 aa Download sequence Send to blast |
MSGGVRSSPG SSRQPPPPPQ HPAASVPVVP PIRRHLAFAS TKPPFHPSDN YHRFTPSHLA 60 NNLVNGCGGL VDREEDAVVL RSPSRKRKST MDVVTTTTTS TSNGFTSSDG FTSSPCRTPV 120 SAKGDRVNIK SKAKGNQSIP QTPISNIGSP ATLTPSGSCR YDSSLGLLTK KFVNLIKQAK 180 DGMLDLNKAA ETLEVQKRRI YDITNVLEGI DLIEKPLKNR ILWKGVDALR PGDVDADVSD 240 VQAEIENLSL EEQALDNQIR ETEQRLRDLS ENEKNQKWLF VTEEDIKSLP GFQNQTLIAV 300 KAPHGTTLEV PDPDEAVGHP QRRYRIILRS TMGPIDVYLV SEFEEKFEDT NGPAAPPPPP 360 PCLPIASCSG STENHNIEAL TVDNTGTAVE DQLSQTHANA QPGETSDLNY LEEQVGGMLK 420 ITPSEVENDD TDYWLLSNAD ISMTDIWKTD SGIDWDYGIA DVSTPPPIIG DISPTAIDSI 480 PR* |
3D Structure ? help Back to Top | ||||||
---|---|---|---|---|---|---|
PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 4e-23 | 155 | 226 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Nucleic Localization Signal ? help Back to Top | |||
---|---|---|---|
No. | Start | End | Sequence |
1 | 83 | 88 | SRKRKS |
Expression -- Description ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Source | Description | |||||
Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}. | |||||
Uniprot | TISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}. |
Functional Description ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Cis-element ? help Back to Top | |
---|---|
Source | Link |
PlantRegMap | GSBRNA2T00141197001 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Source | Hit ID | E-value | Description | |||
GenBank | JN942984 | 0.0 | JN942984.1 Brassica juncea E2F transcription factor (E2Fa) mRNA, partial cds. |
Annotation -- Protein ? help Back to Top | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-value | Description | ||||
Refseq | XP_013742633.1 | 0.0 | transcription factor E2FA isoform X1 | ||||
Swissprot | Q9FNY0 | 0.0 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | A0A0D3BRP2 | 0.0 | A0A0D3BRP2_BRAOL; Uncharacterized protein | ||||
TrEMBL | A0A3P6C945 | 0.0 | A0A3P6C945_BRAOL; Uncharacterized protein (Fragment) | ||||
STRING | Bo4g035150.1 | 0.0 | (Brassica oleracea) |
Orthologous Group ? help Back to Top | |||
---|---|---|---|
Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM808 | 28 | 121 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Hit ID | E-value | Description | ||||
AT2G36010.1 | 0.0 | E2F transcription factor 3 |
Link Out ? help Back to Top | |
---|---|
Entrez Gene | 106445598 |
Publications ? help Back to Top | |||
---|---|---|---|
|