PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus

Family

GRAS

Protein Properties

Length: 568aa MW: 61414.5 Da PI: 6.5903

Description

GRAS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Eucgr.C04156.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	GRAS	425.3	5.1e-130	183	545	1	374
GRAS 1 lvelLlecAeavssgdlelaqalLarlsel..aspdgdpmqRlaayfteALaarlarsvselykalppsetseknsseelaalklfsevsPil 91 lv++L++cAe v+ gd++la +l+++++ l + + + + ++a yf AL +rl++ l + ++s e+ ++ f+e++P+l Eucgr.C04156.1.p 183 LVHALMTCAESVQRGDASLAGSLVEEMRALltRVDTSRGIGKVAGYFIDALGRRLLG--------LGSAPAS---AFENEVLYHHFYEACPYL 264 689*************************5334444799*************........3333333...3445567889**** PP GRAS 92 kfshltaNqaIleavegeervHiiDfdisqGlQWpaLlqaLasRpegppslRiTgvgspesgskeeleetgerLakfAeelgvpfefnvlvak 184 kf+h+taNqaIlea++g+++vH+iDf++++GlQWpaL+qaLa Rp+gpp lR+Tg+g+p+++ ++ l+e+g rLa++A++++v+f f+ ++a+ Eucgr.C04156.1.p 265 KFAHFTANQAILEAFDGHDCVHVIDFNLMHGLQWPALIQALALRPRGPPLLRLTGIGPPSPDGRDVLREIGLRLAELARSVNVRFAFRGVAAS 357 ***************************************************************************************** PP GRAS 185 rledleleeLrvkpgEalaVnlvlqlhrlldesvsleserdevLklvkslsPkvvvvveqeadhnsesFlerflealeyysalfdsleaklpr 277 rled+++++L+v+p+Ea+aVn+++qlhrll ++ + + ++ +vL ++sl+Pk+++v+eqea+hn++ Fl+rf+eal+yys+lfdslea p Eucgr.C04156.1.p 358 RLEDVKPWMLQVSPKEAVAVNSIMQLHRLLGSDPPRDPPIGSVLPWIRSLNPKIMTVAEQEANHNRPGFLDRFTEALYYYSTLFDSLEAACP- 449 **************************************************************************************75. PP GRAS 278 eseerikvErellgreivnvvacegaerrerhetlekWrerleeaGFkpvplsekaakqaklllrkvksdgyrveeesgslvlgWkdrpLvsv 370 + ++ + +++l+rei+n+v cega+r+erhe l +Wr+rl++aGF+p++l+++a kqa++ll ++ +gy+vee++g+l+l+W++rpL+++ Eucgr.C04156.1.p 450 -VQPDKALAEMYLQREICNIVGCEGAARVERHEPLDRWRARLGRAGFRPLHLGSNAFKQASMLLTLFSTEGYSVEENEGCLTLCWHSRPLIAA 541 .45667788899***************************************************************************** PP GRAS 371 SaWr 374 SaW+ Eucgr.C04156.1.p 542 SAWQ 545 *6 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM01129	2.2E-21	48	120	No hit	No description
Pfam	PF12041	5.6E-31	48	111	IPR021914	Transcriptional factor DELLA, N-terminal
PROSITE profile	PS50985	64.266	157	525	IPR005202	Transcription factor GRAS
Pfam	PF03514	1.8E-127	183	545	IPR005202	Transcription factor GRAS

