PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

HD-ZIP

Protein Properties

Length: 645aa MW: 72982.3 Da PI: 6.4094

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.061970.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	68	1.2e-21	109	164	1	56
TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 r+k +++t+eq++e+e+lF+++++p++++r++L+k+lgL+ rqVk+WFqNrR++ k Cucsa.061970.1 109 RKKYHRHTTEQIREMEALFKESPHPDEKQRQQLSKRLGLSPRQVKFWFQNRRTQIK 164 7999************************************************9877 PP
2	START	213.9	5.6e-67	284	510	4	206
HHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS..........SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEE CS START 4 eeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv.........dsgealrasgvvdmvlallveellddkeqWdetla....kaet 81 ea +el ++a+a++p+Wv+s+ e++n+de+l++f+ s++ ++ea+r++++v+m++ +lv++++d + qW+e+++ ka+t Cucsa.061970.1 284 DEAVEELKTMAAAGDPLWVRSVetgrEILNYDEYLKTFQFSNNnsntrnclkTHIEASRETALVFMEPSRLVQSFMDEN-QWKEMFPfmisKAAT 377 578999******************************9888899******************************.*********** PP EEEECTT.......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE CS START 82 levissg.......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwve 168 ++vi++g ga+qlm+ae q+l+plvp R+ +f+R+++ql a++w+ivdvS+++ ++++ + s+v+ +++pSg++i+++sngh+kvt+ve Cucsa.061970.1 378 VDVICNGeaakwnnGAVQLMFAEVQMLTPLVPtREMYFIRHCKQLDAEQWAIVDVSIENVEDNNIDVSLVKYRKRPSGCIIKDESNGHCKVTMVE 472 ***********************************************************99************************** PP -EE--SSXXHHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS START 169 hvdlkgrlphwllrslvksglaegaktwvatlqrqcek 206 h ++ ++ +h+l+rs+v++g+a+ga++w+atlq qce+ Cucsa.061970.1 473 HLECVKNKVHNLYRSIVNNGTAFGARHWMATLQLQCER 510 **********************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	5.43E-21	99	167	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	3.7E-21	104	160	IPR009057	Homeodomain-like
PROSITE profile	PS50071	18.091	106	166	IPR001356	Homeobox domain
SMART	SM00389	6.7E-19	108	170	IPR001356	Homeobox domain
Pfam	PF00046	6.6E-19	109	164	IPR001356	Homeobox domain
CDD	cd00086	2.70E-18	109	164	No hit	No description
PROSITE pattern	PS00027	0	141	164	IPR017970	Homeobox, conserved site
PROSITE profile	PS50848	33.915	272	513	IPR002913	START domain
SuperFamily	SSF55961	3.85E-31	275	510	No hit	No description
CDD	cd08875	1.21E-102	277	509	No hit	No description
SMART	SM00234	1.5E-58	280	510	IPR002913	START domain
Pfam	PF01852	5.5E-54	284	510	IPR002913	START domain
SuperFamily	SSF55961	3.02E-7	554	629	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0008289	Molecular Function	lipid binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 645 aa Download sequence Send to blast
MSNNNNTNNP LAFTKDFFSS PALSLTLAGI FRRSDHEVGD VEMEEVDDGS VGGARRDNHD 60 TMTAEVSSEN SGPVVRSRSE EEEEEEEEGG GQDDQENELV DHGCQLKRRK KYHRHTTEQI 120 REMEALFKES PHPDEKQRQQ LSKRLGLSPR QVKFWFQNRR TQIKAIQERH ENTLLKAEME 180 KLREENKAMR EISKKKIGCP NCGTADATQD DLVFTTTEQL RIKNAKLKAE VEKLRAALGK 240 YPQAAASPST YSSGNEQETS NRICLDFYTG IFGLENSRIM EKVDEAVEEL KTMAAAGDPL 300 WVRSVETGRE ILNYDEYLKT FQFSNNNSNT RNCLKTHIEA SRETALVFME PSRLVQSFMD 360 ENQWKEMFPF MISKAATVDV ICNGEAAKWN NGAVQLMFAE VQMLTPLVPT REMYFIRHCK 420 QLDAEQWAIV DVSIENVEDN NIDVSLVKYR KRPSGCIIKD ESNGHCKVTM VEHLECVKNK 480 VHNLYRSIVN NGTAFGARHW MATLQLQCER SAFFMATNIP MKDSTGVSTL AGRKSTLKLA 540 QRMSCSFSQA VAASSYQTWT KVVGKSGEDI RVCSRKNLSD PGEPIGVILC AVSSLWLPLS 600 PHLLFDFFRD ESRRSQWDAM FGGDKAKTIA NLAKGQDRGN SVTIQ

Sequence ? help Back to Top

Protein Sequence Length: 645 aa Download sequence Send to blast

MSNNNNTNNP LAFTKDFFSS PALSLTLAGI FRRSDHEVGD VEMEEVDDGS VGGARRDNHD  60
TMTAEVSSEN SGPVVRSRSE EEEEEEEEGG GQDDQENELV DHGCQLKRRK KYHRHTTEQI  120
REMEALFKES PHPDEKQRQQ LSKRLGLSPR QVKFWFQNRR TQIKAIQERH ENTLLKAEME  180
KLREENKAMR EISKKKIGCP NCGTADATQD DLVFTTTEQL RIKNAKLKAE VEKLRAALGK  240
YPQAAASPST YSSGNEQETS NRICLDFYTG IFGLENSRIM EKVDEAVEEL KTMAAAGDPL  300
WVRSVETGRE ILNYDEYLKT FQFSNNNSNT RNCLKTHIEA SRETALVFME PSRLVQSFMD  360
ENQWKEMFPF MISKAATVDV ICNGEAAKWN NGAVQLMFAE VQMLTPLVPT REMYFIRHCK  420
QLDAEQWAIV DVSIENVEDN NIDVSLVKYR KRPSGCIIKD ESNGHCKVTM VEHLECVKNK  480
VHNLYRSIVN NGTAFGARHW MATLQLQCER SAFFMATNIP MKDSTGVSTL AGRKSTLKLA  540
QRMSCSFSQA VAASSYQTWT KVVGKSGEDI RVCSRKNLSD PGEPIGVILC AVSSLWLPLS  600
PHLLFDFFRD ESRRSQWDAM FGGDKAKTIA NLAKGQDRGN SVTIQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor required for correct morphological development and maturation of trichomes as well as for normal development of seed coat mucilage. Regulates the frequency of trichome initiation and determines trichome spacing. {ECO:0000269\|PubMed:11844112}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated by GEM. {ECO:0000269\|PubMed:17450124}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KM095653	0.0	KM095653.1 Cucumis sativus multicellular trichome development class IV homeodomain-leucine zipper transcription factor (Gl-2) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008447518.1	0.0	PREDICTED: homeobox-leucine zipper protein GLABRA 2-like isoform X1
Swissprot	P46607	0.0	HGL2_ARATH; Homeobox-leucine zipper protein GLABRA 2
TrEMBL	A0A097A1M3	0.0	A0A097A1M3_CUCSA; Multicellular trichome development class IV homeodomain-leucine zipper transcription factor
STRING	XP_004151038.1	0.0	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF4714	33	52

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G79840.1	0.0	HD-ZIP family protein

Link Out ? help Back to Top
Phytozome	Cucsa.061970.1

Publications ? help Back to Top
Wu R,Citovsky V Adaptor proteins GIR1 and GIR2. I. Interaction with the repressor GLABRA2 and regulation of root hair development. Biochem. Biophys. Res. Commun., 2017. 488(3): p. 547-553 [PMID:28526410]