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Plant Transcription
Factor Database
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Transcription Factor Information
Basic
Information? help
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TF ID |
GRMZM2G052515_P01 |
Common Name | cl815_1(203), ZEAMMB73_474017 |
Organism |
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Taxonomic ID |
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Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea
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Family |
E2F/DP |
Protein Properties |
Length: 446aa MW: 48686.4 Da PI: 4.4527 |
Description |
E2F/DP family protein |
Gene Model |
Gene Model ID |
Type |
Source |
Coding Sequence |
GRMZM2G052515_P01 | genome | MaizeSequence | View CDS |
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Signature Domain? help Back to Top |
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No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
1 | E2F_TDP | 83.3 | 2e-26 | 130 | 195 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
r+++sL+llt+kfl+ll+ ++ giv+ln++a++L +v ++RRiYDi+NVLe+++liekk kn+irwkg
GRMZM2G052515_P01 130 RYDSSLGLLTKKFLNLLKGAPGGIVDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNNIRWKG 195
6899******************************...99..****************************98 PP
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Gene Ontology ? help Back to Top |
GO Term |
GO Category |
GO Description |
GO:0006355 | Biological Process | regulation of transcription, DNA-templated |
GO:0005634 | Cellular Component | nucleus |
GO:0005667 | Cellular Component | transcription factor complex |
GO:0003677 | Molecular Function | DNA binding |
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
Protein Sequence Length: 446 aa
Download sequence Send
to blast |
MAAAAGDGAG EARARALLQQ HRPFATPPGE YHHFGAPSAA ADEMVEAVVL RTPLKRKHND 60 RTENEAAESN DWMSPGYANA GSSPVPTPPS GKGLKASTKP KATKGQKSGP QTPLGFGSPG 120 NPSTPVGGCR YDSSLGLLTK KFLNLLKGAP GGIVDLNNAA ETLEVQKRRI YDITNVLEGI 180 GLIEKKLKNN IRWKGVDDSR PGEVSDDMSI LQADIDALTL QERNLDERIS EMRDRLRGLT 240 EDENNQKWLY VTEEDIKSLP CFQNQTLIAI KAPHGTTLEV PDPDEVNDYP QRRYRIVLRS 300 TMGPIDVYLV SQFEEMSGME TPPRPTQTIS MDSLENPRTP LAADCNKVTG MESNIHGGLI 360 LPSDAPSSSQ DISGMMKIVP SELDADTDYW LLSDNTGVSM TNMWETGPDE WDGIEKFNAE 420 DFLEVGTPQQ QDKPADVVDD DPSCII
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Expression --
Description ? help
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Source |
Description |
Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant at the G1/S transition. Lower but constant level in the following phases. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:16514015}. |
Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}. |
Uniprot | TISSUE SPECIFICITY: Expressed in proliferating cells and several differentiated tissues. Detected in inflorescence and shoot apical meristems, cotyledonary vascular tissues, leaf primordia, young leaves, base of trichomes, central cylinder and elongation zone of roots, lateral root primordia, flowers, pistils of immature flowers and pollen grains. {ECO:0000269|PubMed:16514015}. |
Uniprot | TISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}. |
Functional Description ? help
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Source |
Description |
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}. |
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Regulation -- Description ? help
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Source |
Description |
UniProt | INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}. |
Annotation --
Nucleotide ? help
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Source |
Hit ID |
E-value |
Description |
GenBank | BT034349 | 0.0 | BT034349.1 Zea mays full-length cDNA clone ZM_BFc0009D23 mRNA, complete cds. |
GenBank | BT064435 | 0.0 | BT064435.1 Zea mays full-length cDNA clone ZM_BFc0168K16 mRNA, complete cds. |
GenBank | EU973980 | 0.0 | EU973980.1 Zea mays clone 425487 transcription factor E2F2 mRNA, complete cds. |
Publications
? help Back to Top |
- Alexandrov NN, et al.
Insights into corn genes derived from large-scale cDNA sequencing. Plant Mol. Biol., 2009. 69(1-2): p. 179-94 [PMID:18937034] - Magyar Z, et al.
Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083] - Heyndrickx KS,Vandepoele K
Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] - Wu M,Liu L,Hijazi H,Chan C
A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] - Kobayashi K, et al.
Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]
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