PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

ZF-HD

Protein Properties

Length: 308aa MW: 33148.9 Da PI: 7.1533

Description

ZF-HD family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.232110.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	ZF-HD_dimer	102.9	2.2e-32	78	134	3	60
ZF-HD_dimer 3 kvrYkeClkNhAaslGghavDGCgEfmpsegeegtaaalkCaACgCHRnFHRreveee 60 +vrY+eClkNhAas+Gg+ +DGCgEfmps ge+gt +alkCaAC+CHRnFHR+e + e Cucsa.232110.1 78 GVRYRECLKNHAASVGGNIYDGCGEFMPS-GEDGTLEALKCAACECHRNFHRKEIDGE 134 79************************9.999******************98865 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF04770	7.5E-30	79	131	IPR006456	ZF-HD homeobox protein, Cys/His-rich dimerisation domain
TIGRFAMs	TIGR01566	1.6E-30	80	131	IPR006456	ZF-HD homeobox protein, Cys/His-rich dimerisation domain
PROSITE profile	PS51523	26.487	81	130	IPR006456	ZF-HD homeobox protein, Cys/His-rich dimerisation domain
ProDom	PD125774	3.0E-22	81	132	IPR006456	ZF-HD homeobox protein, Cys/His-rich dimerisation domain
Gene3D	G3DSA:1.10.10.60	2.4E-31	214	286	IPR009057	Homeodomain-like
SuperFamily	SSF46689	2.41E-20	216	286	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01565	2.0E-28	224	281	IPR006455	Homeodomain, ZF-HD class

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009737	Biological Process	response to abscisic acid
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0042803	Molecular Function	protein homodimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 308 aa Download sequence Send to blast
MDMREQEKEV IMPGANSGAA AYGHIFGETS SERIHNGSHH HIQTDHHDAG GGGGGGGGGG 60 GGNFSAGGRS KVRGGVSGVR YRECLKNHAA SVGGNIYDGC GEFMPSGEDG TLEALKCAAC 120 ECHRNFHRKE IDGETQLNIS PNYRRGLMLN HLQLPPPLPS PSALHGHHKF SMALNLHSSP 180 TAPIIAPMNV AFAGGGGNES SSEDLNVFHS NAEVMPPSSF SLSKKRFRTK FTQEQKDRML 240 EFAEKVGWRI QKQDEEEVER FCTEVGVKRQ VLKVWMHNNK NTVKKQNENH EPELAGTGAG 300 AGITNES*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wh7_A	4e-25	223	282	16	75	ZF-HD homeobox family protein
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Putative transcription factor. Binds DNA at 5'-ATTA-3' consensus promoter regions. Regulates floral architecture and leaf development. Regulators in the abscisic acid (ABA) signal pathway that confers sensitivity to ABA in an ARF2-dependent manner. {ECO:0000269\|PubMed:16428600, ECO:0000269\|PubMed:21059647, ECO:0000269\|PubMed:21779177}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00238	DAP	Transfer from AT1G75240	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by abscisic acid (ABA) and ARF2. {ECO:0000269\|PubMed:21779177}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681823	0.0	LN681823.1 Cucumis melo genomic scaffold, anchoredscaffold00014.
GenBank	LN713257	0.0	LN713257.1 Cucumis melo genomic chromosome, chr_3.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011649626.1	0.0	PREDICTED: zinc-finger homeodomain protein 5
Swissprot	Q9FRL5	1e-66	ZHD5_ARATH; Zinc-finger homeodomain protein 5
TrEMBL	A0A0A0LRH9	0.0	A0A0A0LRH9_CUCSA; Uncharacterized protein
STRING	XP_004165400.1	0.0	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF206	34	253

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G18350.1	1e-61	homeobox protein 24

Link Out ? help Back to Top
Phytozome	Cucsa.232110.1
Entrez Gene	101216040

Publications ? help Back to Top
Ren Y, et al. An integrated genetic and cytogenetic map of the cucumber genome. PLoS ONE, 2009. 4(6): p. e5795 [PMID:19495411] Guo S, et al. Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics, 2010. 11: p. 384 [PMID:20565788] Li Z, et al. RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics, 2011. 12: p. 540 [PMID:22047402]