PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID FANhyb_rscf00000005.1.g00021.1
Organism
Fragaria x ananassa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Rosoideae; Potentilleae; Fragariinae; Fragaria
Family MYB_related
Protein Properties Length: 573aa    MW: 64296.6 Da    PI: 8.3009
Description MYB_related family protein
Gene Model
Gene Model ID Type Source Coding Sequence
FANhyb_rscf00000005.1.g00021.1genomekazusaView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding30.21e-09343378137
                                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-H CS
                 Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtl 37 
                                     +g W++eEd++l +++ ++G g+W++++   g g+ l
  FANhyb_rscf00000005.1.g00021.1 343 KGLWSPEEDQRLRNYIIKHGHGCWSSVPINAG-GLRL 378
                                     678***************************99.5543 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF027372.0E-173195IPR0061763-hydroxyacyl-CoA dehydrogenase, NAD binding
SuperFamilySSF517353.62E-123196IPR016040NAD(P)-binding domain
Gene3DG3DSA:3.40.50.7202.0E-183198IPR016040NAD(P)-binding domain
PROSITE patternPS00067095119IPR0061803-hydroxyacyl-CoA dehydrogenase, conserved site
PfamPF007255.9E-2198191IPR0061083-hydroxyacyl-CoA dehydrogenase, C-terminal
SuperFamilySSF481792.47E-2598208IPR0089276-phosphogluconate dehydrogenase C-terminal domain-like
Gene3DG3DSA:1.10.1040.109.4E-2099192IPR0133286-phosphogluconate dehydrogenase, domain 2
SuperFamilySSF481791.7E-22226314IPR0089276-phosphogluconate dehydrogenase C-terminal domain-like
PfamPF007254.6E-5230319IPR0061083-hydroxyacyl-CoA dehydrogenase, C-terminal
Gene3DG3DSA:1.10.1040.105.1E-18236315IPR0133286-phosphogluconate dehydrogenase, domain 2
SuperFamilySSF466897.8E-8338404IPR009057Homeodomain-like
PROSITE profilePS5129415.309338402IPR017930Myb domain
Gene3DG3DSA:1.10.10.601.1E-12338406IPR009057Homeodomain-like
SMARTSM007172.9E-4342400IPR001005SANT/Myb domain
PfamPF002491.2E-7343380IPR001005SANT/Myb domain
CDDcd001671.28E-5346398No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006631Biological Processfatty acid metabolic process
GO:0055114Biological Processoxidation-reduction process
GO:0003677Molecular FunctionDNA binding
GO:0003857Molecular Function3-hydroxyacyl-CoA dehydrogenase activity
Sequence ? help Back to Top
Protein Sequence    Length: 573 aa     Download sequence    Send to blast
MRTSHSLRAI LPRKIPILYA CLSKTRIDGE SVIDLNLIGE KTKSHDRIIG AHFFSPAHIM  60
PLLEIVRTNR TSPQVIVDLL EVGKKIKKTP VVVGNCTGFA VNRMFFPYTQ AGLLLIERGA  120
DVYQIDRAIT KFGMPMGPFR LADLVGFGVA IATGLQFIEN FPERTYKSML IPMMQEDGRA  180
GETTKRGFYV YDDKRKAKPD PELKKYIEKS RSISGLSVDA KLAKLPEKDI VEMIFFPVVN  240
EACRVYAEGI AVKAADLDIA SVMGMGFPPY RGGIMFWADL VGSKYIYSRL EQWSNTYGEF  300
FKPCAYLAER AAQGAPLRKV EACVVRMGCK SSDSPKPKPK HRKGLWSPEE DQRLRNYIIK  360
HGHGCWSSVP INAGGLRLHN ICLEGQTMRL KNFWHSYLKK KVAKADEDQD QMELAQSKSQ  420
YTSTSSSDHN LDQHSPCSEK LTSIQIPSYN ESPTLAPQID HQSQRPSPLP RVLFAEWLSL  480
DHVQGGSIGN NIGIDQHNYN PRADHGLGQS YTYNNEATFG TSGFHHGPST QDIMNSEFRY  540
DPQDLIPGTG FVDFISEGDL VTDFTLHNDV MYM
