PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID EcC043273.40
Organism
Eucalyptus camaldulensis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus
Family NAC
Protein Properties Length: 377aa    MW: 42878.6 Da    PI: 5.2039
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
EcC043273.40genomeECGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM97.22.4e-30521941128
           NAM   1 lppGfrFhPtdeelvveyLkkkvegkk....leleevikevd....iykvePwdLpkkvkaeekewyfFskrdkkyatgkrknra........tksg 81 
                   lp+G++F+P+d el+ e+L++k+   +    + ++e+i++++    i++++P++Lp  v+++ ++++fF+++ ++yatgkrk+r+         ++ 
  EcC043273.40  52 LPAGVKFDPSDGELL-EHLAAKCGIGNsrqhMLIDEFIPTLEwnegICYTHPENLP-GVNKDGRSVHFFHRTMNAYATGKRKRRKihdqhnlnREDV 146
                   799************.999999877664554333445655534455**********.6778899********************8677777665599 PP

           NAM  82 yWkatgkdkevlskkgelvglkktLvfy..kgrapkgektdWvmheyrl 128
                   +W++tgk+k+v   +g ++g +k++v+y  +++ +k++k++Wvmh+y+l
  EcC043273.40 147 RWHKTGKTKPVAI-DGVHIGWQKIMVLYksSKKGSKATKSNWVMHQYHL 194
                   9************.99************4434777889*********98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019417.98E-3537213IPR003441NAC domain
PROSITE profilePS5100530.00352213IPR003441NAC domain
PfamPF023651.4E-1253194IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0006468Biological Processprotein phosphorylation
GO:0006487Biological Processprotein N-linked glycosylation
GO:0016020Cellular Componentmembrane
GO:0003677Molecular FunctionDNA binding
GO:0003830Molecular Functionbeta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity
GO:0004672Molecular Functionprotein kinase activity
GO:0005524Molecular FunctionATP binding
Sequence ? help Back to Top
Protein Sequence    Length: 377 aa     Download sequence    Send to blast
SWLVDGRSIA KKVKNATLST SCQIKDCGAN RECPNCHYFI DNTDVSPEWP GLPAGVKFDP  60
SDGELLEHLA AKCGIGNSRQ HMLIDEFIPT LEWNEGICYT HPENLPGVNK DGRSVHFFHR  120
TMNAYATGKR KRRKIHDQHN LNREDVRWHK TGKTKPVAID GVHIGWQKIM VLYKSSKKGS  180
KATKSNWVMH QYHLGADKEE KDGEYVVSKI FYQQPKETEK NNNNNKENNE SMDIDYQDVK  240
TLQTNPRTPK PNRLNPHQTE KFGLLDDVAE GDMKSSDQDI YKDIQLEDDE LYPEWLAGES  300
QPLEDFDFGY IDGLLFHEEP SGSHSPSNDR GCDLVPPTSL PEINEVVNEV VTDENATYGI  360
SELAKLDFDT PPDFLHP
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1128133KRKRRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor regulating the transcriptional activation response to gamma irradiation (PubMed:19549833). Required for stem-cell death induced by UVB or by gamma irradiation (PubMed:20634150). Not required for ATM activation, but participates in pathways governed by both ATM and ATR sensor kinases (PubMed:19549833). Involved in DNA damage response (DDR) system that regulates cell cycle arrest (PubMed:24399300). Functional homolog of animal p53 (PubMed:24736489). Regulates SMR5 and SMR7 transcription (PubMed:24399300). Regulates DNA repair and cytokinin signaling separately and plays a key role in controlling lateral root formation under genotoxic stress. {ECO:0000269|PubMed:19549833, ECO:0000269|PubMed:20634150, ECO:0000269|PubMed:24399300, ECO:0000305|PubMed:24736489}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Not induced by zeocin or ionizing radiation treatment. {ECO:0000269|PubMed:23907539}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010033337.10.0PREDICTED: NAC domain-containing protein 8 isoform X1
RefseqXP_010033338.10.0PREDICTED: NAC domain-containing protein 8 isoform X2
SwissprotQ6NQK25e-85NAC8_ARATH; SUPPRESSOR OF GAMMA RESPONSE 1
TrEMBLA0A059AGU70.0A0A059AGU7_EUCGR; Uncharacterized protein
STRINGXP_010033337.10.0(Eucalyptus grandis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM50452651
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G01600.17e-86NAC domain containing protein 44
Publications ? help Back to Top
  1. Yi D, et al.
    The Arabidopsis SIAMESE-RELATED cyclin-dependent kinase inhibitors SMR5 and SMR7 regulate the DNA damage checkpoint in response to reactive oxygen species.
