PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cucsa.273280.1

Common Name

Csa_4G091920, LOC101208690

Organism

Cucumis sativus

Taxonomic ID

3659

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

NAC

Protein Properties

Length: 432aa MW: 48364.6 Da PI: 4.4826

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.273280.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	169.7	9.2e-53	9	136	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp..kkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevl 93 lp GfrF+Ptdeel+++yL+ k++g++ ++ +vi+evd++k+ePwdLp + +k+++ ew+fF+++d+ky++g+r +rat +gyWkatgkd++++ Cucsa.273280.1 9 LPLGFRFRPTDEELIDYYLRSKINGNHEDV-SVIREVDVCKWEPWDLPdlSIIKTKDPEWFFFCPQDRKYPNGHRLKRATVAGYWKATGKDRKIK 102 699**********************999.99**********96447788889*********************************** PP NAM 94 skkgelvglkktLvfykgrapkgektdWvmheyrl 128 s +++l+g+kktLvfykgrapkg++t+Wv+heyr+ Cucsa.273280.1 103 S-GTKLIGMKKTLVFYKGRAPKGKRTNWVVHEYRA 136 .99****************************96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	1.15E-59	4	159	IPR003441	NAC domain
PROSITE profile	PS51005	56.11	9	159	IPR003441	NAC domain
Pfam	PF02365	2.3E-26	10	135	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0002230	Biological Process	positive regulation of defense response to virus by host
GO:0002237	Biological Process	response to molecule of bacterial origin
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0016021	Cellular Component	integral component of membrane
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0003713	Molecular Function	transcription coactivator activity
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 432 aa Download sequence Send to blast
MAVLTLNSLP LGFRFRPTDE ELIDYYLRSK INGNHEDVSV IREVDVCKWE PWDLPDLSII 60 KTKDPEWFFF CPQDRKYPNG HRLKRATVAG YWKATGKDRK IKSGTKLIGM KKTLVFYKGR 120 APKGKRTNWV VHEYRATLKE LDGTNPGQSA FVLCRLFKKQ DESIEGSNGD EAEAAISSPT 180 TAESSPGPGD SHSEPILPLV SPSLQRQAES SDGVLSETVE HTDGSADIHG FDSYNAEMDT 240 HPDEERKFCG SENKPLDSKL YSPLHSQLQA ELGSSGIYYS DSNYLNYEAN GNAEQLPSGT 300 EESDFINQML DSFVYNLDDF PLEDQQEFMS LSEFPNNTMD SLDNGFFGKV EADNVKAMVM 360 PDFESSICLE DIDRKTPIID HVGTSPPEQG QFYNISGSLQ ESYNQSSAVE VWMLELEFRE 420 SVASKKSTTA K*

Sequence ? help Back to Top

Protein Sequence Length: 432 aa Download sequence Send to blast

MAVLTLNSLP LGFRFRPTDE ELIDYYLRSK INGNHEDVSV IREVDVCKWE PWDLPDLSII  60
KTKDPEWFFF CPQDRKYPNG HRLKRATVAG YWKATGKDRK IKSGTKLIGM KKTLVFYKGR  120
APKGKRTNWV VHEYRATLKE LDGTNPGQSA FVLCRLFKKQ DESIEGSNGD EAEAAISSPT  180
TAESSPGPGD SHSEPILPLV SPSLQRQAES SDGVLSETVE HTDGSADIHG FDSYNAEMDT  240
HPDEERKFCG SENKPLDSKL YSPLHSQLQA ELGSSGIYYS DSNYLNYEAN GNAEQLPSGT  300
EESDFINQML DSFVYNLDDF PLEDQQEFMS LSEFPNNTMD SLDNGFFGKV EADNVKAMVM  360
PDFESSICLE DIDRKTPIID HVGTSPPEQG QFYNISGSLQ ESYNQSSAVE VWMLELEFRE  420
SVASKKSTTA K*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	7e-45	4	163	12	169	NO APICAL MERISTEM PROTEIN
1ut4_B	7e-45	4	163	12	169	NO APICAL MERISTEM PROTEIN
1ut7_A	7e-45	4	163	12	169	NO APICAL MERISTEM PROTEIN
1ut7_B	7e-45	4	163	12	169	NO APICAL MERISTEM PROTEIN
3swm_A	9e-45	4	163	15	172	NAC domain-containing protein 19
3swm_B	9e-45	4	163	15	172	NAC domain-containing protein 19
3swm_C	9e-45	4	163	15	172	NAC domain-containing protein 19
3swm_D	9e-45	4	163	15	172	NAC domain-containing protein 19
3swp_A	9e-45	4	163	15	172	NAC domain-containing protein 19
3swp_B	9e-45	4	163	15	172	NAC domain-containing protein 19
3swp_C	9e-45	4	163	15	172	NAC domain-containing protein 19
3swp_D	9e-45	4	163	15	172	NAC domain-containing protein 19
4dul_A	7e-45	4	163	12	169	NAC domain-containing protein 19
4dul_B	7e-45	4	163	12	169	NAC domain-containing protein 19
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator essential for the anti-viral defense called virus basal resistance response pathway (PubMed:11041886, PubMed:15629774, PubMed:18785827, PubMed:24418554). Not involved in HRT-mediated hypersensitive response (HR) and resistance to TCV (PubMed:18785827). Binds DNA non specifically (PubMed:15629774). Activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (By similarity). {ECO:0000250\|UniProtKB:Q9SCK6, ECO:0000269\|PubMed:11041886, ECO:0000269\|PubMed:15629774, ECO:0000269\|PubMed:18785827, ECO:0000269\|PubMed:24418554}.; FUNCTION: (Microbial infection) Compromised function in defense response pathway when interacting with the invading viral capsid protein (CP) of turnip crinkle virus (TCV) due to abnormal subcellular localization. {ECO:0000269\|PubMed:11041886, ECO:0000269\|PubMed:15629774}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by bacterial pathogens type III effector proteins (TTEs). {ECO:0000269\|PubMed:16553893}.; INDUCTION: (Microbial infection) Accumulates 2 days post infection with turnip crinkle virus (TCV) (PubMed:24418554). {ECO:0000269\|PubMed:24418554}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011653333.1	0.0	PREDICTED: NAC domain-containing protein 74
Swissprot	Q9LKG8	2e-97	NAC91_ARATH; NAC domain-containing protein 91
TrEMBL	A0A0A0L0H2	0.0	A0A0A0L0H2_CUCSA; Uncharacterized protein
STRING	XP_004156529.1	0.0	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF5551	33	53

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G24590.2	1e-100	TCV-interacting protein

Link Out ? help Back to Top
Phytozome	Cucsa.273280.1
Entrez Gene	101208690

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ren Y, et al. An integrated genetic and cytogenetic map of the cucumber genome. PLoS ONE, 2009. 4(6): p. e5795 [PMID:19495411] Guo S, et al. Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics, 2010. 11: p. 384 [PMID:20565788] Li Z, et al. RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics, 2011. 12: p. 540 [PMID:22047402] Ben Daniel BH, et al. Identification of novel transcriptional regulators of Zat12 using comprehensive yeast one-hybrid screens. Physiol Plant, 2016. 157(4): p. 422-41 [PMID:26923089] Li Y, et al. The interaction between Turnip crinkle virus p38 and Cucumber mosaic virus 2b and its critical domains. Virus Res., 2016. 222: p. 94-105 [PMID:27288723]