PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus

Family

MYB_related

Protein Properties

Length: 516aa MW: 57499.1 Da PI: 9.8239

Description

MYB_related family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
EcC047503.10	genome	ECGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	22.5	2.7e-07	405	454	1	47
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHT...TTS-HHHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmg...kgRtlkqcksrwqky 47 r +++ E e lv+av++lG+g+W+ + + +Rt ++k++w ++ EcC047503.10 405 RRPFSVSEVEALVEAVEELGTGRWRDVKLRALenaDHRTYVDLKDKWKTL 454 678999*******************9999999***********986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd01769	0.0097	218	278	No hit	No description
PROSITE profile	PS51294	15.327	400	459	IPR017930	Myb domain
SMART	SM00717	1.9E-7	404	457	IPR001005	SANT/Myb domain
Pfam	PF00249	1.3E-5	405	454	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	8.1E-10	405	455	IPR009057	Homeodomain-like
SuperFamily	SSF46689	7.69E-15	406	487	IPR009057	Homeodomain-like
CDD	cd11660	2.24E-15	406	456	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 516 aa Download sequence Send to blast
AICKNEIRYG MSGNLAGAIP GFGPSFGLNV EKSGKGDVDL ADHLKDSVEN SSKYPAVTNI 60 GNQIQKPLCG NPRRVASFPR CRNNTNIGSR DGDENFPRFN KFSNKIKAFR HTQRIGDRRI 120 RKLLTSKYWR AAPKLKDCET SKADGEMKPF THKRRTFYKR ERYYGDCLYK RRTLLDRSSI 180 VTFDGVFSGE SNSSSPQKNM NSDRNGSIAM MHGVKFSIKS FRIPELFIDV PETATVGSLK 240 RSVVEAVSAI LGSGLHVGIL LRGKKIRDDN RTLLQTGISC KESLDNLGFT LEPNLQTVNS 300 AIASEDVPLT VPYDMPELLT SSPENYISDP GVSDVPSDPP PLTNSSNDVD TNPESISLHS 360 DVSSDKKMSD SRALVPVPAM PLEPLAIVPV NQKNKRSELS QRRIRRPFSV SEVEALVEAV 420 EELGTGRWRD VKLRALENAD HRTYVDLKDK WKTLVHTASI APQQRRGEPV PQELLDRVMA 480 AHAYWSQHQA KQQGKHQPGT LKITNEQADR MAIEGM

Sequence ? help Back to Top

Protein Sequence Length: 516 aa Download sequence Send to blast

AICKNEIRYG MSGNLAGAIP GFGPSFGLNV EKSGKGDVDL ADHLKDSVEN SSKYPAVTNI  60
GNQIQKPLCG NPRRVASFPR CRNNTNIGSR DGDENFPRFN KFSNKIKAFR HTQRIGDRRI  120
RKLLTSKYWR AAPKLKDCET SKADGEMKPF THKRRTFYKR ERYYGDCLYK RRTLLDRSSI  180
VTFDGVFSGE SNSSSPQKNM NSDRNGSIAM MHGVKFSIKS FRIPELFIDV PETATVGSLK  240
RSVVEAVSAI LGSGLHVGIL LRGKKIRDDN RTLLQTGISC KESLDNLGFT LEPNLQTVNS  300
AIASEDVPLT VPYDMPELLT SSPENYISDP GVSDVPSDPP PLTNSSNDVD TNPESISLHS  360
DVSSDKKMSD SRALVPVPAM PLEPLAIVPV NQKNKRSELS QRRIRRPFSV SEVEALVEAV  420
EELGTGRWRD VKLRALENAD HRTYVDLKDK WKTLVHTASI APQQRRGEPV PQELLDRVMA  480
AHAYWSQHQA KQQGKHQPGT LKITNEQADR MAIEGM

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2juh_A	5e-63	389	511	1	119	Telomere binding protein TBP1
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	116	122	DRRIRKL

Functional Description ? help Back to Top
Source	Description
UniProt	Binds specifically to the plant telomeric double-stranded DNA sequences 5'-TTTAGGG-3'. At least 2 repeats of telomeric sequences are required for binding. Induces DNA bending. {ECO:0000269\|PubMed:11513850, ECO:0000269\|PubMed:17272298}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salt stress. {ECO:0000269\|PubMed:12909688}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010032390.1	0.0	PREDICTED: telomere repeat-binding protein 4 isoform X1
Refseq	XP_010032391.1	0.0	PREDICTED: telomere repeat-binding protein 4 isoform X2
Swissprot	Q9FFY9	1e-149	TRP4_ARATH; Telomere repeat-binding protein 4
TrEMBL	A0A059AEG9	0.0	A0A059AEG9_EUCGR; Uncharacterized protein
STRING	XP_010032390.1	0.0	(Eucalyptus grandis)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G07540.1	1e-106	TRF-like 2

Publications ? help Back to Top
Zentgraf U,Hinderhofer K,Kolb D Specific association of a small protein with the telomeric DNA-protein complex during the onset of leaf senescence in Arabidopsis thaliana. Plant Mol. Biol., 2000. 42(3): p. 429-38 [PMID:10798613] Hwang MG,Chung IK,Kang BG,Cho MH Sequence-specific binding property of Arabidopsis thaliana telomeric DNA binding protein 1 (AtTBP1). FEBS Lett., 2001. 503(1): p. 35-40 [PMID:11513850] Hwang MG,Cho MH Arabidopsis thaliana telomeric DNA-binding protein 1 is required for telomere length homeostasis and its Myb-extension domain stabilizes plant telomeric DNA binding. Nucleic Acids Res., 2007. 35(4): p. 1333-42 [PMID:17272298] Fulcher N,Riha K Using Centromere Mediated Genome Elimination to Elucidate the Functional Redundancy of Candidate Telomere Binding Proteins in Arabidopsis thaliana. Front Genet, 2015. 6: p. 349 [PMID:26779251]