PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID EMT19401
Organism
Aegilops tauschii
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Aegilops
Family E2F/DP
Protein Properties Length: 508aa    MW: 56100.3 Da    PI: 5.1735
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
EMT19401genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP82.72.9e-26131196171
   E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
               r+++sL+llt+kfl+ll+ ++ g+v+ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+irwkg
  EMT19401 131 RYDSSLGLLTKKFLNLLKGAPGGMVDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNNIRWKG 196
               6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.7E-28129197IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.18E-16131194IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.0E-34131196IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.3E-23133196IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146603.20E-50207313No hitNo description
SuperFamilySSF1440745.75E-33208313No hitNo description
PfamPF164212.5E-33212311IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 508 aa     Download sequence    Send to blast
MAAAAGGTSS EGAARVLLQR YQPFGSPPGD SRQCGPADGG GSAEMTEAVV LRTPLKRKHN  60
REDNEVTESN DWMMSPGYAN ATNSPIPTPP SGKGSKMSAK PKAAKGQKSC PQTPLFSGSP  120
GNPATPVGGC RYDSSLGLLT KKFLNLLKGA PGGMVDLNNA AETLEVQKRR IYDITNVLEG  180
IGLIEKKLKN NIRWKGIDDS RPGEVSDDMS ILQGDIEALT LQEHSLDGQI SEMRDKLREL  240
TEDENNQKWL YVTEDDIKSL PCFQNQTLIA IKAPHGTTLE VPDPDEVNDY PQRRYRIVLR  300
STMGPIDVYL VSQFEEMSGM ETPPRSAQTI SMDYLENPRT PLATGSNKDV EMENVQQGLI  360
MPPDAPTTQD IGGMMKIVPS ELDTDADYWL LSDTGYSIPC YDVKPLDSLT RIQQMWSGKE  420
STSTRRISWK LAHLGSKISR PLKWWIIPRA LAEEDLKHGG KYHSHTWEFF VSCCGLSMAD  480
QFRTETREQR FQGGCCDVHT DGNLVPCQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A2e-22123197274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00661PBMTransfer from Pp3c1_6880Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020177970.10.0transcription factor E2FA-like
SwissprotQ9FNY01e-111E2FA_ARATH; Transcription factor E2FA
TrEMBLR7WAV20.0R7WAV2_AEGTA; Transcription factor E2F3
STRINGEMT194010.0(Aegilops tauschii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP62537148
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-105E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]