PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cucsa.312510.1
Common NameCsa_3G895630
Organism
Cucumis sativus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family HD-ZIP
Protein Properties Length: 843aa    MW: 92552.9 Da    PI: 6.0578
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cucsa.312510.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox59.36.3e-192280357
                    --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
        Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
                    k  ++t+eq+e+Le+l++++++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  Cucsa.312510.1 22 KYVRYTPEQVEALERLYYECPKPSSMRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 80
                    5679*****************************************************97 PP
2START181.64.3e-571663732204
                     HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EEEEEE CS
           START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..galqlm 94 
                     +aee+++e+++ka+ ++  Wv+++ +++g++++ +++ s++++g a+ra+g+v  +++  v+e+l+d + W ++++++++l+v+s+g  g+++l 
  Cucsa.312510.1 166 IAEETLAEFLSKATGTAVEWVQMPGMKPGPDSIGIVAISHGCTGVAARACGLVGLEPT-RVAEILKDWPSWFRDCRAVDVLNVLSTGngGTIELL 259
                     7899******************************************************.9999999999************************** PP

                     EEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHHHH CS
           START  95 vaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrslv 185
                     +++l+a+++l+p Rdf+ +Ry+  l++g++v++++S++++q+ p+    +++vRae+lpSg+li+p+++g+s +++v+h+dl+ ++++++lr+l+
  Cucsa.312510.1 260 YMQLYAPTTLAPaRDFWLLRYTSVLEDGSLVVCERSLNNTQNGPSmppVQNFVRAEMLPSGYLIRPCEGGGSIIHIVDHMDLDPWSVPEVLRPLY 354
                     *******************************************9988899********************************************* PP

                     HHHHHHHHHHHHHHTXXXX CS
           START 186 ksglaegaktwvatlqrqc 204
                     ks++  ++k+++a+l+ ++
  Cucsa.312510.1 355 KSSTLLAQKNTMAALRLLR 373
                     ***************9876 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007115.6131781IPR001356Homeobox domain
SMARTSM003893.4E-151985IPR001356Homeobox domain
SuperFamilySSF466898.55E-172184IPR009057Homeodomain-like
CDDcd000863.69E-162282No hitNo description
PfamPF000461.6E-162380IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.605.2E-182480IPR009057Homeodomain-like
CDDcd146861.30E-674113No hitNo description
PROSITE profilePS5084826156370IPR002913START domain
CDDcd088753.98E-81160375No hitNo description
SuperFamilySSF559619.48E-38165375No hitNo description
SMARTSM002341.3E-43165375IPR002913START domain
Gene3DG3DSA:3.30.530.203.2E-23165370IPR023393START-like domain
PfamPF018522.1E-54166374IPR002913START domain
PfamPF086702.1E-50701841IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010067Biological Processprocambium histogenesis
GO:0010072Biological Processprimary shoot apical meristem specification
GO:0010089Biological Processxylem development
GO:0045597Biological Processpositive regulation of cell differentiation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 843 aa     Download sequence    Send to blast
MMAVTSACKD AASKMSSLDN GKYVRYTPEQ VEALERLYYE CPKPSSMRRQ QLIRECPILS  60
NIEPKQIKVW FQNRRCREKQ RKEASRLQTV NRKLTAMNRL LMEENDRLQK QVSQLVYENS  120
YFRQQTQNAT LATTDTSCES VVTSGQQNLT PPHPPKDASP AGLLSIAEET LAEFLSKATG  180
TAVEWVQMPG MKPGPDSIGI VAISHGCTGV AARACGLVGL EPTRVAEILK DWPSWFRDCR  240
AVDVLNVLST GNGGTIELLY MQLYAPTTLA PARDFWLLRY TSVLEDGSLV VCERSLNNTQ  300
NGPSMPPVQN FVRAEMLPSG YLIRPCEGGG SIIHIVDHMD LDPWSVPEVL RPLYKSSTLL  360
AQKNTMAALR LLRQISQEVS QPNVTGWGRR PAALRALSQK LSRGFNEAVN GFTDEGWSLL  420
ENDGVDDVTL LVNMSHGKTM MGANISYSNG FPSMSNAVLC AKASMLLQNV TPAMLIRFLR  480
EHRSEWADSS IDAYSAAAIK TGQCGLPGSH AGTFGGQVIL PLAQTVEHEE FMEVVKFENV  540
GHYRDDMLMP GDIFLLQLCN GVDENTVGTS AELIFAPIDA SFSDDAPILP SGFRIIPLDS  600
GMDASSPNRT LDLASALDVG PAGNRASGDC AGQSGKSKSV MTIAFQFVFD VHLQDNVAAM  660
ARQYVRSIIA SVQRVALALS PSNFGPHANL QTPAGAPEAQ TLARWITQSY RCYMGMELLK  720
NEGRESVLKS LWHHSDAVMC CSLKALPNFT FANQSGLDML ETTLVALQDI TLEKIFDDNG  780
KKTLASEFPR IMQQGFICLQ GGVCLSSMGR AVSYEKAVAW KVLNEEENAH CICFMFMNWS  840
FV*
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of vascular development. May promote differentiation of precambial and cambial cells. {ECO:0000269|PubMed:11402194, ECO:0000269|PubMed:15598805}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by miR165. {ECO:0000269|PubMed:17237362, ECO:0000269|PubMed:8575317}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004136224.10.0PREDICTED: homeobox-leucine zipper protein ATHB-8
SwissprotQ391230.0ATHB8_ARATH; Homeobox-leucine zipper protein ATHB-8
TrEMBLA0A0A0LHU60.0A0A0A0LHU6_CUCSA; Uncharacterized protein
STRINGXP_004136224.10.0(Cucumis sativus)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19463387
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G32880.10.0homeobox gene 8
Publications ? help Back to Top
  1. Ren Y, et al.
    An integrated genetic and cytogenetic map of the cucumber genome.
    PLoS ONE, 2009. 4(6): p. e5795
    [PMID:19495411]
  2. Guo S, et al.
    Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types.
    BMC Genomics, 2010. 11: p. 384
    [PMID:20565788]
  3. Li Z, et al.
    RNA-Seq improves annotation of protein-coding genes in the cucumber genome.
    BMC Genomics, 2011. 12: p. 540
    [PMID:22047402]
  4. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  5. Hategan L,Godza B,Kozma-Bognar L,Bishop GJ,Szekeres M
    Differential expression of the brassinosteroid receptor-encoding BRI1 gene in Arabidopsis.
    Planta, 2014. 239(5): p. 989-1001
    [PMID:24488524]
  6. Baima S, et al.
    Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module.
    Mol Plant, 2014. 7(6): p. 1006-1025
    [PMID:24777988]
  7. Kakehi J, et al.
    Mutations in ribosomal proteins, RPL4 and RACK1, suppress the phenotype of a thermospermine-deficient mutant of Arabidopsis thaliana.
    PLoS ONE, 2015. 10(1): p. e0117309
    [PMID:25625317]
  8. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  9. Liu S, et al.
    Expression of wild-type PtrIAA14.1, a poplar Aux/IAA gene causes morphological changes in Arabidopsis.
    Front Plant Sci, 2015. 6: p. 388
    [PMID:26082787]
  10. Yamaguchi YL, et al.
    Root-Knot and Cyst Nematodes Activate Procambium-Associated Genes in Arabidopsis Roots.
    Front Plant Sci, 2017. 8: p. 1195
    [PMID:28747918]
  11. Yamazaki K, et al.
    Suppression of DELLA signaling induces procambial cell formation in culture.
    Plant J., 2018. 94(1): p. 48-59
    [PMID:29383774]