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated

Sequence ? help Back to Top
Protein Sequence Length: 568 aa Download sequence Send to blast
MGPFDPSAAA AAAAAAAASS SSSSSCSGGS APKRHHHHHH HHPPPDLDGL LAGAGYKVRS 60 SELHHVAQRL ERLETALVNS AAHIPHLASD AVHYNPSDLA SWVDSMLSEL PSSSFSSPCL 120 PSGFPDPYSP AAAALGGGWV DHPSCSPHPQ PHQNVVVPQQ PQPQQQQQLT VVTALEEDSG 180 IQLVHALMTC AESVQRGDAS LAGSLVEEMR ALLTRVDTSR GIGKVAGYFI DALGRRLLGL 240 GSAPASAFEN EVLYHHFYEA CPYLKFAHFT ANQAILEAFD GHDCVHVIDF NLMHGLQWPA 300 LIQALALRPR GPPLLRLTGI GPPSPDGRDV LREIGLRLAE LARSVNVRFA FRGVAASRLE 360 DVKPWMLQVS PKEAVAVNSI MQLHRLLGSD PPRDPPIGSV LPWIRSLNPK IMTVAEQEAN 420 HNRPGFLDRF TEALYYYSTL FDSLEAACPV QPDKALAEMY LQREICNIVG CEGAARVERH 480 EPLDRWRARL GRAGFRPLHL GSNAFKQASM LLTLFSTEGY SVEENEGCLT LCWHSRPLIA 540 ASAWQAAPTV VNSPAGVINH DDNNNQL*

Sequence ? help Back to Top

Protein Sequence Length: 568 aa Download sequence Send to blast

MGPFDPSAAA AAAAAAAASS SSSSSCSGGS APKRHHHHHH HHPPPDLDGL LAGAGYKVRS  60
SELHHVAQRL ERLETALVNS AAHIPHLASD AVHYNPSDLA SWVDSMLSEL PSSSFSSPCL  120
PSGFPDPYSP AAAALGGGWV DHPSCSPHPQ PHQNVVVPQQ PQPQQQQQLT VVTALEEDSG  180
IQLVHALMTC AESVQRGDAS LAGSLVEEMR ALLTRVDTSR GIGKVAGYFI DALGRRLLGL  240
GSAPASAFEN EVLYHHFYEA CPYLKFAHFT ANQAILEAFD GHDCVHVIDF NLMHGLQWPA  300
LIQALALRPR GPPLLRLTGI GPPSPDGRDV LREIGLRLAE LARSVNVRFA FRGVAASRLE  360
DVKPWMLQVS PKEAVAVNSI MQLHRLLGSD PPRDPPIGSV LPWIRSLNPK IMTVAEQEAN  420
HNRPGFLDRF TEALYYYSTL FDSLEAACPV QPDKALAEMY LQREICNIVG CEGAARVERH  480
EPLDRWRARL GRAGFRPLHL GSNAFKQASM LLTLFSTEGY SVEENEGCLT LCWHSRPLIA  540
ASAWQAAPTV VNSPAGVINH DDNNNQL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3g_A	2e-59	158	544	2	378	Protein SCARECROW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. Transcription coactivator of the zinc finger transcription factors GAF1/IDD2 and ENY/IDD1 in regulation of gibberellin homeostasis and signaling (PubMed:25035403). No effect of the BOI proteins on its stability. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Positively regulates XERICO expression. In contrast to RGA, it is less sensitive to GA. Its activity is probably regulated by other phytohormones such as auxin and ethylene. {ECO:0000269\|PubMed:11487693, ECO:0000269\|PubMed:11606551, ECO:0000269\|PubMed:11606552, ECO:0000269\|PubMed:14973286, ECO:0000269\|PubMed:15128937, ECO:0000269\|PubMed:16034591, ECO:0000269\|PubMed:17933900, ECO:0000269\|PubMed:25035403, ECO:0000269\|PubMed:9389651}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Eucgr.C04156.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010049952.1	0.0	PREDICTED: DELLA protein GAI
Swissprot	Q9LQT8	1e-161	GAI_ARATH; DELLA protein GAI
TrEMBL	A0A059CXT5	0.0	A0A059CXT5_EUCGR; Uncharacterized protein
STRING	XP_010049952.1	0.0	(Eucalyptus grandis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM16045	10	15

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G14920.1	1e-133	GRAS family protein

