PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lentibulariaceae; Genlisea

Family

C2H2

Protein Properties

Length: 212aa MW: 23816.1 Da PI: 9.0999

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
EPS62601.1	genome	LSMU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	18.7	4.7e-06	42	64	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H EPS62601.1 42 FVCEICNKGFQRDQNLQLHRRGH 64 89*******************88 PP
2	zf-C2H2	12.9	0.00032	118	140	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC +C+k + +s+ k H + + EPS62601.1 118 WKCDKCSKKYAVQSDWKAHSKIC 140 58*****************9876 PP
3	zf-C2H2	12.7	0.00038	148	166	5	23
TTTEEESSHHHHHHHHHHT CS zf-C2H2 5 dCgksFsrksnLkrHirtH 23 Cg++Fsrk+++++H + EPS62601.1 148 GCGTTFSRKDSFMTHKAFC 166 6**************8765 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	5.4E-6	41	64	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	3.24E-7	41	64	No hit	No description
SMART	SM00355	0.017	42	64	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.949	42	64	IPR007087	Zinc finger, C2H2
Pfam	PF12171	2.7E-5	42	64	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE pattern	PS00028	0	44	64	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	2.4E-4	106	139	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	3.24E-7	113	138	No hit	No description
SMART	SM00355	150	118	138	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 212 aa Download sequence Send to blast
SGDSSSGPQP TSKRKRNLPG NPDPDAEVIA LSPTTLLATN RFVCEICNKG FQRDQNLQLH 60 RRGHNLPWKL RQRSTKEVKK RVYICPETSC IHHDPCRALG DLTGIKKHFC RKHGEKKWKC 120 DKCSKKYAVQ SDWKAHSKIC GTREYRCGCG TTFSRKDSFM THKAFCDVLA EENEREPPPP 180 PPPILNEDNT TEAVSSPPSS EATIPTVPPL IP

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	6e-32	114	175	3	64	Zinc finger protein JACKDAW
5b3h_F	6e-32	114	175	3	64	Zinc finger protein JACKDAW
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_007204325.1	1e-113	protein indeterminate-domain 2
Swissprot	Q9SCQ6	1e-111	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	S8CDN6	1e-156	S8CDN6_9LAMI; Uncharacterized protein (Fragment)
STRING	EMJ05524	1e-112	(Prunus persica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA103	24	350

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	1e-102	indeterminate(ID)-domain 2

Publications ? help Back to Top
Leushkin EV, et al. The miniature genome of a carnivorous plant Genlisea aurea contains a low number of genes and short non-coding sequences. BMC Genomics, 2013. 14: p. 476 [PMID:23855885] Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]