PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica

Family

MYB

Protein Properties

Length: 322aa MW: 36622.9 Da PI: 8.3119

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
GSBRNA2T00007508001	genome	Genoscope	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	37	7.7e-12	12	48	11	48
HHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 11 llvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +l+++v+qlG + W+ I++++ gR +kqc++rw+++l GSBRNA2T00007508001 12 KLIRLVRQLGERKWAMISEKLE-GRAGKQCRERWHNHL 48 89******************.***********97 PP
2	Myb_DNA-binding	53.8	4.3e-17	55	96	2	45
SSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHH CS Myb_DNA-binding 2 grWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwq 45 + W++eE+ lv+a+k+ G++ W+ Ia+ ++ gRt++++k++w+ GSBRNA2T00007508001 55 DGWSEEEERVLVEAHKRIGNK-WAEIAKLIP-GRTENSIKNHWN 96 56*****************.*****.*********8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	13.574	1	48	IPR017930	Myb domain
SMART	SM00717	1.5E-4	5	50	IPR001005	SANT/Myb domain
CDD	cd00167	4.17E-9	11	48	No hit	No description
Gene3D	G3DSA:1.10.10.60	5.9E-21	11	56	IPR009057	Homeodomain-like
Pfam	PF00249	1.5E-9	12	48	IPR001005	SANT/Myb domain
SuperFamily	SSF46689	1.76E-26	27	108	IPR009057	Homeodomain-like
PROSITE profile	PS51294	23.764	49	103	IPR017930	Myb domain
SMART	SM00717	6.4E-15	53	101	IPR001005	SANT/Myb domain
Pfam	PF00249	3.5E-15	56	96	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	2.8E-20	57	101	IPR009057	Homeodomain-like
CDD	cd00167	1.22E-11	57	99	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 322 aa Download sequence Send to blast
EFVNIRTYMC RKLIRLVRQL GERKWAMISE KLEGRAGKQC RERWHNHLRP DIKKDGWSEE 60 EERVLVEAHK RIGNKWAEIA KLIPGRTENS IKNHWNATKR RQNSKRKQKR RQENADNYDS 120 DLPPAAKRPC ILQDYIKSVY NNVENKASDD NKNENSISVL STPNLDQTYS DGDSTSSVLG 180 DPYDEELVYL QNIFANHPVS LDNIGLNQTS DEVNMIKNPR SHKSVWTHHQ DQAMVAVPEN 240 KPHLASDIYL SYLLNGTASS SYSNPHFPSS SSSTSSTTVE KGGYSEFLVP HANSTGEKRE 300 MDLMEMLSGS IQGGNKCFPL F*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1mse_C	3e-39	12	102	14	104	C-Myb DNA-Binding Domain
1msf_C	3e-39	12	102	14	104	C-Myb DNA-Binding Domain
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	98	109	KRRQNSKRKQKR
2	104	111	KRKQKRRQ

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: During female gametogenesis, expressed in the female gametophyte at stage FG4 (four-nucleate stage) in all four nuclei. Expressed in the central cell in unfused polar nuclei at stage FG5 and secondary nucleus at stage FG6. Not expressed in mature female gametophytes (stage FG7). {ECO:0000269\|PubMed:24068955}.
Uniprot	TISSUE SPECIFICITY: Expressed in ovary septum and stamen filament. {ECO:0000269\|PubMed:24068955}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor required for female gametophyte fertility. Acts redundantly with MYB64 to initiate the FG5 transition during female gametophyte development. The FG5 transition represents the switch between free nuclear divisions and cellularization-differentiation in female gametophyte, and occurs during developmental stage FG5. {ECO:0000269\|PubMed:24068955}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	GSBRNA2T00007508001

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013620052.1	0.0	PREDICTED: transcription factor MYB48
Swissprot	Q9FIM4	1e-169	MY119_ARATH; Transcription factor MYB119
TrEMBL	A0A078JTA9	0.0	A0A078JTA9_BRANA; BnaCnng69750D protein (Fragment)
STRING	Bo2g028290.1	0.0	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4265	26	56

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G58850.1	1e-152	myb domain protein 119

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Chalhoub B, et al. Plant genetics. Early allopolyploid evolution in the post-Neolithic Brassica napus oilseed genome. Science, 2014. 345(6199): p. 950-3 [PMID:25146293]