PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina

Family

HD-ZIP

Protein Properties

Length: 676aa MW: 74390.6 Da PI: 7.2375

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Csa17g043680.1	genome	CSGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	59.3	6.5e-19	20	78	3	57
--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS Homeobox 3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57 k ++t+eq+e+Le++++++++ps +r++L +++ +++ rq+kvWFqNrR +ek+ Csa17g043680.1 20 KYVRYTPEQVEALERVYAECPKPSSLRRQQLIRECpilcNIEPRQIKVWFQNRRCREKQ 78 5678*****************************************************97 PP
2	START	170.8	9.2e-54	141	346	5	205
HHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EEEEEEEEX CS START 5 eaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..galqlmvae 97 e+++e+++ka+ ++ Wv++ +++g++++ +++ s+++sg a+ra+g+v +++ v+e+l+d++ W ++++ +etl+vi +g g+++l + + Csa17g043680.1 141 ETLAEFLSKATGTAVDWVQMIGMKPGPDSIGIVAVSRNCSGIAARACGLVSLEPM-KVAEILKDRPSWFRDCRCVETLNVIPTGsgGTIELVNIQ 234 7889*************************************************.8888888888************************* PP XTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHHHHHHH CS START 98 lqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrslvksg 188 +a+++l++ Rdf+++Ry+ +l++g++v++++S++s + p+ sss+vRa++l Sg+li+p+++g+s +++v+hvdl+ ++++++lr+l++s+ Csa17g043680.1 235 IYAPTTLAAaRDFWTLRYSTSLEDGSYVVCERSLTSATGGPNgplSSSFVRAKMLSSGFLIRPCDGGGSIIHIVDHVDLDVSSVPEVLRPLYESS 329 *************************************99************************************************ PP HHHHHHHHHHHTXXXXX CS START 189 laegaktwvatlqrqce 205 + ++k++va+l++ ++ Csa17g043680.1 330 KILAQKMTVAALRHVRQ 346 **********98765 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50071	15.451	15	79	IPR001356	Homeobox domain
SMART	SM00389	4.2E-16	17	83	IPR001356	Homeobox domain
SuperFamily	SSF46689	1.07E-16	19	81	IPR009057	Homeodomain-like
CDD	cd00086	3.94E-17	20	80	No hit	No description
Pfam	PF00046	1.7E-16	21	78	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	6.0E-19	22	78	IPR009057	Homeodomain-like
CDD	cd14686	2.44E-6	72	111	No hit	No description
PROSITE profile	PS50848	22.643	128	356	IPR002913	START domain
SMART	SM00234	3.7E-49	137	347	IPR002913	START domain
Gene3D	G3DSA:3.30.530.20	6.9E-19	139	342	IPR023393	START-like domain
CDD	cd08875	2.27E-67	140	348	No hit	No description
Pfam	PF01852	6.1E-51	141	346	IPR002913	START domain
SuperFamily	SSF55961	2.2E-33	141	349	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding
GO:0008289	Molecular Function	lipid binding

Sequence ? help Back to Top
Protein Sequence Length: 676 aa Download sequence Send to blast
MMAHSMDDRD SPDKGFDSGK YVRYTPEQVE ALERVYAECP KPSSLRRQQL IRECPILCNI 60 EPRQIKVWFQ NRRCREKQRK ESARLQTVNR KLSAMNKLLM EENDRLQKQV SHLVYENGFM 120 KHRIHTASGT TTDNSCESVV ETLAEFLSKA TGTAVDWVQM IGMKPGPDSI GIVAVSRNCS 180 GIAARACGLV SLEPMKVAEI LKDRPSWFRD CRCVETLNVI PTGSGGTIEL VNIQIYAPTT 240 LAAARDFWTL RYSTSLEDGS YVVCERSLTS ATGGPNGPLS SSFVRAKMLS SGFLIRPCDG 300 GGSIIHIVDH VDLDVSSVPE VLRPLYESSK ILAQKMTVAA LRHVRQIAQE TSGEVQYSVG 360 RQPAVLRTFS QRLCRGFNDA VNGFADDGWS PMSSDGAEDI TIMINSSSAK FAGSQYGSSF 420 LPSFGSGVLC AKASMLLQNV PPLVLIRFLR EHRAEWADYG VDAYSAASLR ATPFAVPCVR 480 TGGFPSNQVI LPLAQTLEHE EFLEVVRLGG HAYSPEDMGL SRDMYLLQLC SGVDENVVGG 540 CAQLVFAPID ESFADDAPLL PSGFRVIPLE QKINPNDHQS ASRTRDLASS LDGSTKTDTE 600 TNSRLVLTIA FQFTFDNHSR DNVATMARQY VRNVVGSIQR VALAITPRPG SMQLPTSPEA 660 LTLVRWITRS YRYSS*

