PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cucsa.135510.1

Organism

Cucumis sativus

Taxonomic ID

3659

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

bHLH

Protein Properties

Length: 645aa MW: 72769.5 Da PI: 5.4691

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.135510.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	19.1	2.4e-06	458	491	17	55
HHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 17 NsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 N++f L+++lP++ +K++iL +++Y+k+L+ Cucsa.135510.1 458 NEKFMALKSMLPSL-----NEINKVSILNDTIKYLKMLE 491 99*********8.....58*************995 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF14215	1.3E-52	8	189	IPR025610	Transcription factor MYC/MYB N-terminal
PROSITE profile	PS50888	9.026	441	490	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.5E-4	450	496	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	2.96E-6	456	495	No hit	No description
Gene3D	G3DSA:4.10.280.10	4.6E-9	458	504	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.44E-9	458	512	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009957	Biological Process	epidermal cell fate specification
GO:0010091	Biological Process	trichome branching
GO:0005634	Cellular Component	nucleus
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 645 aa Download sequence Send to blast
MACEPGFLRK QLAVAVKSIQ WSYAIFWSPS SRQHGVLEWC DGYYNGDIKT RKTVQAEDVH 60 VDNMGLHRSE QLRELYRSLL EGESEQRTKK PPASLSPEDL SDAEWYYLVC MSFFFNQGQG 120 LPGRALADDR TIWLCNAQYA ESTVFSRSLL AKSASIQTVV CFPYLGGVIE LGVTEQVSED 180 PSLLQHVKDF LLKFSKPICS KKPSSAAYKD DNGKEPMTAK SDNEIVEVLA MENLYCSTAV 240 KFDGKSVNGI QRKNNEFGID SLDDFSNGCE QYHPMEDTLR LEGAEGGASR FQSLQFLDDD 300 FSYGFQDSMN PSDCISEALA NQEKVSSSPR LKDANNLPLK EHQNPNHTQS GSLDPSSDED 360 MHYKRTIFTI LGSSTQLVGS PLLHNFSNRS NFIPWKKVVA ETHTPPMQQR MLKKILFAVP 420 LLSAGSLKGL KDEEQSILKQ GNNDSCTKNA TLDKLKENEK FMALKSMLPS LNEINKVSIL 480 NDTIKYLKML EARVQELETC MDSLYYEERF RRKYLDMVEQ TSDNYDYEKI EGSLKPSTNK 540 RKACEMDETD LKLKNDFPKV GRKLDVKVSM EEHEVLVDMH CPYREYILVD VMDALNDLQL 600 DAYSVQSSDH NGLFSLTLKS KFRGMAAASV GMIKLALLKV VNKS*

Sequence ? help Back to Top

Protein Sequence Length: 645 aa Download sequence Send to blast

MACEPGFLRK QLAVAVKSIQ WSYAIFWSPS SRQHGVLEWC DGYYNGDIKT RKTVQAEDVH  60
VDNMGLHRSE QLRELYRSLL EGESEQRTKK PPASLSPEDL SDAEWYYLVC MSFFFNQGQG  120
LPGRALADDR TIWLCNAQYA ESTVFSRSLL AKSASIQTVV CFPYLGGVIE LGVTEQVSED  180
PSLLQHVKDF LLKFSKPICS KKPSSAAYKD DNGKEPMTAK SDNEIVEVLA MENLYCSTAV  240
KFDGKSVNGI QRKNNEFGID SLDDFSNGCE QYHPMEDTLR LEGAEGGASR FQSLQFLDDD  300
FSYGFQDSMN PSDCISEALA NQEKVSSSPR LKDANNLPLK EHQNPNHTQS GSLDPSSDED  360
MHYKRTIFTI LGSSTQLVGS PLLHNFSNRS NFIPWKKVVA ETHTPPMQQR MLKKILFAVP  420
LLSAGSLKGL KDEEQSILKQ GNNDSCTKNA TLDKLKENEK FMALKSMLPS LNEINKVSIL  480
NDTIKYLKML EARVQELETC MDSLYYEERF RRKYLDMVEQ TSDNYDYEKI EGSLKPSTNK  540
RKACEMDETD LKLKNDFPKV GRKLDVKVSM EEHEVLVDMH CPYREYILVD VMDALNDLQL  600
DAYSVQSSDH NGLFSLTLKS KFRGMAAASV GMIKLALLKV VNKS*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4rqw_A	2e-16	8	191	9	192	Transcription factor MYC3
4rqw_B	2e-16	8	191	9	192	Transcription factor MYC3
4rru_A	2e-16	8	187	48	227	Transcription factor MYC3
4rs9_A	2e-16	8	191	9	192	Transcription factor MYC3
4ywc_A	2e-16	8	187	48	227	Transcription factor MYC3
4ywc_B	2e-16	8	187	48	227	Transcription factor MYC3
4yz6_A	2e-16	8	191	9	192	Transcription factor MYC3
Search in ModeBase

Function -- GeneRIF ? help Back to Top
Fine mapping indicated that Csgl3 is the candidate gene at the fsd6.2 locus. This locus controls high fruit spine density in natural cucumbers [PMID: 30242492]

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	JN190488	0.0	JN190488.1 Cucumis sativus GL3 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011656339.1	0.0	PREDICTED: transcription factor EGL1 isoform X2
TrEMBL	I6N8K6	0.0	I6N8K6_CUCSA; GL3
STRING	XP_004138502.1	0.0	(Cucumis sativus)
STRING	XP_004168375.1	0.0	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF2444	34	63

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G41315.1	1e-149	bHLH family protein

Link Out ? help Back to Top
Phytozome	Cucsa.135510.1
Entrez Gene	101222463

Publications ? help Back to Top
Bo K, et al. Novel loci fsd6.1 and Csgl3 regulate ultra-high fruit spine density in cucumber. Theor. Appl. Genet., 2019. 132(1): p. 27-40 [PMID:30242492]