PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

HSF

Protein Properties

Length: 253aa MW: 29462.8 Da PI: 9.5906

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.338180.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	109.8	2e-34	25	116	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellek 96 Fl+k+y ++ed+ ++++isw+++g++f+v+++ efa ++Lp+ Fkh+nf+SFvRQLn+YgF+k+ +++ weF +++Fkkg ke l++ Cucsa.338180.1 25 FLTKTYMLVEDPMTDDVISWNSDGTTFIVWQPPEFAIDLLPTLFKHNNFSSFVRQLNTYGFRKIATSR---------WEFYNEKFKKGCKERLCE 110 9**************************************************************999.........************** PP XXXXXX CS HSF_DNA-bind 97 ikrkks 102 i+r+k Cucsa.338180.1 111 IHRRKA 116 *985 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	4.8E-35	19	109	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	1.9E-50	21	114	IPR000232	Heat shock factor (HSF)-type, DNA-binding
SuperFamily	SSF46785	8.98E-32	22	114	IPR011991	Winged helix-turn-helix DNA-binding domain
PRINTS	PR00056	2.6E-19	25	48	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Pfam	PF00447	2.7E-30	25	114	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.6E-19	63	75	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	64	88	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.6E-19	76	88	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0046686	Biological Process	response to cadmium ion
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 253 aa Download sequence Send to blast
MVSLGNVCDQ LDSIGAVREL APSPFLTKTY MLVEDPMTDD VISWNSDGTT FIVWQPPEFA 60 IDLLPTLFKH NNFSSFVRQL NTYGFRKIAT SRWEFYNEKF KKGCKERLCE IHRRKAWTNK 120 RKHNSNAKAI QVTHQDNHDE DQRSLSTSSS DDQYTMLAYE NKKLKKENGV LSFELTNMKK 180 KCRELLDLVA KYKFVVVNGN KKKADEIMMK PNLKLFGVKL EVEEEDEMEI KQNKRKRSNY 240 PNKPFLLSQT CK*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ldu_A	1e-17	25	89	20	84	Heat shock factor protein 1
5d5u_B	1e-17	25	89	29	93	Heat shock factor protein 1
5d5v_B	1e-17	25	89	29	93	Heat shock factor protein 1
5d5v_D	1e-17	25	89	29	93	Heat shock factor protein 1
5hdg_A	8e-18	25	89	10	74	Heat shock factor protein 1
5hdn_A	8e-18	25	89	10	74	Heat shock factor protein 1
5hdn_B	8e-18	25	89	10	74	Heat shock factor protein 1
5hdn_C	8e-18	25	89	10	74	Heat shock factor protein 1
5hdn_D	8e-18	25	89	10	74	Heat shock factor protein 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00305	DAP	Transfer from AT2G41690	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681841	0.0	LN681841.1 Cucumis melo genomic scaffold, anchoredscaffold00011.
GenBank	LN713258	0.0	LN713258.1 Cucumis melo genomic chromosome, chr_4.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004136787.1	0.0	PREDICTED: heat stress transcription factor B-3-like
Swissprot	O22230	1e-63	HSFB3_ARATH; Heat stress transcription factor B-3
TrEMBL	A0A0A0LF37	0.0	A0A0A0LF37_CUCSA; Uncharacterized protein
STRING	XP_004136787.1	0.0	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1592	33	95

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G41690.1	4e-65	heat shock transcription factor B3

Link Out ? help Back to Top
Phytozome	Cucsa.338180.1
Entrez Gene	101216546

Publications ? help Back to Top
Ren Y, et al. An integrated genetic and cytogenetic map of the cucumber genome. PLoS ONE, 2009. 4(6): p. e5795 [PMID:19495411] Guo S, et al. Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics, 2010. 11: p. 384 [PMID:20565788] Li Z, et al. RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics, 2011. 12: p. 540 [PMID:22047402]