Sequence ? help Back to Top

Protein Sequence Length: 676 aa Download sequence Send to blast

MMAHSMDDRD SPDKGFDSGK YVRYTPEQVE ALERVYAECP KPSSLRRQQL IRECPILCNI  60
EPRQIKVWFQ NRRCREKQRK ESARLQTVNR KLSAMNKLLM EENDRLQKQV SHLVYENGFM  120
KHRIHTASGT TTDNSCESVV ETLAEFLSKA TGTAVDWVQM IGMKPGPDSI GIVAVSRNCS  180
GIAARACGLV SLEPMKVAEI LKDRPSWFRD CRCVETLNVI PTGSGGTIEL VNIQIYAPTT  240
LAAARDFWTL RYSTSLEDGS YVVCERSLTS ATGGPNGPLS SSFVRAKMLS SGFLIRPCDG  300
GGSIIHIVDH VDLDVSSVPE VLRPLYESSK ILAQKMTVAA LRHVRQIAQE TSGEVQYSVG  360
RQPAVLRTFS QRLCRGFNDA VNGFADDGWS PMSSDGAEDI TIMINSSSAK FAGSQYGSSF  420
LPSFGSGVLC AKASMLLQNV PPLVLIRFLR EHRAEWADYG VDAYSAASLR ATPFAVPCVR  480
TGGFPSNQVI LPLAQTLEHE EFLEVVRLGG HAYSPEDMGL SRDMYLLQLC SGVDENVVGG  540
CAQLVFAPID ESFADDAPLL PSGFRVIPLE QKINPNDHQS ASRTRDLASS LDGSTKTDTE  600
TNSRLVLTIA FQFTFDNHSR DNVATMARQY VRNVVGSIQR VALAITPRPG SMQLPTSPEA  660
LTLVRWITRS YRYSS*

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor involved in the determination of adaxial-abaxial polarity in ovule primordium. Specifies adaxial leaf fates. Binds to the DNA sequence 5'-GTAAT[GC]ATTAC-3'. {ECO:0000269\|PubMed:11395776, ECO:0000269\|PubMed:15598805, ECO:0000269\|PubMed:17900520, ECO:0000269\|PubMed:9747806}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Csa17g043680.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By auxin. Repressed by miR165 and miR166. {ECO:0000269\|PubMed:14999284, ECO:0000269\|PubMed:16033795, ECO:0000269\|PubMed:17237362}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AJ440967	0.0	AJ440967.1 Arabidopsis thaliana mRNA for homeodomain-leucine zipper protein (hb9 gene).
GenBank	AK226570	0.0	AK226570.1 Arabidopsis thaliana mRNA for HD-Zip protein, complete cds, clone: RAFL07-12-P11.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_019094482.1	0.0	PREDICTED: homeobox-leucine zipper protein ATHB-9-like, partial
Swissprot	O04292	0.0	ATBH9_ARATH; Homeobox-leucine zipper protein ATHB-9
TrEMBL	D7KFK4	0.0	D7KFK4_ARALL; Uncharacterized protein
STRING	XP_010480757.1	0.0	(Camelina sativa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4256	26	53

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G30490.1	0.0	HD-ZIP family protein

Publications ? help Back to Top
Jia X, et al. Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic. Plant Sci., 2015. 233: p. 11-21 [PMID:25711809] Yamada T,Sasaki Y,Hashimoto K,Nakajima K,Gasser CS CORONA, PHABULOSA and PHAVOLUTA collaborate with BELL1 to confine WUSCHEL expression to the nucellus in Arabidopsis ovules. Development, 2016. 143(3): p. 422-6 [PMID:26700684] Wójcik AM,Nodine MD,Gaj MD miR160 and miR166/165 Contribute to the LEC2-Mediated Auxin Response Involved in the Somatic Embryogenesis Induction in Arabidopsis. Front Plant Sci, 2017. 8: p. 2024 [PMID:29321785]