PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cucsa.259300.1
Common NameCsa_3G119500
Organism
Cucumis sativus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family bHLH
Protein Properties Length: 620aa    MW: 68551.9 Da    PI: 5.9419
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cucsa.259300.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH40.45.1e-13448494455
                     HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
             HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                     +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI++Lq
  Cucsa.259300.1 448 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYINELQ 494
                     799***********************66......******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142159.5E-5552240IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088817.047444493IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.34E-14447498No hitNo description
SuperFamilySSF474593.53E-18447507IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.107.2E-18448506IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.8E-10448494IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003538.4E-17450499IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 620 aa     Download sequence    Send to blast
MKIEDGLRSV GGKDEDKTVV AAVLGTRAFN YLMSCSVSNE NLFMAVRNDE NLQNKLSDLV  60
ERPNASNFSW NYAIFWQLSH SKSGEWVLGW GDGSCRDPRD GDETEATQIL SLQLEDESQQ  120
RMKKRALQKL HTLFGGSDED NYALGLDRVT DTEMFFLASM YFSFPRGEGG PGKCLASGKH  180
IWNLDVLNSP SEYCVRSYLA KSAGIQTVVL VPTDVGVVEL GSVRSVNESL ELVQLIRSLF  240
SSQLSLDRVR SSAAMSMIAE RKDESTSFAS WGIAERGEGG GGIPKVFGQT LNSGNMGRSH  300
FREKLAIRKM DERSWEACAN GGRIQFQSPR NGIRSPSLAH VHGLKQGNHS PAEIYVSPTP  360
PVNNNHEQLV SGVRDEFGLN PYQSQKLAQM QIDFSVATSR PSVINRVGAD SEHSDVEPQC  420
KEEGPGTDER RPRKRGRKPA NGREEPLNHV EAERQRREKL NQRFYALRAV VPNISKMDKA  480
SLLGDAIAYI NELQEKVKVM EFEREKSSLT SSEATPSEGN PEIETKDQFL DVDIDVEAAH  540
DEVIVKVSCP LESHPASRVI KAMRDAQINV IDSKLSEAND KVLHTFVIKS PGSEQLTKEK  600
LIAAFSQDST SLHPLPTVG*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A4e-29442504264Transcription factor MYC2
5gnj_B4e-29442504264Transcription factor MYC2
5gnj_E4e-29442504264Transcription factor MYC2
5gnj_F4e-29442504264Transcription factor MYC2
5gnj_G4e-29442504264Transcription factor MYC2
5gnj_I4e-29442504264Transcription factor MYC2
5gnj_M4e-29442504264Transcription factor MYC2
5gnj_N4e-29442504264Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1429437RRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00100PBMTransfer from AT1G01260Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818480.0LN681848.1 Cucumis melo genomic scaffold, anchoredscaffold00006.
GenBankLN7132600.0LN713260.1 Cucumis melo genomic chromosome, chr_6.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004133809.10.0PREDICTED: transcription factor bHLH13
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A1S3AV620.0A0A1S3AV62_CUCME; LOW QUALITY PROTEIN: transcription factor bHLH13
STRINGXP_004172828.10.0(Cucumis sativus)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF54483254
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01260.30.0bHLH family protein
Publications ? help Back to Top
  1. Ren Y, et al.
    An integrated genetic and cytogenetic map of the cucumber genome.
    PLoS ONE, 2009. 4(6): p. e5795
    [PMID:19495411]
  2. Guo S, et al.
    Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types.
    BMC Genomics, 2010. 11: p. 384
    [PMID:20565788]
  3. Li Z, et al.
    RNA-Seq improves annotation of protein-coding genes in the cucumber genome.
    BMC Genomics, 2011. 12: p. 540
    [PMID:22047402]
  4. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  5. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  6. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]