PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

ERF

Protein Properties

Length: 213aa MW: 24039.7 Da PI: 7.1476

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.258900.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	62.8	7.5e-20	77	126	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 +++GVr+++ +g+W+AeIrdp r +r++lg+++taeeAa +++a+ +l+g Cucsa.258900.1 77 KFRGVRRRP-WGKWAAEIRDPL----RrTRVWLGTYDTAEEAAVVYDQAAVRLRG 126 89*****.******73....45***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PIRSF	PIRSF038123	4.0E-49	1	189	IPR017392	AP2/ERF transcription factor ERF/PTI6
Gene3D	G3DSA:3.30.730.10	3.2E-30	76	134	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	23.446	77	134	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	5.89E-22	77	134	IPR016177	DNA-binding domain
CDD	cd00018	8.03E-30	77	133	No hit	No description
SMART	SM00380	3.4E-37	77	140	IPR001471	AP2/ERF domain
Pfam	PF00847	1.3E-12	77	126	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.1E-10	78	89	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.1E-10	100	116	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 213 aa Download sequence Send to blast
ETRTVTHKPA AETKLVRISY TDADATDSSS GEDEEPILVR HVKRHVTEIR LLTTDCSKKA 60 PPKSRANPPR NSESHRKFRG VRRRPWGKWA AEIRDPLRRT RVWLGTYDTA EEAAVVYDQA 120 AVRLRGPSAL TNFVAETPHS ETTLVTYLTP PPPENQSAAA AVSETKESRS ICSPTSVLRL 180 EDENWRAIDH YLSEESGLED EFNWLYDRNS NK*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	3e-21	75	139	12	73	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Component of the cytokinin signaling pathway involved in cotyledons, leaves, and embryos development. Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269\|PubMed:16832061}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681848	0.0	LN681848.1 Cucumis melo genomic scaffold, anchoredscaffold00006.
GenBank	LN713260	0.0	LN713260.1 Cucumis melo genomic chromosome, chr_6.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004133833.2	1e-152	PREDICTED: pathogenesis-related genes transcriptional activator PTI6-like
Swissprot	Q9SUE3	2e-40	CRF4_ARATH; Ethylene-responsive transcription factor CRF4
TrEMBL	A0A0A0L397	1e-150	A0A0A0L397_CUCSA; Uncharacterized protein
STRING	XP_004133833.1	1e-151	(Cucumis sativus)
STRING	XP_004155156.1	1e-151	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF450	34	161

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G27950.1	4e-35	cytokinin response factor 4

Link Out ? help Back to Top
Phytozome	Cucsa.258900.1
Entrez Gene	101214687

Publications ? help Back to Top
Ren Y, et al. An integrated genetic and cytogenetic map of the cucumber genome. PLoS ONE, 2009. 4(6): p. e5795 [PMID:19495411] Guo S, et al. Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics, 2010. 11: p. 384 [PMID:20565788] Li Z, et al. RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics, 2011. 12: p. 540 [PMID:22047402] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zwack PJ,Compton MA,Adams CI,Rashotte AM Cytokinin response factor 4 (CRF4) is induced by cold and involved in freezing tolerance. Plant Cell Rep., 2016. 35(3): p. 573-84 [PMID:26650835] Raines T, et al. The cytokinin response factors modulate root and shoot growth and promote leaf senescence in Arabidopsis. Plant J., 2016. 85(1): p. 134-47 [PMID:26662515]