PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Aegilops

Family

MYB

Protein Properties

Length: 256aa MW: 28312.9 Da PI: 8.1625

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
EMT12739	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	54.4	2.9e-17	14	61	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg+WT+eEd++lv ++ +G +W++ ++ g+ R++k+c++rw +yl EMT12739 14 RGPWTPEEDKILVAHIHSHGHSNWRALPKQAGLLRCGKSCRLRWINYL 61 89****************************99**********97 PP
2	Myb_DNA-binding	53	7.7e-17	67	112	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg++T eE++ +++++++lG++ W++Ia++++ gRt++++k+ w+++l EMT12739 67 RGNFTDEEEQSIIQLHQLLGNR-WSAIAARLP-GRTDNEIKNVWHTHL 112 89******************.*****.**********986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	5.3E-25	5	64	IPR009057	Homeodomain-like
PROSITE profile	PS51294	15.816	9	61	IPR017930	Myb domain
SuperFamily	SSF46689	5.14E-30	10	108	IPR009057	Homeodomain-like
SMART	SM00717	1.7E-13	13	63	IPR001005	SANT/Myb domain
Pfam	PF00249	1.6E-15	14	61	IPR001005	SANT/Myb domain
CDD	cd00167	1.53E-10	16	61	No hit	No description
PROSITE profile	PS51294	25.243	62	116	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	9.3E-27	65	116	IPR009057	Homeodomain-like
SMART	SM00717	1.7E-14	66	114	IPR001005	SANT/Myb domain
Pfam	PF00249	1.1E-15	67	112	IPR001005	SANT/Myb domain
CDD	cd00167	2.11E-10	69	112	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 256 aa Download sequence Send to blast
MGRAPCCEKM GLKRGPWTPE EDKILVAHIH SHGHSNWRAL PKQAGLLRCG KSCRLRWINY 60 LRPDIKRGNF TDEEEQSIIQ LHQLLGNRWS AIAARLPGRT DNEIKNVWHT HLKKRLDPSA 120 QEQHQEAKKR KKPAAAARKR EGKVKMRKLD ALTAKAAPVL SSPERSVSST LTESTSTASA 180 AAEQHGNSGS SASASASVKE ECFTSSEESE EFQIDESFWS ETLSMPLDDI NDVCMEPHDA 240 FGKPAGADGA LDLPQV

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1a5j_A	6e-27	12	117	5	109	B-MYB
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	112	131	KKRLDPSAQEQHQEAKKRKK
2	127	131	KKRKK
3	130	147	KKPAAAARKREGKVKMRK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in cold stress response (PubMed:14675437, PubMed:20807373, PubMed:22246661). Regulates positively the expression of genes involved in reactive oxygen species (ROS) scavenging such as peroxidase and superoxide dismutase during cold stress. Transactivates a complex gene network that have major effects on stress tolerance and panicle development (PubMed:20807373). {ECO:0000269\|PubMed:14675437, ECO:0000269\|PubMed:20807373, ECO:0000269\|PubMed:22246661}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By cold stress. {ECO:0000269\|PubMed:14675437, ECO:0000269\|PubMed:20807373, ECO:0000269\|Ref.2}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AB252147	0.0	AB252147.1 Triticum aestivum Tamyb7 mRNA for myb-related protein, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020164748.1	1e-155	myb-related protein Myb4-like
Swissprot	Q7XBH4	1e-105	MYB4_ORYSJ; Transcription factor MYB4
TrEMBL	N1QUZ4	0.0	N1QUZ4_AEGTA; Myb-related protein Myb4
STRING	EMT12739	0.0	(Aegilops tauschii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP79	38	563

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23250.1	2e-77	myb domain protein 15

Publications ? help Back to Top
Park MR, et al. Supra-optimal expression of the cold-regulated OsMyb4 transcription factor in transgenic rice changes the complexity of transcriptional network with major effects on stress tolerance and panicle development. Plant Cell Environ., 2010. 33(12): p. 2209-30 [PMID:20807373] Soltész A, et al. The rice Osmyb4 gene enhances tolerance to frost and improves germination under unfavourable conditions in transgenic barley plants. J. Appl. Genet., 2012. 53(2): p. 133-43 [PMID:22246661]