PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cucsa.086330.4

Common Name

Csa_1G065960, LOC101208894

Organism

Cucumis sativus

Taxonomic ID

3659

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

bHLH

Protein Properties

Length: 182aa MW: 20432.4 Da PI: 10.355

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.086330.4	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	33	1.1e-10	26	71	6	54
HHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 6 nerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 E+ RRd++N++f eL ++l + + +K +K++iL Av+ I +L Cucsa.086330.4 26 ARKEKIRRDKLNDRFLELNSILNHG---RPPKIDKSAILGDAVRMIIQL 71 568*******************8...89**************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	11.395	20	71	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	3.95E-7	23	76	No hit	No description
Pfam	PF00010	2.8E-8	25	71	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.1E-6	26	77	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.23E-12	27	94	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	5.7E-11	28	93	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 182 aa Download sequence Send to blast
MEEDVKESRS RKRMSSGSSN AFESKARKEK IRRDKLNDRF LELNSILNHG RPPKIDKSAI 60 LGDAVRMIIQ LRDEAQKLKE SNESSLEKIN EMKAEKNELR DEKQRLKEAK DSLEKKMKGF 120 NTQPTFLPHP PAIPAGFSSP NQIVGGKLVP VIGYPGVSMW QFMPPGAIDT SQDHVLRPPV 180 A*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	26	33	RKEKIRRD

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681932	1e-136	LN681932.1 Cucumis melo genomic scaffold, anchoredscaffold00001.
GenBank	LN713266	1e-136	LN713266.1 Cucumis melo genomic chromosome, chr_12.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004145091.1	1e-128	PREDICTED: transcription factor ILR3-like
Swissprot	Q9FH37	1e-72	ILR3_ARATH; Transcription factor ILR3
TrEMBL	A0A0A0LX71	1e-127	A0A0A0LX71_CUCSA; Uncharacterized protein
STRING	XP_004145091.1	1e-127	(Cucumis sativus)
STRING	XP_004154169.1	1e-127	(Cucumis sativus)
STRING	XP_004167401.1	1e-127	(Cucumis sativus)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	3e-71	bHLH family protein

Link Out ? help Back to Top
Phytozome	Cucsa.086330.4
Entrez Gene	101208894

Publications ? help Back to Top
Ren Y, et al. An integrated genetic and cytogenetic map of the cucumber genome. PLoS ONE, 2009. 4(6): p. e5795 [PMID:19495411] Guo S, et al. Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics, 2010. 11: p. 384 [PMID:20565788] Li Z, et al. RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics, 2011. 12: p. 540 [PMID:22047402] Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]