PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

G2-like

Protein Properties

Length: 337aa MW: 36838.1 Da PI: 5.8557

Description

G2-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.117700.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	G2-like	95.1	5.4e-30	157	210	1	55
G2-like 1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 +prl+Wtp+LH+rFv++v++L G+++A+Pkti++lm+v+gLt+e+v+SHLQkYRl Cucsa.117700.1 157 RPRLVWTPQLHKRFVDVVAHL-GIKNAVPKTIMQLMNVEGLTRENVASHLQKYRL 210 59*****************.******************************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	1.67E-19	154	214	IPR009057	Homeodomain-like
PROSITE profile	PS51294	10.061	154	213	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	3.7E-30	156	215	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	1.7E-23	158	210	IPR006447	Myb domain, plants
Pfam	PF00249	6.0E-8	160	209	IPR001005	SANT/Myb domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0042753	Biological Process	positive regulation of circadian rhythm
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 337 aa Download sequence Send to blast
MGEEVKMAEY ESGGGVGGED ESCAHEERVF EWETGLPDAD DLTPLSQTLI PPELASAFSI 60 STGPCRTLMD VNRASQNTLS NLRGFQAQAF SSNNFKSFND DRTQDHDAMV VEGDEATERD 120 AGSDSRKLRK VDCAEEADSA LRTDNSMDDP SARTLKRPRL VWTPQLHKRF VDVVAHLGIK 180 NAVPKTIMQL MNVEGLTREN VASHLQKYRL YLKRMQGSSN EGPSSPDRIF ASTPVPPTLH 240 ESTNSGQANG NGHLPVPTPM PYGPPMMPMP VLGMAASGHA HSYMGMPVAH PGSAQGYPGF 300 ETHPFNMMHQ RDWSGNKYSS IVPYPHPHVP PNTNDK*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5lxu_A	7e-35	157	213	1	57	Transcription factor LUX
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that is essential for the generation of the circadian clock oscillation. Is necessary for activation of CCA1 and LHY expression. Is coregulated with TOC1 and seems to be repressed by CCA1 and LHY by direct binding of these proteins to the evening element in the LUX promoter. Directly regulates the expression of PRR9, a major component of the morning transcriptional feedback circuit, by binding specific sites on PRR9 promoter. Binds to its own promoter, inducing a negative auto-regulatory feedback loop within the core clock. Binds to ELF3 and associates with ELF4 in a diurnal complex which is required for the expression of the growth-promoting transcription factors PIF4 and PIF5 and subsequent hypocotyl growth in the early evening. {ECO:0000269\|PubMed:16006522, ECO:0000269\|PubMed:16164597, ECO:0000269\|PubMed:21236673, ECO:0000269\|PubMed:21753751, ECO:0000269\|PubMed:22311777}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00014	PBM	Transfer from AT3G46640	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Circadian oscillation with peaks at subjective dusk. {ECO:0000269\|PubMed:16006522, ECO:0000269\|PubMed:16164597, ECO:0000269\|PubMed:17132630, ECO:0000269\|PubMed:21753751}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681926	0.0	LN681926.1 Cucumis melo genomic scaffold, anchoredscaffold00044.
GenBank	LN713266	0.0	LN713266.1 Cucumis melo genomic chromosome, chr_12.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011658264.1	0.0	PREDICTED: transcription factor PCL1-like
Refseq	XP_011658269.1	0.0	PREDICTED: transcription factor PCL1-like
Swissprot	Q9SNB4	5e-84	PCL1_ARATH; Transcription factor LUX
TrEMBL	A0A0A0LXF6	0.0	A0A0A0LXF6_CUCSA; Uncharacterized protein
STRING	XP_004145284.1	0.0	(Cucumis sativus)
STRING	XP_004169758.1	0.0	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF6957	33	47

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G46640.2	1e-79	G2-like family protein

Link Out ? help Back to Top
Phytozome	Cucsa.117700.1
Entrez Gene	101205712

Publications ? help Back to Top
Ren Y, et al. An integrated genetic and cytogenetic map of the cucumber genome. PLoS ONE, 2009. 4(6): p. e5795 [PMID:19495411] Guo S, et al. Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics, 2010. 11: p. 384 [PMID:20565788] Li Z, et al. RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics, 2011. 12: p. 540 [PMID:22047402] Higham CF,Husmeier D A Bayesian approach for parameter estimation in the extended clock gene circuit of Arabidopsis thaliana. BMC Bioinformatics, 2013. 14 Suppl 10: p. S3 [PMID:24267177]