PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cucsa.394390.1
Organism
Cucumis sativus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family HB-other
Protein Properties Length: 320aa    MW: 36313.1 Da    PI: 5.1386
Description HB-other family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cucsa.394390.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox27.36.4e-092612942255
                     SSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS
        Homeobox  22 nrypsaeereeLAkklgLterqVkvWFqNrRake 55 
                      +yp+++++  LA+ +gL+ +q+ +WF N+R ++
  Cucsa.394390.1 261 WPYPTEADKVALAETTGLDPKQINNWFINQRKRH 294
                     69*****************************885 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM012558.7E-2376120IPR005540KNOX1
PfamPF037905.7E-2279119IPR005540KNOX1
SMARTSM012564.0E-21126177IPR005541KNOX2
PfamPF037917.1E-22130175IPR005541KNOX2
SMARTSM011885.3E-4214235IPR005539ELK domain
PfamPF037895.0E-7215235IPR005539ELK domain
PROSITE profilePS5007112.406234297IPR001356Homeobox domain
SuperFamilySSF466891.15E-18235306IPR009057Homeodomain-like
SMARTSM003895.9E-12236301IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.606.2E-27239298IPR009057Homeodomain-like
CDDcd000861.34E-11248298No hitNo description
PfamPF059209.7E-17254293IPR008422Homeobox KN domain
PROSITE patternPS000270272295IPR017970Homeobox, conserved site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010073Biological Processmeristem maintenance
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 320 aa     Download sequence    Send to blast
MEDNMYGMPK SFLPPDNLIL PLDYQSLLSS SNYRRDPIPM FGSHQLLSRP TSAISQAEPP  60
STTTPDFPIP REDLLSVTKA KIVSHPTYPR LLHAYIDCQK VGAPPEVACL LEEIRRENDS  120
QEQNGISTCF GADPELDEFM EAYCDMLVKY KSDLSRPFHE AFSFLNNIQL QLCNLGAPAS  180
TSTPSNEDAM SSDDELNCGE RELQDGQMRL EDKGLKDMLL SRFGGHIGTL KLEFSKKKKK  240
GKLPKEGRKV LLEWWDVHYK WPYPTEADKV ALAETTGLDP KQINNWFINQ RKRHWKPSES  300
MQFGNMDNAG EQFYARLDS*
Functional Description ? help Back to Top
Source Description
UniProtPlays a role in meristem function. Contributes to the shoot apical meristem (SAM) maintenance and organ separation by controlling boundary establishment in embryo in a CUC1, CUC2 and STM-dependent manner. Involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269|PubMed:16798887}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Seems to be repressed by AS2 and AS1 but induced by STM, CUC1 and CUC2. {ECO:0000269|PubMed:11311158, ECO:0000269|PubMed:16798887}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818231e-116LN681823.1 Cucumis melo genomic scaffold, anchoredscaffold00014.
GenBankLN7132571e-116LN713257.1 Cucumis melo genomic chromosome, chr_3.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004143064.10.0PREDICTED: homeobox protein knotted-1-like 6
SwissprotQ84JS61e-120KNAT6_ARATH; Homeobox protein knotted-1-like 6
TrEMBLA0A1S3BA770.0A0A1S3BA77_CUCME; homeobox protein knotted-1-like 6
STRINGXP_004143064.10.0(Cucumis sativus)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF62034125
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G23380.11e-111KNOTTED1-like homeobox gene 6
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khan M, et al.
    Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
    Plant Physiol., 2015. 169(3): p. 2166-86
    [PMID:26417006]