PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

Nin-like

Protein Properties

Length: 1004aa MW: 110694 Da PI: 5.7162

Description

Nin-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.114750.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	RWP-RK	92.3	3.5e-29	599	650	1	52
RWP-RK 1 aekeisledlskyFslpikdAAkeLgvclTvLKriCRqyGIkRWPhRkiksl 52 aek+isle+l++yF++++kdAAk+Lgvc+T++KriCRq+GI+RWP+Rki+++ Cucsa.114750.1 599 AEKSISLEVLQQYFAGSLKDAAKSLGVCPTTMKRICRQHGISRWPSRKINKV 650 589***********************************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51519	17.871	589	670	IPR003035	RWP-RK domain
Pfam	PF02042	3.8E-26	603	650	IPR003035	RWP-RK domain
SuperFamily	SSF54277	4.58E-23	901	989	No hit	No description
SMART	SM00666	3.2E-25	907	989	IPR000270	PB1 domain
PROSITE profile	PS51745	25.938	907	989	IPR000270	PB1 domain
CDD	cd06407	6.43E-37	908	988	No hit	No description
Pfam	PF00564	7.9E-19	908	988	IPR000270	PB1 domain
Gene3D	G3DSA:3.10.20.240	1.9E-25	908	988	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009414	Biological Process	response to water deprivation
GO:0010118	Biological Process	stomatal movement
GO:0010167	Biological Process	response to nitrate
GO:0042128	Biological Process	nitrate assimilation
GO:0005634	Cellular Component	nucleus
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 1004 aa Download sequence Send to blast
MTEPDSDHPS PLFPKSNHRS SSDDRTPLMD FDLDLDIPWP LDQIPSFGSN PMSPFLLSTS 60 DHLASPLWAF SEADDDDDSK FAAYACSVLG TSNSHSVPQK PTENQKFKIL PVPSSSWGVL 120 PSENPDGYCL IKEKMAQALR YIKESSDQHV LAQVWAPVKS GGKLVLSTSG QPFFLDSQSN 180 GLHQYRMASL TFSFSLDADQ DGYLGLPGRV FQQKLPEWTP NVQYYSSKEY PRLSHALNYN 240 VQGTLALPVF DPSGHSCLGV LELIMTSPKI NYAPEVDKVC KALEAVNLKS SEILDHPNNQ 300 IQSWQCLSNQ ICNEGRQNAL AEILEVLTVV CETHNLPLAQ TWVPCRHRNV LANGGGLKKS 360 CTSFDGSCMG RICMSATEVA SYVVDAHMWG FRDACLEHHL QKGQGVSGRA FLSHSSCFCG 420 DVTQFCKTEY PLVHYALMFG LKSCFSICLR STFTGDDEYI LEFFLPPSIV DYQEQKNLLG 480 ALMATMKKHF YTLKVASGIN LEDKEGLVEI IQASRNGGFD SRFEYIQIPR PVQLPPASDA 540 MPKAVEVAAL ETLEQQSLMV HDAPKDENNG AWDGESHKSV PCPQNKEVKK TSERKRGKAE 600 KSISLEVLQQ YFAGSLKDAA KSLGVCPTTM KRICRQHGIS RWPSRKINKV NRSLSKLKRV 660 IESVQGAEGA FGISSLATSP LPVTVSSSSH PLTPEGSNQQ NFVASQPSDS QYKETNTPEA 720 QTNDTQARLE DRLHRGVLSP EEPIHEQNGF LPKFGNGLNN FRTGSGSREE SAGTPTSHGS 780 CQGSPANDSA LANNPISIRQ HEQCARRESP EVAFHPIDKL NISAPPCSIP DTLVMVEPEE 840 PFGGMLIEDA GSSKDLKNLC ASVADAVLDE QVPEFCWSNH HDIALRQPMD SVCHTVPHIS 900 LRQEPRRMTI KATYKEDIIR FRIPLTSGIV ELREEVAKRL KLEVGTFDIK YMDDDREWVL 960 IACDADLQEC VDISKSSGSN IIRLSVHDLN VNLGSSCEST GGE*

