PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina

Family

C2H2

Protein Properties

Length: 288aa MW: 30956.8 Da PI: 8.8158

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Csa15g027510.1	genome	CSGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	14.3	0.00012	115	137	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ykC+ Cgk F++ L H +H Csa15g027510.1 115 YKCSVCGKAFPSYQALGGHKASH 137 9***********99999998887 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	1.82E-9	114	137	No hit	No description
Pfam	PF13912	1.8E-13	115	138	IPR007087	Zinc finger, C2H2
PROSITE profile	PS50157	11.801	115	142	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0043	115	137	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	2.6E-4	115	137	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	117	137	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	1.82E-9	172	199	No hit	No description
Pfam	PF13912	9.7E-14	177	201	IPR007087	Zinc finger, C2H2
PROSITE profile	PS50157	9.099	177	199	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.17	177	199	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	179	199	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 288 aa Download sequence Send to blast
MALEAMNSPS SFTTRIETKE DLMNDAVFME PWLKRKRSKR QRSHSPSSSS SSPPRSRPKS 60 QNHQDLTEEE YLALCLLMLA KDQPSSTTTQ TRFHHSQPQT QTPPPESSKT LSSSYKCSVC 120 GKAFPSYQAL GGHKASHRIK PPTVTPNPDD PSSTAAPTVS AAAAGEKHPI SASGKIHECS 180 ICHKVFPTGQ ALGGHKRCHY EGNLGGGGGG SKSISHSGSV SSTVSEERSN RGFIDLNLPA 240 LPELSLHHNP IAAVDEEILS PLTGKKPLLL TDHDQVIKKE ADLSLRI*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	32	39	LKRKRSKR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional repressor involved in the inhibition of plant growth under abiotic stress conditions. Can repress the expression of various genes, including osmotic stress and abscisic acid-repressive genes and auxin-inducible genes, by binding to their promoter regions in a DNA sequence-specific manner. Acts as a negative regulator of abscisic acid (ABA) signaling during seed germination. Probably involved in jasmonate (JA) early signaling response. May regulate the expression of the JA biosynthesis gene LOX3 and control the expression of TIFY10A/JAZ1, a key repressor in the JA signaling cascade. May act as a positive regulator of leaf senescence. Has been identified as a suppressor of the deficiency of yeast snf4 mutant to grow on non-fermentable carbon source. {ECO:0000269\|PubMed:10929106, ECO:0000269\|PubMed:15333755, ECO:0000269\|PubMed:18216250, ECO:0000269\|PubMed:20619483, ECO:0000269\|PubMed:21852415, ECO:0000269\|PubMed:22709441}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Csa15g027510.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By abscisic acid (ABA), ethylene, salt, cold, dehydration and the monovalent and divalent cations Li(+), Na(+), K(+), Cs(+), Ca(2+) and Mg(2+). {ECO:0000269\|PubMed:10806347, ECO:0000269\|PubMed:15333755, ECO:0000269\|PubMed:20619483, ECO:0000269\|PubMed:21852415}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010466108.1	0.0	PREDICTED: zinc finger protein AZF2
Swissprot	Q9SSW2	1e-127	AZF2_ARATH; Zinc finger protein AZF2
TrEMBL	D7LA10	1e-125	D7LA10_ARALL; Uncharacterized protein
STRING	XP_010466108.1	0.0	(Camelina sativa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM10272	18	29

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G19580.2	1e-104	zinc-finger protein 2

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Ortiz-Espín A, et al. Mitochondrial AtTrxo1 is transcriptionally regulated by AtbZIP9 and AtAZF2 and affects seed germination under saline conditions. J. Exp. Bot., 2017. 68(5): p. 1025-1038 [PMID:28184497]