PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID DCAR_025351
Organism
Daucus carota
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Apiales; Apiineae; Apiaceae; Apioideae; Scandiceae; Daucinae; Daucus
Family C2H2
Protein Properties Length: 366aa    MW: 41806.9 Da    PI: 6.9729
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
DCAR_025351genomeARS-USDAView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.40.0004979101323
                  ET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                  C+   Cgk+F +   L++H   H
  DCAR_025351  79 CSyeGCGKTFIDAGALRKHSHIH 101
                  77779**************7766 PP
2zf-C2H2163.5e-05106130123
                  EEET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                  y+C+  +Cgk F ++s LkrH   H
  DCAR_025351 106 YVCHyeNCGKKFLDSSKLKRHFLIH 130
                  9********************8877 PP
3zf-C2H221.75.2e-07136160123
                  EEET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                  ++Cp   Cgk Fs   nL++H++tH
  DCAR_025351 136 FVCPheGCGKAFSLDFNLRSHMKTH 160
                  89**********************9 PP
4zf-C2H214.40.00011166191123
                  EEET..TTTEEESSHHHHHHHHHH.T CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                  + Cp   Cgk++ + + Lk+H ++ H
  DCAR_025351 166 HICPypECGKRYAHEYKLKNHVMSqH 191
                  679999***************99988 PP
5zf-C2H213.20.00027231256123
                  EEET..TTTEEESSHHHHHHHHHH.T CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                  y Cp   C k + + + L+ H+r+ H
  DCAR_025351 231 YACPyeGCEKAYIHEYKLNLHLRReH 256
                  89*********************999 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.609.0E-1472103IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.003277101IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.78377106IPR007087Zinc finger, C2H2
PROSITE patternPS00028079101IPR007087Zinc finger, C2H2
SuperFamilySSF576673.37E-880130No hitNo description
Gene3DG3DSA:3.30.160.606.1E-14104126IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.011106130IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015714.17106135IPR007087Zinc finger, C2H2
PROSITE patternPS000280108130IPR007087Zinc finger, C2H2
SuperFamilySSF576673.03E-13117169No hitNo description
Gene3DG3DSA:3.30.160.602.0E-19127162IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015711.822136165IPR007087Zinc finger, C2H2
SMARTSM003553.1E-4136160IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280138160IPR007087Zinc finger, C2H2
PROSITE profilePS501579.099166196IPR007087Zinc finger, C2H2
SMARTSM003550.036166191IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.607.0E-7166187IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280168191IPR007087Zinc finger, C2H2
SuperFamilySSF576675.67E-6223254No hitNo description
Gene3DG3DSA:3.30.160.608.4E-9225254IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0097231256IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.762231261IPR007087Zinc finger, C2H2
PROSITE patternPS000280233256IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 366 aa     Download sequence    Send to blast
MEMHTHHSIF ERRPIIKSKA PAVKWFKEWV PQDVVATGGK CLVLKWVTEA TLKALKEKIK  60
EPDTAEPEPE PTTEVLFLCS YEGCGKTFID AGALRKHSHI HGERQYVCHY ENCGKKFLDS  120
SKLKRHFLIH TGERDFVCPH EGCGKAFSLD FNLRSHMKTH SQANYHICPY PECGKRYAHE  180
YKLKNHVMSQ HEKQSVVDVP KYVPPPAPEK PAKAVKASTT THATATAERP YACPYEGCEK  240
AYIHEYKLNL HLRREHPGHF PDENAKNAQS NADNDMDEGS DQDVYANKRG SSKPQKQNRP  300
KPSIKLPPSK VPQRKSMTAA PTNMNVTVVR KPWPVKEERY EEEDSEETEE DGENDDDDEQ  360
TEYED*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C3e-34791898116PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017215268.10.0PREDICTED: uncharacterized zinc finger protein At4g06634
SwissprotQ2V3L31e-145YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A164U0R50.0A0A164U0R5_DAUCS; Uncharacterized protein
STRINGMigut.B00804.1.p0.0(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA73432332
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.11e-134C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]