PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Csa20g035800.1
Organism
Camelina sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina
Family E2F/DP
Protein Properties Length: 473aa    MW: 51644.2 Da    PI: 4.5143
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Csa20g035800.1genomeCSGPView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP86.51.9e-27133198171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                     r+++sL+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liek+ kn+i+wkg
  Csa20g035800.1 133 RYDSSLGLLTKKFINLIKQAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIQWKG 198
                     6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.9E-29130200IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.72E-17133196IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013725.9E-35133198IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.6E-24135198IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146608.66E-45209315No hitNo description
SuperFamilySSF1440741.7E-31210315No hitNo description
PfamPF164211.4E-31214313IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 473 aa     Download sequence    Send to blast
MSEEPQQFPP SKRQHHPSLS SMKPPLVAPG EYHRFDSAET RLAGGGAAPA PADHAVSDSI  60
VIKSTLKRKT DAVNQIAEPN ELSTCVLQTP VSGKGGKAKK TSRSAKSNKS GTLASGSNAG  120
SPGNNFTQAG TCRYDSSLGL LTKKFINLIK QAEDGILDLN KAADTLEVQK RRIYDITNVL  180
EGIGLIEKTL KNRIQWKGLD VSKPGETIEN IANLQDEVRN LTVEEAKLDD QIRESQDRLT  240
SLSEDENNKR LLFVTEDDIK NLPCFQNKTL IAVKAPHGTT LEVPDPDEAG GYSQRRYRII  300
LRSTMGPIDV YLVSQFEESF EDIPHADEPS NAPAEPSSVP DEPSNLPSTS GLPENHDVAM  360
PMEEDSTGRK MEIQELDDTQ RVYSDIESHD FVDGIMKIVP PDLDMGVDYW LRSEVGEVSI  420
TDLWPDESGP DWNHMGSFDQ NHAGPSNTTL EQPQTPSSPT PEDSTGTRST GS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A1e-24133199774PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00661PBMTransfer from Pp3c1_6880Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapCsa20g035800.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAJ2945330.0AJ294533.1 Arabidopsis thaliana mRNA for E2F-related protein (e2Fb gene).
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010493297.10.0PREDICTED: transcription factor E2FB
SwissprotQ9FV710.0E2FB_ARATH; Transcription factor E2FB
TrEMBLR0FJU80.0R0FJU8_9BRAS; Uncharacterized protein
STRINGXP_010493297.10.0(Camelina sativa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM80828121
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.20.0E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]