PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Dichantheliinae; Dichanthelium

Family

bHLH

Protein Properties

Length: 435aa MW: 45704.1 Da PI: 7.9456

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Do002406.1	genome	Dichan	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	29.4	1.4e-09	289	336	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h+ +Er RR++i +++ L++l+P + +k + Ka +L + ++Y++sLq Do002406.1 289 SHSLAERVRREKISQRMKLLQDLVPGC----NKVVGKAVMLDEIINYVQSLQ 336 8***********************9....677***************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00083	2.68E-10	283	340	No hit	No description
SuperFamily	SSF47459	1.18E-16	283	354	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	15.256	285	335	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	9.2E-17	287	353	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.3E-6	289	336	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.3E-10	291	341	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009637	Biological Process	response to blue light
GO:0005634	Cellular Component	nucleus
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 435 aa Download sequence Send to blast
MNCGPPDQLP PASAPSCFLN LNWDQSMAAA AAGDHLDPAL SSMVSSPASN STAAAATDGL 60 ALHGISPQPQ YGGTPLSSPP KLNLSMMGQF HHYPTPQVGG AGPGGLPILE NLMPMGHLDQ 120 FLADPGFAER AARLSSFDGR PGGSGYGGAV AGQFGLPDAC PVGALNELEL GNGRDESSVS 180 DPASASAEMA LKGPSDGNAK KRKASGKGKG KDGPGSTAAK DLAKEESSGK RCKSADESNG 240 AEDNSTKGKA AQSNSESGGK KQGKDASKPP EPPKDYIHVR ARRGEATDSH SLAERVRREK 300 ISQRMKLLQD LVPGCNKVVG KAVMLDEIIN YVQSLQRQVE FLSMKLATVN PQLDFNNLPN 360 LLPKDMNSQH PFLNGVSDAA SQVGTFWQDD LQSVVHMDIG QSQEIAATSS NSYNAVLPTS 420 GKHARFRFRL RRALR

Sequence ? help Back to Top

Protein Sequence Length: 435 aa Download sequence Send to blast

MNCGPPDQLP PASAPSCFLN LNWDQSMAAA AAGDHLDPAL SSMVSSPASN STAAAATDGL  60
ALHGISPQPQ YGGTPLSSPP KLNLSMMGQF HHYPTPQVGG AGPGGLPILE NLMPMGHLDQ  120
FLADPGFAER AARLSSFDGR PGGSGYGGAV AGQFGLPDAC PVGALNELEL GNGRDESSVS  180
DPASASAEMA LKGPSDGNAK KRKASGKGKG KDGPGSTAAK DLAKEESSGK RCKSADESNG  240
AEDNSTKGKA AQSNSESGGK KQGKDASKPP EPPKDYIHVR ARRGEATDSH SLAERVRREK  300
ISQRMKLLQD LVPGCNKVVG KAVMLDEIIN YVQSLQRQVE FLSMKLATVN PQLDFNNLPN  360
LLPKDMNSQH PFLNGVSDAA SQVGTFWQDD LQSVVHMDIG QSQEIAATSS NSYNAVLPTS  420
GKHARFRFRL RRALR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds DNA to G box 5'-CACGTG-3' and to E-box 5'-CANNTG-3' (By similarity). Binds to chromatin DNA of the FT gene and promotes its expression, and thus triggers flowering in response to blue light (PubMed:24130508). {ECO:0000250\|UniProtKB:Q8GY61, ECO:0000269\|PubMed:24130508}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00036	PBM	Transfer from AT5G48560	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Do002406.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004971039.1	0.0	transcription factor bHLH77
Swissprot	Q9FJL4	2e-59	BH078_ARATH; Transcription factor bHLH78
TrEMBL	A0A1E5V5W5	0.0	A0A1E5V5W5_9POAL; Transcription factor bHLH77
STRING	Si001242m	0.0	(Setaria italica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP919	38	137

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23690.1	7e-54	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281]