PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Dichantheliinae; Dichanthelium

Family

MYB

Protein Properties

Length: 267aa MW: 29234.7 Da PI: 5.9781

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Do021522.1	genome	Dichan	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	58.9	1.1e-18	14	61	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg+W++eEd++l++++ q G ++W++ +r+ g+ R++k+c++rw +yl Do021522.1 14 RGAWSPEEDQRLLEYISQNGHPNWRALPRHAGLLRCGKSCRLRWINYL 61 89****************************99**********97 PP
2	Myb_DNA-binding	50.6	4.5e-16	67	111	1	47
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 rg+++++E+ l+v+++++lG++ W++Ia+ ++ gRt++++k+ w+++ Do021522.1 67 RGNFSADEEALIVRLHHELGNR-WSAIAAQLP-GRTDNEIKNVWHTH 111 89******************.*****.*********987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	1.8E-23	5	64	IPR009057	Homeodomain-like
PROSITE profile	PS51294	17.377	9	61	IPR017930	Myb domain
SuperFamily	SSF46689	2.92E-28	12	108	IPR009057	Homeodomain-like
SMART	SM00717	2.8E-13	13	63	IPR001005	SANT/Myb domain
Pfam	PF00249	5.6E-16	14	61	IPR001005	SANT/Myb domain
CDD	cd00167	5.08E-11	16	61	No hit	No description
PROSITE profile	PS51294	24.32	62	116	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	2.1E-25	65	116	IPR009057	Homeodomain-like
SMART	SM00717	8.1E-14	66	114	IPR001005	SANT/Myb domain
Pfam	PF00249	8.1E-15	67	111	IPR001005	SANT/Myb domain
CDD	cd00167	1.23E-10	69	112	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 267 aa Download sequence Send to blast
MGRAPCCEKD GLRRGAWSPE EDQRLLEYIS QNGHPNWRAL PRHAGLLRCG KSCRLRWINY 60 LRPDIKRGNF SADEEALIVR LHHELGNRWS AIAAQLPGRT DNEIKNVWHT HIKKRLEGDA 120 AAGGRPKQKA RKSKAAAAKE ATAADSSEQQ PFMTASPGLS SSVSSGVTTF STATESTDAG 180 TTSARLQLGA TTKAADMELE SFSSAEFPPI DDSFWSSPDV VDMGLGVMDQ ELGLAGPPSS 240 STRDEDMEFW LNMLMEAGDM RDLPSFL

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1a5j_A	1e-25	12	117	5	109	B-MYB
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in cold stress response (PubMed:14675437, PubMed:20807373, PubMed:22246661). Regulates positively the expression of genes involved in reactive oxygen species (ROS) scavenging such as peroxidase and superoxide dismutase during cold stress. Transactivates a complex gene network that have major effects on stress tolerance and panicle development (PubMed:20807373). {ECO:0000269\|PubMed:14675437, ECO:0000269\|PubMed:20807373, ECO:0000269\|PubMed:22246661}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Do021522.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By cold stress. {ECO:0000269\|PubMed:14675437, ECO:0000269\|PubMed:20807373, ECO:0000269\|Ref.2}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HF679408	1e-157	HF679408.1 Saccharum hybrid cultivar Co 86032 mRNA for ScMYB2 protein.
GenBank	JQ255478	1e-157	JQ255478.1 Saccharum hybrid cultivar Co 86032 MYB46 (MYB46) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004982863.1	1e-143	transcription factor MYB4
Swissprot	Q7XBH4	2e-77	MYB4_ORYSJ; Transcription factor MYB4
TrEMBL	A0A1E5V0P3	0.0	A0A1E5V0P3_9POAL; Myb-related protein Myb4
STRING	Si040527m	1e-143	(Setaria italica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP79	38	563

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G31180.1	2e-72	myb domain protein 14

Publications ? help Back to Top
Park MR, et al. Supra-optimal expression of the cold-regulated OsMyb4 transcription factor in transgenic rice changes the complexity of transcriptional network with major effects on stress tolerance and panicle development. Plant Cell Environ., 2010. 33(12): p. 2209-30 [PMID:20807373] Soltész A, et al. The rice Osmyb4 gene enhances tolerance to frost and improves germination under unfavourable conditions in transgenic barley plants. J. Appl. Genet., 2012. 53(2): p. 133-43 [PMID:22246661]