PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

HD-ZIP

Protein Properties

Length: 208aa MW: 24174.1 Da PI: 7.6599

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.201240.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	62.3	7.5e-20	57	111	3	57
--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHHC CS Homeobox 3 kRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakekk 57 k++++t+ q++ Le+ F +++++ e++ +LA++lgL+ rqV vWFqNrRa++k+ Cucsa.201240.1 57 KKRKLTAAQVRLLESNFGSEHKLESERKDRLASELGLDPRQVAVWFQNRRARWKN 111 45689************************************************95 PP
2	HD-ZIP_I/II	117.2	9e-38	57	147	2	92
HD-ZIP_I/II 2 kkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreelk 92 kkr+l++ qv+lLE++F +e+kLe+erK +la+eLgl+prqvavWFqnrRAR+k+k+lE++y+ Lk+ +++++ e++rLe+e +L+e+l Cucsa.201240.1 57 KKRKLTAAQVRLLESNFGSEHKLESERKDRLASELGLDPRQVAVWFQNRRARWKNKKLEEEYSNLKKLHESVVVEKCRLETELLKLKEQLL 147 9**************************************************************************************9986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50071	16.746	52	112	IPR001356	Homeobox domain
SMART	SM00389	2.9E-18	55	116	IPR001356	Homeobox domain
SuperFamily	SSF46689	2.22E-18	56	120	IPR009057	Homeodomain-like
CDD	cd00086	1.15E-14	57	113	No hit	No description
Pfam	PF00046	3.5E-17	57	111	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	5.5E-21	59	119	IPR009057	Homeodomain-like
PRINTS	PR00031	1.3E-5	83	92	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	87	110	IPR017970	Homeobox, conserved site
PRINTS	PR00031	1.3E-5	92	108	IPR000047	Helix-turn-helix motif

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 208 aa Download sequence Send to blast
MNQQQTDQEH QSVQISQLYN GLYIQMLPQQ VHLGESKPRR RRKKNRGSET EAASGGKKRK 60 LTAAQVRLLE SNFGSEHKLE SERKDRLASE LGLDPRQVAV WFQNRRARWK NKKLEEEYSN 120 LKKLHESVVV EKCRLETELL KLKEQLLEVE KEKERVRMGE GGDGPLSSSS PSPSMSMEAM 180 EMEQPISLGE ISPLYEEDVF YYMPENYX

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	41	59	RKKNRGSETEAASGGKKRK

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000250}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By abscisic acid (ABA) and by salt stress. {ECO:0000269\|PubMed:16055682}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681874	1e-153	LN681874.1 Cucumis melo genomic scaffold, anchoredscaffold00031.
GenBank	LN713261	1e-153	LN713261.1 Cucumis melo genomic chromosome, chr_7.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004146482.1	1e-149	PREDICTED: homeobox-leucine zipper protein ATHB-40-like
Swissprot	Q9ZU70	1e-58	ATB21_ARATH; Homeobox-leucine zipper protein ATHB-21
TrEMBL	A0A0A0KWL3	1e-147	A0A0A0KWL3_CUCSA; Uncharacterized protein
STRING	XP_004146482.1	1e-148	(Cucumis sativus)
STRING	XP_004172400.1	1e-148	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF4789	32	57

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G36740.1	1e-45	homeobox protein 40

Link Out ? help Back to Top
Phytozome	Cucsa.201240.1
Entrez Gene	101221080

Publications ? help Back to Top
Ren Y, et al. An integrated genetic and cytogenetic map of the cucumber genome. PLoS ONE, 2009. 4(6): p. e5795 [PMID:19495411] Guo S, et al. Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics, 2010. 11: p. 384 [PMID:20565788] Li Z, et al. RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics, 2011. 12: p. 540 [PMID:22047402] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] González-Grandío E, et al. Abscisic acid signaling is controlled by a BRANCHED1/HD-ZIP I cascade in Arabidopsis axillary buds. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(2): p. E245-E254 [PMID:28028241]