PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cucsa.222420.1

Organism

Cucumis sativus

Taxonomic ID

3659

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

C2H2

Protein Properties

Length: 424aa MW: 46896.2 Da PI: 9.4801

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.222420.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	16.9	1.7e-05	60	82	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H Cucsa.222420.1 60 FVCEICSKGFQRDQNLQLHRRGH 82 89*******************88 PP
2	zf-C2H2	12.1	0.00058	136	158	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC++C+k + +s+ k H + + Cucsa.222420.1 136 WKCEKCSKKYAVQSDWKAHSKIC 158 58*****************9876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	4.8E-7	59	82	No hit	No description
Gene3D	G3DSA:3.30.160.60	5.7E-5	59	82	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.036	60	82	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.887	60	82	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	62	82	IPR007087	Zinc finger, C2H2
SMART	SM00355	84	101	131	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	4.8E-5	124	157	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	4.8E-7	131	156	No hit	No description
SMART	SM00355	140	136	156	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 424 aa Download sequence Send to blast
MMSEFVSTMS NLIGEEQHQY HNSNPVLVPL KKKRNLPGTP DPDAEVIAMS PKSLMAKNRF 60 VCEICSKGFQ RDQNLQLHRR GHNLPWKLRQ RTNKEVRKKV YVCPEKSCVH HDPARALGDL 120 TGIKKHYSRK HGEKKWKCEK CSKKYAVQSD WKAHSKICGT KEYKCDCGTL FSRKDSFITH 180 RAFCDALAEE NSRINHHPTF INNNFSPTSS SLLLQQPNFP PSSATATATA TTTTVIDQSP 240 LAHHFPNIIF DHDDDHKPRP LSISSPPQLP LWLDPPPNPN SFFSAAPAIH TFSENPTFFP 300 ENQYPFLSEA LTTASSYTVA PHMSATALLQ KAAQMGPTVT PTISPILFNA PTATTGRGYG 360 MINSTAAVVG LSDGRSTMKP LMGGAKEEIG GHNLTRDFLG VGNQVVHLTP VGSNQYGDQS 420 RRN*

Sequence ? help Back to Top

Protein Sequence Length: 424 aa Download sequence Send to blast

MMSEFVSTMS NLIGEEQHQY HNSNPVLVPL KKKRNLPGTP DPDAEVIAMS PKSLMAKNRF  60
VCEICSKGFQ RDQNLQLHRR GHNLPWKLRQ RTNKEVRKKV YVCPEKSCVH HDPARALGDL  120
TGIKKHYSRK HGEKKWKCEK CSKKYAVQSD WKAHSKICGT KEYKCDCGTL FSRKDSFITH  180
RAFCDALAEE NSRINHHPTF INNNFSPTSS SLLLQQPNFP PSSATATATA TTTTVIDQSP  240
LAHHFPNIIF DHDDDHKPRP LSISSPPQLP LWLDPPPNPN SFFSAAPAIH TFSENPTFFP  300
ENQYPFLSEA LTTASSYTVA PHMSATALLQ KAAQMGPTVT PTISPILFNA PTATTGRGYG  360
MINSTAAVVG LSDGRSTMKP LMGGAKEEIG GHNLTRDFLG VGNQVVHLTP VGSNQYGDQS  420
RRN*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	2e-36	132	204	3	72	Zinc finger protein JACKDAW
5b3h_F	2e-36	132	204	3	72	Zinc finger protein JACKDAW
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	86	98	KLRQRTNKEVRKK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681928	0.0	LN681928.1 Cucumis melo genomic scaffold, anchoredscaffold00004.
GenBank	LN713266	0.0	LN713266.1 Cucumis melo genomic chromosome, chr_12.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004148767.1	0.0	PREDICTED: protein indeterminate-domain 2
Swissprot	Q9SCQ6	1e-120	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A0A0LSI1	0.0	A0A0A0LSI1_CUCSA; Uncharacterized protein
STRING	XP_004148767.1	0.0	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF181	34	275

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	1e-107	indeterminate(ID)-domain 2

Link Out ? help Back to Top
Phytozome	Cucsa.222420.1

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]