Sequence ? help Back to Top

Protein Sequence Length: 1004 aa Download sequence Send to blast

MTEPDSDHPS PLFPKSNHRS SSDDRTPLMD FDLDLDIPWP LDQIPSFGSN PMSPFLLSTS  60
DHLASPLWAF SEADDDDDSK FAAYACSVLG TSNSHSVPQK PTENQKFKIL PVPSSSWGVL  120
PSENPDGYCL IKEKMAQALR YIKESSDQHV LAQVWAPVKS GGKLVLSTSG QPFFLDSQSN  180
GLHQYRMASL TFSFSLDADQ DGYLGLPGRV FQQKLPEWTP NVQYYSSKEY PRLSHALNYN  240
VQGTLALPVF DPSGHSCLGV LELIMTSPKI NYAPEVDKVC KALEAVNLKS SEILDHPNNQ  300
IQSWQCLSNQ ICNEGRQNAL AEILEVLTVV CETHNLPLAQ TWVPCRHRNV LANGGGLKKS  360
CTSFDGSCMG RICMSATEVA SYVVDAHMWG FRDACLEHHL QKGQGVSGRA FLSHSSCFCG  420
DVTQFCKTEY PLVHYALMFG LKSCFSICLR STFTGDDEYI LEFFLPPSIV DYQEQKNLLG  480
ALMATMKKHF YTLKVASGIN LEDKEGLVEI IQASRNGGFD SRFEYIQIPR PVQLPPASDA  540
MPKAVEVAAL ETLEQQSLMV HDAPKDENNG AWDGESHKSV PCPQNKEVKK TSERKRGKAE  600
KSISLEVLQQ YFAGSLKDAA KSLGVCPTTM KRICRQHGIS RWPSRKINKV NRSLSKLKRV  660
IESVQGAEGA FGISSLATSP LPVTVSSSSH PLTPEGSNQQ NFVASQPSDS QYKETNTPEA  720
QTNDTQARLE DRLHRGVLSP EEPIHEQNGF LPKFGNGLNN FRTGSGSREE SAGTPTSHGS  780
CQGSPANDSA LANNPISIRQ HEQCARRESP EVAFHPIDKL NISAPPCSIP DTLVMVEPEE  840
PFGGMLIEDA GSSKDLKNLC ASVADAVLDE QVPEFCWSNH HDIALRQPMD SVCHTVPHIS  900
LRQEPRRMTI KATYKEDIIR FRIPLTSGIV ELREEVAKRL KLEVGTFDIK YMDDDREWVL  960
IACDADLQEC VDISKSSGSN IIRLSVHDLN VNLGSSCEST GGE*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in regulation of nitrate assimilation and in transduction of the nitrate signal. {ECO:0000269\|PubMed:18826430}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00449	DAP	Transfer from AT4G24020	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not regulated by the N source or by nitrate. {ECO:0000269\|PubMed:18826430}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681873	0.0	LN681873.1 Cucumis melo genomic scaffold, anchoredscaffold00027.
GenBank	LN713261	0.0	LN713261.1 Cucumis melo genomic chromosome, chr_7.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011653226.1	0.0	PREDICTED: protein NLP7-like isoform X1
Swissprot	Q84TH9	0.0	NLP7_ARATH; Protein NLP7
TrEMBL	A0A0A0KX54	0.0	A0A0A0KX54_CUCSA; Uncharacterized protein
STRING	XP_008451916.1	0.0	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF4257	34	56

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G24020.1	0.0	NIN like protein 7

Link Out ? help Back to Top
Phytozome	Cucsa.114750.1
Entrez Gene	101212500

Publications ? help Back to Top
Ren Y, et al. An integrated genetic and cytogenetic map of the cucumber genome. PLoS ONE, 2009. 4(6): p. e5795 [PMID:19495411] Guo S, et al. Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics, 2010. 11: p. 384 [PMID:20565788] Li Z, et al. RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics, 2011. 12: p. 540 [PMID:22047402] Xu N, et al. The Arabidopsis NRG2 Protein Mediates Nitrate Signaling and Interacts with and Regulates Key Nitrate Regulators. Plant Cell, 2016. 28(2): p. 485-504 [PMID:26744214] Karve R,Suárez-Román F,Iyer-Pascuzzi AS The Transcription Factor NIN-LIKE PROTEIN7 Controls Border-Like Cell Release. Plant Physiol., 2016. 171(3): p. 2101-11 [PMID:27221617] Yu LH, et al. Overexpression of Arabidopsis NLP7 improves plant growth under both nitrogen-limiting and -sufficient conditions by enhancing nitrogen and carbon assimilation. Sci Rep, 2016. 6: p. 27795 [PMID:27293103] Menz J,Li Z,Schulze WX,Ludewig U Early nitrogen-deprivation responses in Arabidopsis roots reveal distinct differences on transcriptome and (phospho-) proteome levels between nitrate and ammonium nutrition. Plant J., 2016. 88(5): p. 717-734 [PMID:27419465] Yan D, et al. NIN-like protein 8 is a master regulator of nitrate-promoted seed germination in Arabidopsis. Nat Commun, 2016. 7: p. 13179 [PMID:27731416] Guan P, et al. Interacting TCP and NLP transcription factors control plant responses to nitrate availability. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(9): p. 2419-2424 [PMID:28202720] Liu KH, et al. Discovery of nitrate-CPK-NLP signalling in central nutrient-growth networks. Nature, 2017. 545(7654): p. 311-316 [PMID:28489820] Li Z, et al. The Arabidopsis CPSF30-L gene plays an essential role in nitrate signaling and regulates the nitrate transceptor gene NRT1.1. New Phytol., 2017. 216(4): p. 1205-1222 [PMID:28850721] Cao H, et al. Overexpression of the Maize ZmNLP6 and ZmNLP8 Can Complement the Arabidopsis Nitrate Regulatory Mutant nlp7 by Restoring Nitrate Signaling and Assimilation. Front Plant Sci, 2017. 8: p. 1703 [PMID:29051766] Konishi N,Okubo T,Yamaya T,Hayakawa T,Minamisawa K Nitrate Supply-Dependent Shifts in Communities of Root-Associated Bacteria in Arabidopsis. Microbes Environ., 2017. 32(4): p. 314-323 [PMID:29187692] Karve RA,Iyer-Pascuzzi AS Further insights into the role of NIN-LIKE PROTEIN 7 (NLP7) in root cap cell release. Plant Signal Behav, 2018. 13(1): p. e1414122 [PMID:29215953] Zhao L, et al. The Arabidopsis NLP7 gene regulates nitrate signaling via NRT1.1-dependent pathway in the presence of ammonium. Sci Rep, 2018. 8(1): p. 1487 [PMID:29367694]