PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Aegilops

Family

C2H2

Protein Properties

Length: 487aa MW: 51228.6 Da PI: 9.604

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
EMT33634	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17.5	1.1e-05	86	108	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C+ C+k F r nL+ H r H EMT33634 86 FVCEVCNKGFQREQNLQLHRRGH 108 89*******************88 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	6.5E-6	85	108	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	1.25E-7	85	108	No hit	No description
SMART	SM00355	0.0041	86	108	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	11.094	86	108	IPR007087	Zinc finger, C2H2
Pfam	PF12171	3.1E-5	86	108	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE pattern	PS00028	0	88	108	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	4.7E-4	151	184	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	1.25E-7	158	183	No hit	No description
SMART	SM00355	210	163	183	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 487 aa Download sequence Send to blast
MASNSSAAAV AALFGIREGH QQDQMKPLLA QHQRQHVVAP PSALLTAGPD QAAAAAPPVK 60 KKRTMPDPDA EVIALSPKTL MATNRFVCEV CNKGFQREQN LQLHRRGHNL PWKLKQKDPN 120 QVQRRRVYLC PEPTCVHHEP GRALGDLTGI KKHFCRKHGE KKWKCDKCAK RYAVQSDWKA 180 HSKICGTREY RCDCGTLFSR RDSFITHRAF CDALAQESAR LPPGAGHLYG ATRAANMALS 240 LSQGGLSLHD AHGQYHQASS DLLRFGGGGG GGMAARLDHL LSSSNAPSFR HLPPPQAPPF 300 HLGSAQEFVD GNGSPAFLHG KPFHGLMQLP DLQGNGSGGT SSSAPGLFNL GYIANSANSS 360 GTSSHGHASQ GHMANDQISE GGGGGGAGSE NSGAAFFSAG GNFSGGDHQV APSGMYNEQS 420 VMMPQMSATA LLQKAAQMGS STSADGGGAS VFGGFMGSSV PQGRAPMGTF PVATTRLLPR 480 GCTTSNP

Sequence ? help Back to Top

Protein Sequence Length: 487 aa Download sequence Send to blast

MASNSSAAAV AALFGIREGH QQDQMKPLLA QHQRQHVVAP PSALLTAGPD QAAAAAPPVK  60
KKRTMPDPDA EVIALSPKTL MATNRFVCEV CNKGFQREQN LQLHRRGHNL PWKLKQKDPN  120
QVQRRRVYLC PEPTCVHHEP GRALGDLTGI KKHFCRKHGE KKWKCDKCAK RYAVQSDWKA  180
HSKICGTREY RCDCGTLFSR RDSFITHRAF CDALAQESAR LPPGAGHLYG ATRAANMALS  240
LSQGGLSLHD AHGQYHQASS DLLRFGGGGG GGMAARLDHL LSSSNAPSFR HLPPPQAPPF  300
HLGSAQEFVD GNGSPAFLHG KPFHGLMQLP DLQGNGSGGT SSSAPGLFNL GYIANSANSS  360
GTSSHGHASQ GHMANDQISE GGGGGGAGSE NSGAAFFSAG GNFSGGDHQV APSGMYNEQS  420
VMMPQMSATA LLQKAAQMGS STSADGGGAS VFGGFMGSSV PQGRAPMGTF PVATTRLLPR  480
GCTTSNP

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	4e-34	159	221	3	65	Zinc finger protein JACKDAW
5b3h_F	4e-34	159	221	3	65	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that may act a transcriptional activator of nuclear-encoded photosynthetic gene expression (Probable). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). {ECO:0000269\|PubMed:24821766, ECO:0000305\|PubMed:19726569}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated by gibberellin. {ECO:0000305\|PubMed:17933900}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK359132	0.0	AK359132.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv1090F15.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020179604.1	0.0	protein indeterminate-domain 4, chloroplastic-like
Swissprot	Q8GYC1	1e-109	IDD4_ARATH; Protein indeterminate-domain 4, chloroplastic
TrEMBL	N1R4T4	0.0	N1R4T4_AEGTA; Zinc finger protein MAGPIE
STRING	EMT33634	0.0	(Aegilops tauschii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP1733	37	98

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G03840.1	1e-103	C2H2 family protein

Publications ? help Back to Top
Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755]