PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lentibulariaceae; Genlisea

Family

C2H2

Protein Properties

Length: 197aa MW: 22460.4 Da PI: 9.5666

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
EPS63315.1	genome	LSMU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17.1	1.5e-05	20	42	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 + C+ C+k F r nL+ H r H EPS63315.1 20 FICEVCNKGFQRDQNLQLHRRGH 42 89*******************88 PP
2	zf-C2H2	14.4	0.00011	96	118	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC++C+k++ +s+ k H + + EPS63315.1 96 WKCEKCSKVYAVQSDWKAHSKIC 118 58*****************9876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	5.8E-7	19	42	No hit	No description
Gene3D	G3DSA:3.30.160.60	2.5E-6	19	42	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	10.866	20	42	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.026	20	42	IPR015880	Zinc finger, C2H2-like
Pfam	PF12171	2.2E-5	20	42	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE pattern	PS00028	0	22	42	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	1.7E-4	84	117	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	5.8E-7	91	116	No hit	No description
SMART	SM00355	120	96	116	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 197 aa Download sequence Send to blast
DPDAEVIALS PRTLLATNRF ICEVCNKGFQ RDQNLQLHRR GHNLPWKLKQ RSSRENRKRA 60 YVCPEPSCVH HHPSRALGDL TGIKKHFCRK HGEKKWKCEK CSKVYAVQSD WKAHSKICGT 120 REYRCDCGTL FTRKDSFITH RAFCDALAEE SARLSATTHG HGHGYGYGHS ILPENNAFHF 180 DHFSAAAAGN RHFPPPT

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	2e-36	92	161	3	72	Zinc finger protein JACKDAW
5b3h_F	2e-36	92	161	3	72	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that regulates tissue boundaries and asymmetric cell division (PubMed:17785527, PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:17785527, PubMed:25829440). Interacts with the SCR and MGP promoters (PubMed:21935722). Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors (PubMed:21935722). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Positively involved in gibberellic acid (GA) signaling (PubMed:24821766). {ECO:0000269\|PubMed:17785527, ECO:0000269\|PubMed:21935722, ECO:0000269\|PubMed:24821766, ECO:0000269\|PubMed:25829440}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by the transcription factor JKD, and down-regulated by SHR, SCR and itself. {ECO:0000269\|PubMed:21935722}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011082586.1	1e-109	protein indeterminate-domain 12
Swissprot	Q9ZWA6	1e-103	IDD3_ARATH; Zinc finger protein MAGPIE
TrEMBL	S8C8Z6	1e-145	S8C8Z6_9LAMI; Uncharacterized protein (Fragment)
STRING	VIT_00s0179g00170.t01	1e-107	(Vitis vinifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA103	24	350

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G02670.1	1e-104	indeterminate(ID)-domain 12

Publications ? help Back to Top
Leushkin EV, et al. The miniature genome of a carnivorous plant Genlisea aurea contains a low number of genes and short non-coding sequences. BMC Genomics, 2013. 14: p. 476 [PMID:23855885] Muñoz-Strale D,León G Identification of two highly specific pollen promoters using transcriptomic data. Plant Physiol. Biochem., 2014. 83: p. 292-9 [PMID:25208507] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755]