PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cucsa.280790.1
Common NameCsa_5G577350, Gl-3, LOC105435546
Organism
Cucumis sativus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family C2H2
Protein Properties Length: 214aa    MW: 22730.1 Da    PI: 6.877
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cucsa.280790.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H213.40.000235779123
                    EEETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2  1 ykCpdCgksFsrksnLkrHirtH 23
                    y+C++C + F ++  L  H++ H
  Cucsa.280790.1 57 YECQYCYREFANSQALGGHQNAH 79
                    99******************988 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.603.0E-55283IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576671.15E-65384No hitNo description
PROSITE profilePS5015711.6765784IPR007087Zinc finger, C2H2
PfamPF139121.0E-55781IPR007087Zinc finger, C2H2
PROSITE patternPS0002805979IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009736Biological Processcytokinin-activated signaling pathway
GO:0009740Biological Processgibberellic acid mediated signaling pathway
GO:0010090Biological Processtrichome morphogenesis
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 214 aa     Download sequence    Send to blast
MAALENHYQT KQNNNNPATT RLKLFGFDVQ EDLDQDDSTP TSSDSGAAVP SSGDRKYECQ  60
YCYREFANSQ ALGGHQNAHK KERQQLKRAQ LQASRNAAVF RNPIVAAFAP PPHLLPSAAV  120
TASSSWPVYI PRAPPQFQVS HGCVFTPSSS YGGGGDAPPP PSPPDFFTMG SRSSHGMVDA  180
PMSLSRFSKV DGGTAFDDGP GLDLHLSLAP AAP*
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor required for the initiation of inflorescence trichomes in response to gibberellin and cytokinin. Acts upstream of GIS, GIS2, ZFP8, and the trichome initiation factors GL1 and GL3. Binds the promoter region of GIS and GIS2, which may be direct targets of GIS3. {ECO:0000269|PubMed:25640859}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKM0956540.0KM095654.1 Cucumis sativus multicellular trichome development C2H2 zinc finger transcription factor (Gl-3) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001295848.11e-156zinc finger protein 6-like
SwissprotQ9C9H12e-50GIS3_ARATH; Zinc finger protein GIS3
TrEMBLA0A0A0KRQ51e-155A0A0A0KRQ5_CUCSA; Multicellular trichome development C2H2 zinc finger transcription factor
STRINGXP_004171266.11e-156(Cucumis sativus)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF31981316
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G06650.11e-14C2H2 family protein
Publications ? help Back to Top
  1. Ren Y, et al.
    An integrated genetic and cytogenetic map of the cucumber genome.
    PLoS ONE, 2009. 4(6): p. e5795
    [PMID:19495411]
  2. Guo S, et al.
    Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types.
    BMC Genomics, 2010. 11: p. 384
    [PMID:20565788]
  3. Li Z, et al.
    RNA-Seq improves annotation of protein-coding genes in the cucumber genome.
    BMC Genomics, 2011. 12: p. 540
    [PMID:22047402]
  4. Sun L, et al.
    GLABROUS INFLORESCENCE STEMS3 (GIS3) regulates trichome initiation and development in Arabidopsis.
    New Phytol., 2015. 206(1): p. 220-30
    [PMID:25640859]