    Plant Cell, 2014. 26(1): p. 296-309
    [PMID:24399300]
  2. Biever JJ,Brinkman D,Gardner G
    UV-B inhibition of hypocotyl growth in etiolated Arabidopsis thaliana seedlings is a consequence of cell cycle arrest initiated by photodimer accumulation.
    J. Exp. Bot., 2014. 65(11): p. 2949-61
    [PMID:24591052]
  3. Hu Z,Cools T,Kalhorzadeh P,Heyman J,De Veylder L
    Deficiency of the Arabidopsis helicase RTEL1 triggers a SOG1-dependent replication checkpoint in response to DNA cross-links.
    Plant Cell, 2015. 27(1): p. 149-61
    [PMID:25595823]
  4. Chen P,Umeda M
    DNA double-strand breaks induce the expression of flavin-containing monooxygenase and reduce root meristem size in Arabidopsis thaliana.
    Genes Cells, 2015. 20(8): p. 636-46
    [PMID:26033196]
  5. Sjogren CA,Bolaris SC,Larsen PB
    Aluminum-Dependent Terminal Differentiation of the Arabidopsis Root Tip Is Mediated through an ATR-, ALT2-, and SOG1-Regulated Transcriptional Response.
    Plant Cell, 2015. 27(9): p. 2501-15
    [PMID:26320227]
  6. Yoshiyama KO
    SOG1: a master regulator of the DNA damage response in plants.
    Genes Genet. Syst., 2016. 90(4): p. 209-16
    [PMID:26617076]
  7. Weimer AK, et al.
    The plant-specific CDKB1-CYCB1 complex mediates homologous recombination repair in Arabidopsis.
    EMBO J., 2016. 35(19): p. 2068-2086
    [PMID:27497297]
  8. Davis OM,Ogita N,Inagaki S,Takahashi N,Umeda M
    DNA damage inhibits lateral root formation by up-regulating cytokinin biosynthesis genes in Arabidopsis thaliana.
    Genes Cells, 2016. 21(11): p. 1195-1208
    [PMID:27658920]
  9. Pedroza-García JA, et al.
    Function of the Plant DNA Polymerase Epsilon in Replicative Stress Sensing, a Genetic Analysis.
    Plant Physiol., 2017. 173(3): p. 1735-1749
    [PMID:28153919]
  10. Horvath BM, et al.
    Arabidopsis RETINOBLASTOMA RELATED directly regulates DNA damage responses through functions beyond cell cycle control.
    EMBO J., 2017. 36(9): p. 1261-1278
    [PMID:28320736]
  11. Sjogren CA,Larsen PB
    SUV2, which encodes an ATR-related cell cycle checkpoint and putative plant ATRIP, is required for aluminium-dependent root growth inhibition in Arabidopsis.
    Plant Cell Environ., 2017. 40(9): p. 1849-1860
    [PMID:28556304]
  12. Yoshiyama KO,Kaminoyama K,Sakamoto T,Kimura S
    Increased Phosphorylation of Ser-Gln Sites on SUPPRESSOR OF GAMMA RESPONSE1 Strengthens the DNA Damage Response in Arabidopsis thaliana.
    Plant Cell, 2017. 29(12): p. 3255-3268
    [PMID:29208704]
  13. Johnson RA, et al.
    SUPPRESSOR OF GAMMA RESPONSE1 Links DNA Damage Response to Organ Regeneration.
    Plant Physiol., 2018. 176(2): p. 1665-1675
    [PMID:29222192]
  14. Ogita N, et al.
    Identifying the target genes of SUPPRESSOR OF GAMMA RESPONSE 1, a master transcription factor controlling DNA damage response in Arabidopsis.
    Plant J., 2018. 94(3): p. 439-453
    [PMID:29430765]
  15. Cao X, et al.
    Roles of MSH2 and MSH6 in cadmium-induced G2/M checkpoint arrest in Arabidopsis roots.
    Chemosphere, 2018. 201: p. 586-594
    [PMID:29533809]