PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Apiales; Apiineae; Apiaceae; Apioideae; Scandiceae; Daucinae; Daucus

Family

C2H2

Protein Properties

Length: 432aa MW: 47960 Da PI: 9.3102

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
DCAR_002807	genome	ARS-USDA	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17.5	1.2e-05	6	28	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H DCAR_002807 6 FVCEICNKGFQRDQNLQLHRRGH 28 89*******************88 PP
2	zf-C2H2	16.5	2.4e-05	82	104	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC +C+k++ +s+ k H++t+ DCAR_002807 82 WKCDKCSKRYAVQSDWKAHQKTC 104 58*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	3.79E-8	5	28	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.4E-5	5	28	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.017	6	28	IPR015880	Zinc finger, C2H2-like
Pfam	PF12171	6.7E-5	6	28	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE profile	PS50157	10.949	6	28	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	8	28	IPR007087	Zinc finger, C2H2
SMART	SM00355	120	47	77	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	2.2E-5	70	103	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	3.79E-8	77	103	No hit	No description
SMART	SM00355	89	82	102	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 432 aa Download sequence Send to blast
MATNRFVCEI CNKGFQRDQN LQLHRRGHNL PWKLKQRTTT EVRKRVYICP ETSCVHHNPA 60 RALGDLTGIK KHFSRKHGEK KWKCDKCSKR YAVQSDWKAH QKTCGTREYK CDCGTIFSRR 120 DSFITHRAFC DALAEENNKV NQGLMQSMGS NLQPQMPHDM NNNTSMALMS DFNNYDQKNQ 180 LKSMSQDMQF KPMNIATGMF SSNSGSLFGG PRNNVQSSSS GLQLSSNSPS SFSYLQDNKN 240 GPNNLLGAAN MSATALLQKA AQMGATASNN TISSPMIQKT FGNTGPMIDN ANTSFENVTS 300 KPDETSFVGL TGGAFTTQLM QKAPHQMFAS GPSSSPSMTD MAMFGDMLMG NEQGFMKHME 360 HLEDGMSQNP IGPSRFGVNQ GSSRGNDTLT VDFLGLGGGS RPHNLHEQQQ QQRMQMMNPF 420 QQQLEKPIWD V*

Sequence ? help Back to Top

Protein Sequence Length: 432 aa Download sequence Send to blast

MATNRFVCEI CNKGFQRDQN LQLHRRGHNL PWKLKQRTTT EVRKRVYICP ETSCVHHNPA  60
RALGDLTGIK KHFSRKHGEK KWKCDKCSKR YAVQSDWKAH QKTCGTREYK CDCGTIFSRR  120
DSFITHRAFC DALAEENNKV NQGLMQSMGS NLQPQMPHDM NNNTSMALMS DFNNYDQKNQ  180
LKSMSQDMQF KPMNIATGMF SSNSGSLFGG PRNNVQSSSS GLQLSSNSPS SFSYLQDNKN  240
GPNNLLGAAN MSATALLQKA AQMGATASNN TISSPMIQKT FGNTGPMIDN ANTSFENVTS  300
KPDETSFVGL TGGAFTTQLM QKAPHQMFAS GPSSSPSMTD MAMFGDMLMG NEQGFMKHME  360
HLEDGMSQNP IGPSRFGVNQ GSSRGNDTLT VDFLGLGGGS RPHNLHEQQQ QQRMQMMNPF  420
QQQLEKPIWD V*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	1e-33	78	151	3	71	Zinc finger protein JACKDAW
5b3h_F	1e-33	78	151	3	71	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017221451.1	0.0	PREDICTED: protein indeterminate-domain 2-like
Swissprot	Q9SCQ6	8e-97	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A166HEH4	0.0	A0A166HEH4_DAUCS; Uncharacterized protein
STRING	EOX94991	0.0	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA103	24	350

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	1e-97	indeterminate(ID)-domain 2

Link Out ? help Back to Top
Phytozome	DCAR_002807

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]