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2wtb_A1e-17231317428714FATTY ACID MULTIFUNCTIONAL PROTEIN (ATMFP2)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in peroxisomal fatty acid beta-oxidation during seed germination. Possesses enoyl-CoA hydratase activity against long chain substrates (C14-C18) and 3-hydroxyacyl-CoA dehydrogenase activity against chains of variable sizes (C6-C18) (PubMed:10521521, PubMed:16507084, PubMed:20463021). Possesses 3-hydroxy-3-phenylpropionyl-CoA dehydrogenase activity and is involved in the peroxisomal beta-oxidation pathway for the biosynthesis of benzoic acid (BA). Required for the accumulation in seeds of substituted hydroxybenzoylated choline esters, which are BA-containing secondary metabolites (PubMed:24254312). {ECO:0000269|PubMed:10521521, ECO:0000269|PubMed:16507084, ECO:0000269|PubMed:20463021, ECO:0000269|PubMed:24254312}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004296857.10.0PREDICTED: peroxisomal fatty acid beta-oxidation multifunctional protein MFP2
SwissprotQ9ZPI51e-172MFP2_ARATH; Peroxisomal fatty acid beta-oxidation multifunctional protein MFP2
TrEMBLA0A2P6QYH30.0A0A2P6QYH3_ROSCH; Putative 3-hydroxyacyl-CoA dehydrogenase, Hydro-lyase, Isomerase
STRINGXP_004296857.10.0(Fragaria vesca)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G25560.11e-15myb domain protein 18
Publications ? help Back to Top
  1. Richmond TA,Bleecker AB
    A defect in beta-oxidation causes abnormal inflorescence development in Arabidopsis.
    Plant Cell, 1999. 11(10): p. 1911-24
    [PMID:10521521]
  2. Eastmond PJ,Graham IA
    The multifunctional protein AtMFP2 is co-ordinately expressed with other genes of fatty acid beta-oxidation during seed germination in Arabidopsis thaliana (L.) Heynh.
    Biochem. Soc. Trans., 2000. 28(2): p. 95-9
    [PMID:10816107]
  3. Bongcam V, et al.
    Importance of sequences adjacent to the terminal tripeptide in the import of a peroxisomal Candida tropicalis protein in plant peroxisomes.
    Planta, 2000. 211(1): p. 150-7
    [PMID:10923716]
  4. Bayer EM, et al.
    Arabidopsis cell wall proteome defined using multidimensional protein identification technology.
    Proteomics, 2006. 6(1): p. 301-11
    [PMID:16287169]
  5. Rylott EL, et al.
    The Arabidopsis thaliana multifunctional protein gene (MFP2) of peroxisomal beta-oxidation is essential for seedling establishment.
    Plant J., 2006. 45(6): p. 930-41
    [PMID:16507084]
  6. Reumann S, et al.
    Proteome analysis of Arabidopsis leaf peroxisomes reveals novel targeting peptides, metabolic pathways, and defense mechanisms.
    Plant Cell, 2007. 19(10): p. 3170-93
    [PMID:17951448]
  7. Zheng BS, et al.
    Arabidopsis sterol carrier protein-2 is required for normal development of seeds and seedlings.
    J. Exp. Bot., 2008. 59(12): p. 3485-99
    [PMID:18687588]
  8. Wiszniewski AA,Zhou W,Smith SM,Bussell JD
    Identification of two Arabidopsis genes encoding a peroxisomal oxidoreductase-like protein and an acyl-CoA synthetase-like protein that are required for responses to pro-auxins.
    Plant Mol. Biol., 2009. 69(5): p. 503-15
    [PMID:19043666]
  9. Arent S,Christensen CE,Pye VE,Nørgaard A,Henriksen A
    The multifunctional protein in peroxisomal beta-oxidation: structure and substrate specificity of the Arabidopsis thaliana protein MFP2.
    J. Biol. Chem., 2010. 285(31): p. 24066-77
    [PMID:20463021]
  10. Bussell JD,Reichelt M,Wiszniewski AA,Gershenzon J,Smith SM
    Peroxisomal ATP-binding cassette transporter COMATOSE and the multifunctional protein abnormal INFLORESCENCE MERISTEM are required for the production of benzoylated metabolites in Arabidopsis seeds.
    Plant Physiol., 2014. 164(1): p. 48-54
    [PMID:24254312]