PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cucsa.395990.2
Common NameCsa_2G356640, LOC105434642
Organism
Cucumis sativus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family bHLH
Protein Properties Length: 380aa    MW: 41336.8 Da    PI: 4.8081
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cucsa.395990.2genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH50.92.7e-16200246455
                     HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
             HLH   4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                      hn+ E+rRR+riN+++  L+ l+P++      K +Ka++L +A+eY+k+Lq
  Cucsa.395990.2 200 VHNMSEKRRRRRINEKMKALQNLIPNS-----NKTDKASMLDEAIEYLKQLQ 246
                     6*************************7.....5******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000831.99E-18192250No hitNo description
SuperFamilySSF474591.57E-20193256IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.6E-20193256IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088817.949196245IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000109.4E-14200246IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003534.5E-18202251IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 380 aa     Download sequence    Send to blast
MADLYGTSPS SDVVGLPHDP EDFSSFINHH LQTTTSSASS PSCVSFKNKF MPLLHSQPPW  60
HSSPMFSRRP DSTSVPGMSC MLDFPEDRLQ SSRVLNHALS DCNVRDVRFA DASYLAVNST  120
CGGVKLSDPG DFLKESSDNA FSSSGAVDSD TNAPLKRRGL SSENDLGDFS CDSEGGDLPE  180
VPSSTNLPRN SSKRSRSAEV HNMSEKRRRR RINEKMKALQ NLIPNSNKTD KASMLDEAIE  240
YLKQLQLQVQ MLSMRNGLSL QPMCLPGMLQ PIQLPQMGLD YDVGNAFLTS RRGIDTSSTR  300
NEGCPMQSTF NLTNKCNLSD QSIAIPSVPN TTTSETAFGF EPTIQGYDGE FNLSSDFKDG  360
EPAAQLDCAQ TGNESTDAS*
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1205210KRRRRR
2205211KRRRRRI
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that plays a role in floral organogenesis. Promotes the growth of carpel margins and of pollen tract tissues derived from them. {ECO:0000269|PubMed:10225997, ECO:0000269|Ref.8}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by the A class gene AP2 in the first whorl and by ARF3/ETT in gynoecium. {ECO:0000269|PubMed:11245574}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818230.0LN681823.1 Cucumis melo genomic scaffold, anchoredscaffold00014.
GenBankLN7132570.0LN713257.1 Cucumis melo genomic chromosome, chr_3.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011649579.10.0PREDICTED: transcription factor SPATULA-like
SwissprotQ9FUA43e-38SPT_ARATH; Transcription factor SPATULA
TrEMBLA0A0A0LKR90.0A0A0A0LKR9_CUCSA; Uncharacterized protein
STRINGXP_004172700.10.0(Cucumis sativus)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G36930.11e-40bHLH family protein
Publications ? help Back to Top
  1. Ren Y, et al.
    An integrated genetic and cytogenetic map of the cucumber genome.
    PLoS ONE, 2009. 4(6): p. e5795
    [PMID:19495411]
  2. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  3. Guo S, et al.
    Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types.
    BMC Genomics, 2010. 11: p. 384
    [PMID:20565788]
  4. Li Z, et al.
    RNA-Seq improves annotation of protein-coding genes in the cucumber genome.
    BMC Genomics, 2011. 12: p. 540
    [PMID:22047402]
  5. Pabón-Mora N,Wong GK,Ambrose BA
    Evolution of fruit development genes in flowering plants.
    Front Plant Sci, 2014. 5: p. 300
    [PMID:25018763]
  6. Moubayidin L,Ostergaard L
    Dynamic control of auxin distribution imposes a bilateral-to-radial symmetry switch during gynoecium development.
    Curr. Biol., 2014. 24(22): p. 2743-8
    [PMID:25455035]
  7. Pfannebecker KC,Lange M,Rupp O,Becker A
    Seed Plant-Specific Gene Lineages Involved in Carpel Development.
    Mol. Biol. Evol., 2017. 34(4): p. 925-942
    [PMID:28087776]
  8. Zumajo-Cardona C,Ambrose BA,Pabón-Mora N
    Evolution of the SPATULA/ALCATRAZ gene lineage and expression analyses in the basal eudicot, Bocconia frutescens L. (Papaveraceae).
    Evodevo, 2017. 8: p. 5
    [PMID:28331573]
  9. Reyes-Olalde JI, et al.
    The bHLH transcription factor SPATULA enables cytokinin signaling, and both activate auxin biosynthesis and transport genes at the medial domain of the gynoecium.
    PLoS Genet., 2017. 13(4): p. e1006726
    [PMID:28388635]
  10. Wu M, et al.
    SPATULA regulates floral transition and photomorphogenesis in a PHYTOCHROME B-dependent manner in Arabidopsis.
    Biochem. Biophys. Res. Commun., 2018. 503(4): p. 2380-2385
    [PMID:29966653]