PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

HD-ZIP

Protein Properties

Length: 299aa MW: 34023.8 Da PI: 6.7999

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.285250.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	56	6.9e-18	86	139	3	56
--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 3 kRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 k+++++ eq+++Le+ Fe +++ e++ +LA+ lgL+ rq+ +WFqNrRa++k Cucsa.285250.1 86 KKRRLNMEQVKTLEKNFELGNKLEPERKMQLARALGLQPRQIAIWFQNRRARWK 139 456899***********************************************9 PP
2	HD-ZIP_I/II	130.2	8.4e-42	85	177	1	93
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreelke 93 ekkrrl+ eqvk+LE++Fe +kLeperK++lar+Lglqprq+a+WFqnrRAR+ktkqlEkdy+ Lkr+++a+k++ne+L++++++L++e+++ Cucsa.285250.1 85 EKKRRLNMEQVKTLEKNFELGNKLEPERKMQLARALGLQPRQIAIWFQNRRARWKTKQLEKDYDLLKRQFEAIKSDNEALKSHNQKLQAEIMA 177 69**************************************************************************************99975 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	1.8E-19	75	143	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.329	81	141	IPR001356	Homeobox domain
SMART	SM00389	1.8E-17	84	145	IPR001356	Homeobox domain
Pfam	PF00046	3.0E-15	86	139	IPR001356	Homeobox domain
CDD	cd00086	1.40E-15	86	142	No hit	No description
Gene3D	G3DSA:1.10.10.60	5.1E-19	88	148	IPR009057	Homeodomain-like
PRINTS	PR00031	1.2E-5	112	121	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	116	139	IPR017970	Homeobox, conserved site
PRINTS	PR00031	1.2E-5	121	137	IPR000047	Helix-turn-helix motif
Pfam	PF02183	1.8E-16	141	181	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009744	Biological Process	response to sucrose
GO:0048826	Biological Process	cotyledon morphogenesis
GO:0080022	Biological Process	primary root development
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 299 aa Download sequence Send to blast
MTSNGMAFFP ANFMLQPSHE DHDHHHHSNS PPSLNPILPS CTPQDFHGVA SFLGKRSMSF 60 SGTEMVEEGN NGEDEFSDDG SQAGEKKRRL NMEQVKTLEK NFELGNKLEP ERKMQLARAL 120 GLQPRQIAIW FQNRRARWKT KQLEKDYDLL KRQFEAIKSD NEALKSHNQK LQAEIMALKS 180 REPTESINLN KETEGSCSNR SENSSDNIKL DISRTPAIDS PHQQHPTNRP LFPTSSSLRP 240 PALAQLFQTS SRSSDHPPKQ IDNHHQIPKE ESSSLSNMFC GMDDHSGFWP WLEQQHFN*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	133	141	RRARWKTKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor that may act in the sucrose-signaling pathway. {ECO:0000269\|PubMed:11292072}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00225	DAP	Transfer from AT1G69780	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681896	0.0	LN681896.1 Cucumis melo genomic scaffold, anchoredscaffold00016.
GenBank	LN713264	0.0	LN713264.1 Cucumis melo genomic chromosome, chr_10.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004135187.1	0.0	PREDICTED: homeobox-leucine zipper protein ATHB-13
Swissprot	Q8LC03	1e-127	ATB13_ARATH; Homeobox-leucine zipper protein ATHB-13
TrEMBL	A0A0A0KQK4	0.0	A0A0A0KQK4_CUCSA; Uncharacterized protein
STRING	XP_004135187.1	0.0	(Cucumis sativus)
STRING	XP_004155316.1	0.0	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1271	33	106

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G69780.1	1e-117	HD-ZIP family protein

Link Out ? help Back to Top
Phytozome	Cucsa.285250.1
Entrez Gene	101221595

Publications ? help Back to Top
Ren Y, et al. An integrated genetic and cytogenetic map of the cucumber genome. PLoS ONE, 2009. 4(6): p. e5795 [PMID:19495411] Guo S, et al. Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics, 2010. 11: p. 384 [PMID:20565788] Li Z, et al. RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics, 2011. 12: p. 540 [PMID:22047402] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Ribone PA,Capella M,Chan RL Functional characterization of the homeodomain leucine zipper I transcription factor AtHB13 reveals a crucial role in Arabidopsis development. J. Exp. Bot., 2015. 66(19): p. 5929-43 [PMID:26136262] Wang X, et al. Overexpressed BRH1, a RING finger gene, alters rosette leaf shape in Arabidopsis thaliana. Sci China Life Sci, 2018. 61(1): p. 79-87 [PMID:28887625] Ebrahimian-Motlagh S, et al. JUNGBRUNNEN1 Confers Drought Tolerance Downstream of the HD-Zip I Transcription Factor AtHB13. Front Plant Sci, 2017. 8: p. 2118 [PMID:29326734]