Link Out ? help Back to Top
Phytozome	Eucgr.C04156.1.p
Entrez Gene	104438490

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Gallego-Giraldo C, et al. Role of the gibberellin receptors GID1 during fruit-set in Arabidopsis. Plant J., 2014. 79(6): p. 1020-1032 [PMID:24961590] Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Marín-de la Rosa N, et al. Genome Wide Binding Site Analysis Reveals Transcriptional Coactivation of Cytokinin-Responsive Genes by DELLA Proteins. PLoS Genet., 2015. 11(7): p. e1005337 [PMID:26134422] Shi H,Wei Y,Wang Q,Reiter RJ,He C Melatonin mediates the stabilization of DELLA proteins to repress the floral transition in Arabidopsis. J. Pineal Res., 2016. 60(3): p. 373-9 [PMID:26887824] Lee SA, et al. Interplay between ABA and GA Modulates the Timing of Asymmetric Cell Divisions in the Arabidopsis Root Ground Tissue. Mol Plant, 2016. 9(6): p. 870-84 [PMID:26970019] Qu J,Kang SG,Hah C,Jang JC Molecular and cellular characterization of GA-Stimulated Transcripts GASA4 and GASA6 in Arabidopsis thaliana. Plant Sci., 2016. 246: p. 1-10 [PMID:26993231] Shahnejat-Bushehri S,Nobmann B,Devi Allu A,Balazadeh S JUB1 suppresses Pseudomonas syringae-induced defense responses through accumulation of DELLA proteins. Plant Signal Behav, 2016. 11(6): p. e1181245 [PMID:27159137] Shahnejat-Bushehri S,Tarkowska D,Sakuraba Y,Balazadeh S Arabidopsis NAC transcription factor JUB1 regulates GA/BR metabolism and signalling. Nat Plants, 2016. 2: p. 16013 [PMID:27249348] Wang H, et al. The DELLA-CONSTANS Transcription Factor Cascade Integrates Gibberellic Acid and Photoperiod Signaling to Regulate Flowering. Plant Physiol., 2016. 172(1): p. 479-88 [PMID:27406167] Li W,Wang H,Yu D Arabidopsis WRKY Transcription Factors WRKY12 and WRKY13 Oppositely Regulate Flowering under Short-Day Conditions. Mol Plant, 2016. 9(11): p. 1492-1503 [PMID:27592586] Liu B,De Storme N,Geelen D Gibberellin Induces Diploid Pollen Formation by Interfering with Meiotic Cytokinesis. Plant Physiol., 2017. 173(1): p. 338-353 [PMID:27621423] Matsuoka K, et al. Differential Cellular Control by Cotyledon-Derived Phytohormones Involved in Graft Reunion of Arabidopsis Hypocotyls. Plant Cell Physiol., 2016. 57(12): p. 2620-2631 [PMID:27986917] Zentella R, et al. The Arabidopsis O-fucosyltransferase SPINDLY activates nuclear growth repressor DELLA. Nat. Chem. Biol., 2017. 13(5): p. 479-485 [PMID:28244988] Zhang Y, et al. GA-DELLA pathway is involved in regulation of nitrogen deficiency-induced anthocyanin accumulation. Plant Cell Rep., 2017. 36(4): p. 557-569 [PMID:28275852] Zhang L,Chen L,Yu D Transcription Factor WRKY75 Interacts with DELLA Proteins to Affect Flowering. Plant Physiol., 2018. 176(1): p. 790-803 [PMID:29133369] Nelson SK,Ariizumi T,Steber CM Biology in the Dry Seed: Transcriptome Changes Associated with Dry Seed Dormancy and Dormancy Loss in the Arabidopsis GA-Insensitive sleepy1-2 Mutant. Front Plant Sci, 2017. 8: p. 2158 [PMID:29312402] Liu B,De Storme N,Geelen D Cold-Induced Male Meiotic Restitution in Arabidopsis thaliana Is Not Mediated by GA-DELLA Signaling. Front Plant Sci, 2018. 9: p. 91 [PMID:29459879] Zhang Y, et al. DELLA proteins negatively regulate dark-induced senescence and chlorophyll degradation in Arabidopsis through interaction with the transcription factor WRKY6. Plant Cell Rep., 2018. 37(7): p. 981-992 [PMID:29574486] Felipo-Benavent A, et al. Regulation of xylem fiber differentiation by gibberellins through DELLA-KNAT1 interaction. Development, 2019. [PMID:30389856] Wright DA, et al. Recovery of YAC-end sequences through complementation of an Escherichia coli pyrF mutation. Nucleic Acids Res., 1997. 25(13): p. 2679-80 [PMID:9185581]