PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

HD-ZIP

Protein Properties

Length: 243aa MW: 27391.8 Da PI: 7.0603

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.378700.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	62.1	8.4e-20	68	121	3	56
--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 3 kRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 k+ ++++eqle Le+ F+++ +++ +++++L+k+lgL+ rq+ vWFqNrRa++k Cucsa.378700.1 68 KKKRLSSEQLESLERSFQEEIKLDPDRKQKLSKELGLQPRQIAVWFQNRRARWK 121 45679************************************************9 PP
2	HD-ZIP_I/II	119.6	1.6e-38	67	159	1	93
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreelke 93 ekk+rls+eq+++LE+sF+ee kL+p+rK++l++eLglqprq+avWFqnrRAR+k+kqlE+ y++Lk+++da+++e+++L++ev +L++ l+e Cucsa.378700.1 67 EKKKRLSSEQLESLERSFQEEIKLDPDRKQKLSKELGLQPRQIAVWFQNRRARWKAKQLEHLYDTLKQEFDAISREKHKLQEEVMKLKSMLRE 159 69**************************************************************************************98876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	4.71E-19	57	125	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.167	63	123	IPR001356	Homeobox domain
SMART	SM00389	1.6E-17	65	127	IPR001356	Homeobox domain
Pfam	PF00046	4.1E-17	68	121	IPR001356	Homeobox domain
CDD	cd00086	6.88E-17	68	124	No hit	No description
Gene3D	G3DSA:1.10.10.60	3.7E-21	70	130	IPR009057	Homeodomain-like
PRINTS	PR00031	2.6E-5	94	103	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	98	121	IPR017970	Homeobox, conserved site
PRINTS	PR00031	2.6E-5	103	119	IPR000047	Helix-turn-helix motif
Pfam	PF02183	1.7E-8	123	157	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009965	Biological Process	leaf morphogenesis
GO:0010434	Biological Process	bract formation
GO:0010582	Biological Process	floral meristem determinacy
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0048510	Biological Process	regulation of timing of transition from vegetative to reproductive phase
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 243 aa Download sequence Send to blast
MEWATGSFRP FVSRAPESSF GFLYNYNLEQ FQVSGVDVKH SAMAGASETV LQGLVPGMDM 60 NSYGNLEKKK RLSSEQLESL ERSFQEEIKL DPDRKQKLSK ELGLQPRQIA VWFQNRRARW 120 KAKQLEHLYD TLKQEFDAIS REKHKLQEEV MKLKSMLREL QAARNQVSTV YTDLSGEETV 180 ESTSVGAGCS SKPRPVAAAA AVAAANHYTT PPEQCNYVFN TEEYNPMSPA FWGSLPSSYH 240 PQ*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	115	123	RRARWKAKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Putative transcription factor. {ECO:0000250}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00486	DAP	Transfer from AT5G03790	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KM095652	0.0	KM095652.1 Cucumis sativus multicellular trichome development class I homeodomain-leucine zipper transcription factor (Gl) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008442780.1	0.0	PREDICTED: homeobox-leucine zipper protein ATHB-22-like isoform X1
Refseq	XP_011651984.1	0.0	PREDICTED: homeobox-leucine zipper protein ATHB-22-like isoform X1
Swissprot	Q9LZR0	1e-50	ATB51_ARATH; Putative homeobox-leucine zipper protein ATHB-51
TrEMBL	A0A097A1J6	0.0	A0A097A1J6_CUCSA; Multicellular trichome development class I homeodomain-leucine zipper transcription factor
TrEMBL	A0A1S3B6J1	0.0	A0A1S3B6J1_CUCME; homeobox-leucine zipper protein ATHB-22-like isoform X1
STRING	XP_008442780.1	0.0	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF3394	34	66

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G03790.1	5e-39	homeobox 51

Link Out ? help Back to Top
Phytozome	Cucsa.378700.1
Entrez Gene	101221983

Publications ? help Back to Top
Andres RJ, et al. Modifications to a LATE MERISTEM IDENTITY1 gene are responsible for the major leaf shapes of Upland cotton (Gossypium hirsutum L.). Proc. Natl. Acad. Sci. U.S.A., 2017. 114(1): p. E57-E66 [PMID:27999177] Vuolo F, et al. LMI1 homeodomain protein regulates organ proportions by spatial modulation of endoreduplication. Genes Dev., 2018. 32(21-22): p. 1361-1366 [PMID:30366902]